Results 51 to 60 of about 10,302 (227)

Estudi de les mutacions dels exons 2 i 4 del gen HFE en pacients amb porfiria cutània tarda esporàdica [PDF]

, 2006
[cat] La Porfíria Cutània Tarda (PCT) és una malaltia metabòlica que afecta a la pell i al fetge i que és desencadenada per la interacció de múltiples factors que inclouen l´herència, l´alcohol, el VHC, els estrògens i alguns agents tòxics, entre d ...
Toll Abelló, Agustí
core  

Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. [PDF]

, 2002
As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. beta-2-microglobulin (beta2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is ...
Friedrich Priem, Priem, F, Kaufmann, Stefan HE, Collins, Helen L, Ulrich E. Schaible, Kaufmann, S H E, Schaible, Ulrich E, Helen L. Collins, Collins, H L, Priem, Friedrich, Stefan H.E. Kaufmann, Schaible, U E   +11 more
core   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

An unusual presentation of seborrheic keratoses in a man with hereditary hemochromatosis [PDF]

, 2017
Hereditary hemochromatosis is an autosomalrecessive disorder that disturbs iron metabolismand results in iron deposition throughout the body.Iron accumulation in various organs may cause awide range of systemic symptoms and cutaneousmanifestations of the
Loh, Tiffany Y, Cohen, Philip R
core   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Non-HFE hemochromatosis

Revista Brasileira de Hematologia e Hemoterapia, 2012
Hereditary hemochromatosis (HH) is an autosomal recessive disorder classically related to HFE mutations. However, since 1996, it is known that HFE mutations explain about 80% of HH cases, with the remaining around 20% denominated non-HFE hemochromatosis.
Paulo Caleb Júnior de Lima Santos, Carla Luana Dinardo, Rodolfo Delfini Cançado, Isolmar Tadeu Schettert, José Eduardo Krieger, Alexandre Costa Pereira   +5 more
doaj   +1 more source

Developmental Trends in Serum Iron, Transferrin, and Transferrin Saturation From Birth to 12 Months

Acta Paediatrica, EarlyView.
ABSTRACT Aim There is a need for updated reference intervals for iron status biomarkers during infancy. This study aimed to investigate reference interval trends and diurnal variation of iron, transferrin, and transferrin saturation in infants subjected to delayed cord clamping at birth (DCC). Methods Data analysis from population‐based Swedish studies,
Sara Marie Larsson, Lena Hellström‐Westas, Ulrica Askelöf, Cecilia Götherström, Magnus Domellöf, Ola Andersson   +5 more
wiley   +1 more source

Chronic hepatitis B complicated with secondary hemochromatosis was cured clinically: A case report

Open Medicine, 2023
Chronic hepatitis B (CHB) often causes iron overload in the liver but rarely causes severe secondary hemochromatosis (SH). A 48-year-old man was infected with CHB via vertical transmission. For 21 years, nonstandard treatment with second-line hepatitis B
Ye Yun, Xie Jing, Wang Lina, He Cong, Tan Youwen   +4 more
doaj   +1 more source

A Successful Living Donor Liver Transplantation Using Hepatic Iron Deposition Graft Suspected by Magnetic Resonance Imaging

Case Reports in Transplantation, 2023
Recently, magnetic resonance imaging (MRI) has been developed as a widely available and noninvasive method for detecting and evaluating hepatic iron overload.
Nobuhiko Kurata, Masato Shizuku, Kanta Jobara, Yoji Ishizu, Masatoshi Ishigami, Yasuhiro Ogura   +5 more
doaj   +1 more source

Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia

European Journal of Haematology, EarlyView.
ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco, Diane S. Krause, Sara T. Olalla Saad   +2 more
wiley   +1 more source