Results 151 to 160 of about 28,039 (211)

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Concept of neuroendocrine neoplasms of all organs with a focus on grading, subtyping. [PDF]

Virchows Arch
Kasajima A, Perren A, Klöppel G.
europepmc   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, EarlyView.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

Immune interception in cancer: prioritizing vaccination in high-risk and premalignant settings. [PDF]

Front Immunol
Zhang Q, Wang L, Ze L, Wei T, Zhang W.
europepmc   +1 more source

Breast Angiosarcoma: 15‐Years Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Breast angiosarcoma is a rare, aggressive malignancy that can be primary (PAS) or secondary (SAS). This study evaluates the management and outcomes of breast angiosarcoma in a single‐center breast/surgical oncology unit. Methods A retrospective review was conducted on patients with histologically confirmed PAS or SAS who underwent ...
Gaik Si Quah, Christopher Pyke, Christopher Allan   +2 more
wiley   +1 more source

The Vital Role of Family Physicians in the Screening and Early Detection of Lynch Syndrome: A Case Report. [PDF]

Cureus
Campelos J, Gomes M, Campos A, Cardoso M, Lopes M.   +4 more
europepmc   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Women's health across the reproductive lifespan in women with germline TP53 pathogenic variants: a clinical perspective. [PDF]

Oncologist
Halpern N, Bernstein-Molho R, Peerless Y, Kventsel I, Frenkel Z, Mizrachi Y, Shani H, Safrai M.   +7 more
europepmc   +1 more source