Results 81 to 90 of about 3,106 (209)

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Nonprogressive type II hereditary sensory autonomic neuropathy: a homogeneous clinicopathologic entity.

, 1992
Two different clinical subtypes were previously identified within hereditary sensory autonomic neuropathy (HSAN) type II: a stable congenital form and a progressive one. This paper discusses two clinicopathologic cases of nonprogressive HSAN type II with
Gerard Ferrière, Philippe Evrard, Kulakowski, S, Francesco Guzzetta, Guzzetta, F., Sophie Kulakowski, Ferrière, G, Evrard, Philippe   +7 more
core   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou, Christoforos K. Travlos, Lucas Lage Marinho, Thomas A. Mavrakanas, João Pedro Ferreira, Abhinav Sharma   +5 more
wiley   +1 more source

Determinant Factors of Self‐Care Deficit in People With Chronic Wounds: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and synthesise the scientific evidence on determinants of self‐care deficits in people with chronic wounds. Design Scoping review based on the Joanna Briggs Institute guidelines. Methods This scoping review was conducted by a review team responsible for study screening, data extraction and synthesis.
Janislei Soares Dantas, Yan Lincoln Mamede Gomes, Ana Clara de Macedo Farias Ramos, Selene Cordeiro Vasconcelos, Maria Eliane Moreira Freire   +4 more
wiley   +1 more source

Asymptomatic Carrier Neurologic Assessment: A Tool for Early Detection of Symptomatic Transition in Pathogenic TTR Gene Variant Carriers. [PDF]

Eur J Neurol
There are no tools to support early detection of ATTRv signs/symptoms or to identify risk of transition to clinically detectable disease in carriers of pathogenic ATTRv variants. This retrospective cohort study describes the ACNA, a brief 23‐item assessment for use in routine clinical visits.
Conceição I, González-Moreno J, Echaniz-Laguna A, Xiong K, Castaño A, Fox JC, Gillmore JD, Garcia-Pavia P, Reilly MM.   +8 more
europepmc   +2 more sources

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

Journal of Diabetes Investigation, EarlyView.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh, Abdulnabi T Alattar, Ahmed Abdul Karim Hassoun, Afaf Alshammary, Hussein Elbadawi, Khaled Aldossari, Noor Al Busaidi, Saud Alsifri, Talal Muzaffar, Wiam I. Hussein, Christine Talaat, Abanoub Effat, Marwa Elsaghier, Rayaz A Malik   +13 more
wiley   +1 more source

Disautonomia familiar: relato de caso. [PDF]

, 2001
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Usuy Junior, Eduardo Nobuyuki
core