Results 41 to 50 of about 113,339 (205)

Pathophysiological consequences and benefits of HFE mutations: 20 years of research

Haematologica, 2017
Mutations in the HFE (hemochromatosis) gene cause hereditary hemochromatosis, an iron overload disorder that is hallmarked by excessive accumulation of iron in parenchymal organs. The HFE mutation p.Cys282Tyr is pathologically most relevant and occurs in
Ina Hollerer, André Bachmann, Martina U. Muckenthaler   +2 more
doaj   +1 more source

Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva‐Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe‐Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba   +10 more
wiley   +1 more source

Molecular pathogenesis of hereditary hemochromatosis [PDF]

, 2016
. Hereditary hemochromatosis (HH) is an inherited iron overload disorder characterized by normal iron-driven erythropoiesis and abnormal iron metabolism, leading to excess iron deposited in parenchymal cells of liver, heart, and endocrine glands ...
Abdullahi, Mohamud Abukar Haji, Jiang, Chunmeng, Liu, Jingqi, Pu, Chunwen, Lang, Lang, Qiao, Liang   +5 more
core   +1 more source

Discrepancy between Serum Ferritin and Liver Iron Concentration in a Patient with Hereditary Hemochromatosis – The Value of T2* MRI

Case Reports in Oncology, 2020
Primary hemochromatosis is an inherited disorder, and the homeostatic iron regulator (HFE) gene C282Y mutation is a common cause of hemochromatosis in Europe. We are reporting a case of a 56-year-old female known to have hemochromatosis with the HFE gene
Mustafa A. Al-Tikrity, Mohamed A. Yassin
doaj   +1 more source

Mid‐upper arm circumference, steatosis indices, and elastography for screening liver steatosis in children with overweight/obesity: A prospective cross‐sectional study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Metabolic dysfunction–associated steatotic liver disease (MASLD) is common in children, and practical screening approaches are needed in populations with overweight/obesity. We aimed to evaluate mid‐upper arm circumference (MUAC) as a simple marker for ultrasonography (US)‐detected liver steatosis (LS) in children with overweight ...
Selcuk Teke, Tugba Cavis, Yasin Maruf Ergen, Birce Izgi Akcay, Edibe Gozde Basaran, Necati Balamtekin   +5 more
wiley   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

JPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder, Naomi Laventhal, Raja Rabah, Jacqueline Meadow   +3 more
wiley   +1 more source

Eligibility and Exclusion of Hemochromatosis Patients as Voluntary Blood Donors

Canadian Journal of Gastroenterology, 1998
BACKGROUND: Hereditary hemochromatosis patients are excluded in many countries as voluntary blood donors. In 1991, changes in the Canadian Red Cross policy allowed healthy hemochromatosis patients to become voluntary donors.
M Levstik, PC Adams
doaj   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

Circulating Omega‐3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank

Lipids, EarlyView.
ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley   +1 more source

DIFFERENT GENETIC FORMS OF HEREDITARY HEMOCHROMATOSIS IN AZERBAIJAN POPULATION

, 2020
Hemochromatoses are genetically determined or acquired forms of pathology due to excess iron in the organism [1,2,3]. There are primary and secondary forms of hemo­chromatosis.
Tahira Askarova
core   +1 more source