Results 41 to 50 of about 713 (172)
Glycan Engineering for Cell and Developmental Biology [PDF]
, 2016 Cell-surface glycans are a diverse class of macromolecules that participate in many key biological processes, including cell-cell communication, development, and disease progression.
Griffin, Matthew E. +1 more
core +1 more source
Journal of Children's Orthopaedics, 2021 Purpose The aim of this study was to identify risk factors for ankle valgus in children with hereditary multiple exostoses (HME). Methods We retrospectively reviewed the medical records of patients with HME who were examined at our hospital between 2010 ...
Wanglin Zhang +3 more
doaj +1 more source
Hereditary multiple exostoses and solitary osteochondroma associated with growth hormone deficiency: to treat or not to treat? [PDF]
, 2015 BACKGROUND: Osteochondroma generally occurs as a single lesion and it is not a heritable disease. When two or more osteochondroma are present, this condition represents a genetic disorder named hereditary multiple exostoses (HME).
A Longhi +29 more
core +1 more source
Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier [PDF]
, 2022 In this study, the effect of heterozygous germline mutations in the heparan sulfate (HS) glycosaminoglycan chain co-polymerases EXT1 and EXT2 on glomerular barrier function and the endothelial glycocalyx in humans is investigated.
Baelde, H.J. +7 more
core +2 more sources
Medicina, 2022 Background and Objectives: Hereditary multiple exostoses (HME) is a disease characterized by cartilage-capped bony protuberances at the site of growth plates of long bones.
Muhammad Ajmal +5 more
doaj +1 more source
Rare Case Report: Chondrosarcoma Arising from Osteochondroma in MHE patient. [PDF]
, 2015 This is a unique case of chondrosarcoma. From this case, we learn that, Multiple Hereditary Exostoses have strong connection with familial bond. This disease has male predominance, but in this case, the family don’t have any son, and the father are ...
Hartanta, Sutiansi +1 more
core +3 more sources
A 40‐Year‐Old Male Presenting with Hereditary Multiple Exostosis: Management and Considerations
Case Reports in Orthopedics, Volume 2019, Issue 1, 2019., 2019 Hereditary multiple exostosis is a rare condition in which numerous benign osteochondromas form throughout the body, typically in areas of high bone turnover such as the metaphyseal plates of long bones. While many of these lesions remain clinically asymptomatic, other growth locations can lead to excruciating pain, limit a joint’s range of motion, and
Matthew Wells +2 more
wiley +1 more source
Low‐Grade Chondrosarcoma of the Proximal Phalanx: A Rare Presentation
Case Reports in Orthopedics, Volume 2019, Issue 1, 2019., 2019 Case. Chondrosarcomas are the second most common primary malignant sarcoma of the bone, though it is overall a rare tumor. Our case presents a 36‐year‐old Caucasian male who complained of an enlarging mass at his third finger MCP joint. After assessing the full clinical scenario, it was determined that wide excision with ray resection would provide the
Paul Knapp +3 more
wiley +1 more source
Two cases of asymptomatic rib exostosis treated by prophylactic surgical excision
Journal of Pediatric Surgery Case Reports, 2017 Exostosis is one of the most common benign bone lesions. It could be a solitary lesion or multiple lesions presented as part of HME. This condition often affects the metaphyseal region of long bones, including femur, tibia, humerus and ribs.
Kenichi Maeda +11 more
doaj +1 more source
Difficulties of Management of Multiple Synchronous Bone Tumors in Li‐Fraumeni Syndrome
Case Reports in Orthopedics, Volume 2019, Issue 1, 2019., 2019 Li‐Fraumeni syndrome is a rare inherited disease characterized by the early onset of multiple primary malignant tumors. Sarcomas account for more than 30% of all malignant tumors occurring at pediatric age. Furthermore, it was shown that the rates of second cancer were higher in childhood cancer survivors.
Marine Huby +6 more
wiley +1 more source