Results 121 to 130 of about 15,219 (276)
Hepatic iron overload, a hallmark of hereditary hemochromatosis, triggers progressive liver disease. There is also increasing evidence for a pathogenic role of iron in non-alcoholic fatty liver disease (NAFLD), which may progress to non-alcoholic ...
John Wagner+7 more
doaj +1 more source
Skew group algebras of piecewise hereditary algebras are piecewise hereditary [PDF]
We show that the main results of Happel-Rickard-Schofield (1988) and Happel-Reiten-Smalo (1996) on piecewise hereditary algebras are coherent with the notion of group action on an algebra. Then, we take advantage of this compatibility and show that if G is a finite group acting on a piecewise hereditary algebra A over an algebraically closed field ...
arxiv
HFE variants and the expression of iron-related proteins in breast cancer-associated lymphocytes and macrophages [PDF]
Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264664/The association of HFE (High Iron FE) major variants with breast cancer risk and behavior has been a matter of discussion for a long time. However, their impact on the expression of iron-
A Waheed+42 more
core +1 more source
Symmetric quasi-hereditary envelopes [PDF]
We show how any finite-dimensional algebra can be realized as an idempotent subquotient of some symmetric quasi-hereditary algebra. In the special case of rigid symmetric algebras we show that they can be realized as centralizer subalgebras of symmetric quasi-hereditary algebras.
arxiv
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis [PDF]
Mutations in hemojuvelin (HJV) are the most common cause of the juvenile-onset form of the iron overload disorder hereditary hemochromatosis. The discovery that HJV functions as a co-receptor for the bone morphogenetic protein (BMP) family of signaling ...
Babitt, Jodie L.+2 more
core +2 more sources
A note on distance-hereditary graphs whose complement is also distance-hereditary [PDF]
Distance-hereditary graphs are known to be the graphs that are totally decomposable for the split decomposition. We characterise distance-hereditary graphs whose complement is also distance-hereditary by their split decomposition and by their modular decomposition.
arxiv
Long-term survival in patients with hereditary hemochromatosis [PDF]
Claus Niederau+5 more
openalex +1 more source
The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression [PDF]
Hemochromatosis is caused by mutations in HFE, a protein that competes with transferrin (TF) for binding to transferrin receptor 1 (TFR1). We developed mutant mouse strains to gain insight into the role of the Hfe/Tfr1 complex in regulating iron ...
Andrews, Nancy C.+4 more
core +2 more sources
Hemochromatosis and Heart Involvement
Hemochromatosis is a life-threatening condition if left untreated, that is caused by excess iron in the body. It can be primary (hereditary) hemochromatosis, resulting from genes mutations, and secondary (acquired) as a result of excessive intake of iron
E. V. Reznik+3 more
doaj +1 more source
IntroductionHereditary hemochromatosis (HH) is an autosomal recessive disorder caused by mutations in the HFE gene, which increase intestinal iron absorption.
Paolo Agostinis+8 more
doaj +1 more source