Results 1 to 10 of about 8,774 (186)
Autopsy and Case Reports, 2015 Hereditary hemochromatosis (HH) is the most commonly identified autosomal recessive genetic disorder in the white population, characterized by increased intestinal iron absorption and secondary abnormal accumulation in parenchymal organs, not ...
Stephen A. Geller +1 more
doaj +3 more sources
Case Report: Secukinumab for the treatment of severe psoriasis in a patient with hereditary hemochromatosis [PDF]
Frontiers in MedicineThere are several comorbidities associated with psoriasis, including genetic disorders such as hereditary hemochromatosis, which can lead to organ damage secondary to iron overload.
Yingzhe Yu +4 more
doaj +2 more sources
Case report: A rare case of hereditary hemochromatosis caused by a mutation in the HAMP gene in Fuyang, China [PDF]
Frontiers in MedicineHemochromatosis, also known as siderosis, is a disease caused by excessive iron deposition in human organs and tissues, resulting from iron metabolism disorders.
Jinling Wang +9 more
doaj +2 more sources
[Hereditary Hemochromatosis]. [PDF]
Acta Gastroenterol Latinoam, 2023 Yamasato F, Daruich J.
europepmc +2 more sources
Iron Metabolism in the Disorders of Heme Biosynthesis
Metabolites, 2022 Given its remarkable property to easily switch between different oxidative states, iron is essential in countless cellular functions which involve redox reactions. At the same time, uncontrolled interactions between iron and its surrounding milieu may be
Andrea Ricci +5 more
doaj +1 more source
Acta Marisiensis - Seria Medica, 2022 Objective: Hereditary hemochromatosis, or primary hemochromatosis, is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and ...
Sigmirean Victor
doaj +1 more source
Hemochromatosis - modern condition of the problem [PDF]
Терапевтический архив, 2018 The iron overload syndrome can be associated with various acquired states and hereditary factors. Hereditary hemochromatosis is the most common genetic disorder. Without therapeutic intervention the disease can lead to the development of life-threatening
N B Voloshina +3 more
doaj +1 more source
Journal of Medical Case Reports, 2020 Introduction Hereditary hemochromatosis is an inherited disorder of iron metabolism, characterized by excessive iron deposition in major organs of the body, leading to multi-organ dysfunction. It is a genetically heterogeneous disease caused by mutations
Wasanthi Wickramasinghe +3 more
doaj +1 more source
Pathophysiology of Hereditary Hemochromatosis [PDF]
Seminars in Liver Disease, 2005 Hereditary hemochromatosis (HH) encompasses several inherited disorders of iron homeostasis characterized by increased gastrointestinal iron absorption and tissue iron deposition. The most common form of this disorder is HFE-related HH, nearly always caused by homozygosity for the C282Y mutation.
Robert E, Fleming +4 more
openaire +2 more sources
Hematology, 2013 Hereditary hemochromatosis is an autosomal recessive disorder that disrupts the body's regulation of iron. It is the most common genetic disease in whites. Men have a 24-fold increased rate of iron-overload disease compared with women. Persons who are homozygous for the HFE gene mutation C282Y comprise 85 to 90 percent of phenotypically affected ...
Brian K, Crownover, Carlton J, Covey
openaire +5 more sources