Results 11 to 20 of about 28,039 (211)
Cutaneous Expression of Familial Cancer Syndromes
Acta Dermato-Venereologica, 2021 Genodermatoses are inherited syndromes with cutaneous manifestations. Some genodermatoses are associated with malignancy of internal organs and tissues.
Anne-Johanne Andersen +3 more
doaj +1 more source
Hereditary colorectal cancer: genetics and screening diagnostics
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018 Aim of review. To present the data on main forms of hereditary colorectal cancer (CRC) and to discuss issues of its diagnostics, genetic testing and patient management. Summary.
O. I. Kit +6 more
doaj +1 more source
Familial Pancreatic Cancer and the Future of Directed Screening
Gut and Liver, 2017 Pancreatic cancer (PC) is the third most common cause of cancer-related death in the United States and the 12th most common worldwide. Mortality is high, largely due to late stage of presentation and suboptimal treatment regimens. Approximately 10% of PC
Sara Welinsky, Aimee L. Lucas
doaj +1 more source
Safety and efficacy of chemoprevention for familial adenomatous polyposis: a systematic review and meta-analysis [PDF]
Annals of ColoproctologyPurpose Familial adenomatous polyposis is a hereditary condition that predisposes individuals to colorectal cancer. This study aimed to evaluate the efficacy and safety of pharmacological therapies for reducing polyp number, burden, and size in ...
Francisco Tustumi +8 more
doaj +1 more source
Increased risk for uterine cancer among first-degree relatives to Swedish gastric cancer patients
Hereditary Cancer in Clinical Practice, 2020 Purpose In order to further understand genetically predisposing factors of gastric cancer, a retrospective study on 107 patients with gastric cancer was conducted.
Johanna Samola Winnberg +7 more
doaj +1 more source
Reed’s Syndrome: A Rare Systemic Genodermatosis
Gazeta Médica, 2023 Reed’s syndrome is an autosomal dominant rare genodermatosis, characterized by the presence of multiple cutaneous and uterine leiomyomatosis. This syndrome can be associated with renal cell carcinoma and leiomyosarcoma.
Madalena Braga +4 more
doaj
Additional germline findings from a tumor profiling program
BMC Medical Genomics, 2018 Background Matched tumor-normal sequencing, applied in precision cancer medicine, can identify unidentified germline Medically Actionable Variants (gMAVS) in cancer predisposition genes. We report patient preferences for the return of additional germline
Neda Stjepanovic +17 more
doaj +1 more source
Urological cancer related to familial syndromes
International Brazilian Journal of UrologyCancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been identified to be related to genetic syndromes in the last years with the advent of new molecular ...
Walter Henriques da Costa +2 more
doaj +1 more source
Metastatic follicular thyroid cancer in a patient with Birt‐Hogg‐Dubé syndrome
Clinical Case Reports, 2021 Birt‐Hogg‐Dubé syndrome (BHDS) is an extremely rare genetic condition that predisposes to renal cell carcinoma. This case describes a novel case of a patient with BHDS who also develops follicular thyroid cancer.
Elisa K. Bongetti +3 more
doaj +1 more source
Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal
HemaSphere, 2021 Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Peter Valent +39 more
doaj +1 more source