Results 111 to 120 of about 10,302 (227)

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang, Yizhi Ge, Hongguang Xiang, Ji Liu, Yu Tian, Yan Shen, Dan Zong   +6 more
wiley   +1 more source

Examining the Clinical Use of Hemochromatosis Genetic Testing

Canadian Journal of Gastroenterology and Hepatology, 2015
BACKGROUND: Hereditary hemochromatosis leads to an increased lifetime risk for end-organ damage due to excess iron deposition. Guidelines recommend that genetic testing be performed in patients with clinical suspicion of iron overload accompanied by ...
Matthew B Lanktree, Bruce B Lanktree, Guillaume Paré, John S Waye, Bekim Sadikovic, Mark A Crowther   +5 more
doaj   +1 more source

Conversion to LCP Tacrolimus Mitigates Calcineurin‐Induced Nephrotoxicity in Patients After Liver Transplantation

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Background Calcineurin inhibitor (CNI)‐induced nephrotoxicity after liver transplantation (LT) is linked to increased morbidity and mortality. LCPT offers a particular extended‐release formulation, potentially improving the concentration‐dose (C/D) ratio and renal outcomes.
Maximilian Joseph Brol, Isabella Munske, Iyad Kabar, Philipp Stephan Althaus, Wenyi Gu, Frank Erhard Uschner, Michael Praktiknjo, Martin Sebastian McCoy, Kai‐Henrik Peiffer, Florian Rennebaum, Philipp Houben, Andreas Pascher, Hartmut H Schmidt, Jonel Trebicka, Tina Schomacher, Anna Hüsing‐Kabar   +15 more
wiley   +1 more source

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

, 2010
In the late 1800s, hemochromatosis was considered an odd autoptic finding. More than a century later, it was finally recognized as a hereditary, multi-organ disorder associated with a polymorphism that is common among white people: a 845G -> A change in ...
Antonello Pietrangelo, PIETRANGELO, Antonello   +1 more
core   +1 more source

HEREDITARY HEMOCHROMATOSIS: A RARE DISEASE OR A DIFFICULT DIAGNOSIS FOR A GENERAL PRACTITIONER?

Медицина в Кузбассе
Hemochromatosis is a hereditary disease belonging to the group of storage diseases characterized by impaired iron metabolism with its pathological accumulation in vital organs, including the liver.
Александра Валерьевна Морозова, Ольга Александровна Морозова, Николай Андреевич Бичан   +2 more
doaj  

Deferoxamine Improves Radiation‐Induced Peripheral Neuropathy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Radiation‐induced peripheral neuropathy (RIPN) is a devastating sequela of radiation therapy (XRT). Current treatment options are limited. Deferoxamine (DFO) has been useful in treating radiation‐induced dermal fibrosis. This study aimed to evaluate DFO for RIPN. Thus, 18 mice received 30Gy of fractionated XRT.
Christopher V. Lavin, Alexander Z. Fazilat, Carter B. Kendig, Palca Shibale, Kelly X. Huang, Sriya Nemani, Jennifer B. Parker, Caleb Valencia, Naga A. R. Ailury, Michelle Griffin, Arash Momeni, Michael T. Longaker, Derrick C. Wan   +12 more
wiley   +1 more source

Hepatitis B Surface Antigen Loss and Improved Clinical Outcomes in US Individuals With Chronic Hepatitis B Virus Infection

Journal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Hepatitis B surface antigen (HBsAg) loss is associated with improved clinical outcomes in patients with chronic hepatitis B virus (HBV) infection based on studies predominantly in Asian populations. We assessed real‐world associations between HBsAg loss and long‐term clinical outcomes in a diverse US population with chronic HBV infection. This
Myriam Drysdale, Rose Chang, Shuang Wang, Anna Coutinho, Vera Gielen, Theo Man, Rui Song, Mei Sheng Duh, Mandana Khalili, Dickens Theodore   +9 more
wiley   +1 more source

Fibrotic NASH Index (FNI) Is Associated with Long‐Term Mortality in Individuals with Type 2 Diabetes and MASLD

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aim Metabolic dysfunction‐associated steatotic liver disease (MASLD) frequently coexists with type 2 diabetes (T2D) and increases cardiovascular disease (CVD) risk, with hepatic fibrosis being the main determinant of mortality.
Ilaria Barchetta, Flavia Agata Cimini, Sara Dule, Giulia Passarella, Alessandro Oldani, Maria Neve Hirsch, Marta Cirelli, Marta Alfano, Maria Gisella Cavallo   +8 more
wiley   +1 more source

A patient with hereditary hemochromatosis, ulcerative colitis, and primary sclerosing cholangitis: genetic aspects

, 2001
This report describes a family in which the rare combination of hereditary hemochromatosis, ulcerative colitis and primary sclerosing cholangitis was found.
Pieter C.F. Stokkers, Cyriel Y. Ponsioen, Guido N.J. Tytgat, Sander J.H. van Deventer, van Deventer, S. J., Ann R. vd Horst, Stokkers, P. C., Ponsioen, C. Y., Tytgat, G. N., van der Horst, A. R.   +9 more
core   +1 more source

Bronze Diabetes in Congenital Dyserythropoietic Anemia Type 2: A Case Report

Journal of Diabetology
Secondary diabetes is caused by endocrine, pancreatic or hereditary disorders or certain medications which affect insulin secretion or action or both.
Samuel Sathweek Rayapati, Varun Damle, Sengottuvel Kayalvizhi, Ranjit Unnikrishnan, Viswanathan Mohan   +4 more
doaj   +1 more source