Results 71 to 80 of about 2,341 (138)

Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease

Cells
Hepatocyte transplantation (HTx) combined with ex vivo gene therapy has garnered significant interest due to its potential for treating many inherited metabolic liver diseases.
Justin Gibson, Abishek Dhungana, Menam Pokhrel, Benjamin Arthur, Pramita Suresh, Olumide Adebayo, Renee N. Cottle   +6 more
doaj   +1 more source

Liver Transplant for Children With Hepatocellular Carcinoma and Hereditary Tyrosinemia Type 1.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2016
This study sought to determine the prevalence of hepatocellular carcinoma and other premalignant lesions in children with hereditary tyrosinemia type 1 who had undergone an orthotopic liver transplant at the Shiraz Transplant Center, in Shiraz, Iran.Between September 2006, and June 2011, thirty-six patients with hereditary tyrosinemia type 1 received a
Ali, Bahador, Seyed Mohsen, Dehghani, Bita, Geramizadeh, Saman, Nikeghbalian, Mohsen, Bahador, Seyed Ali, Malekhosseini, Kurosh, Kazemi, Heshmatolah, Salahi   +7 more
openaire   +1 more source

Clinical and para clinical findings in the children with tyrosinemia referring for liver transplantation

International Journal of Preventive Medicine, 2013
Background: Hereditary tyrosinemia type 1 (HT1) is a rare autosomal recessive inborn error of metabolism caused by deficiency of fumarylacetoacetate hydrolase enzyme.
Seyed Mohsen Dehghani, Mahmood Haghighat, Mohammad Hadi Imanieh, Hossein Karamnejad, Abdorrasoul Malekpour   +4 more
doaj  

Oxidative Stress, Glutathione Metabolism, and Liver Regeneration Pathways Are Activated in Hereditary Tyrosinemia Type 1 Mice upon Short-Term Nitisinone Discontinuation. [PDF]

Genes (Basel), 2020
Colemonts-Vroninks H, Neuckermans J, Marcelis L, Claes P, Branson S, Casimir G, Goyens P, Martens GA, Vanhaecke T, De Kock J.   +9 more
europepmc   +1 more source

SIADH as an Underrecognized Manifestation of Porphyria-like Crises in Hereditary Tyrosinemia Type 1: Clinical and Pathophysiological Insights. [PDF]

Int J Mol Sci
Saraceno E, Serra I, Bracci B, Pagliardini V, Pinon M, Tuli G, Versace A, Bondone C, Spada M.   +8 more
europepmc   +1 more source

In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1. [PDF]

Am J Case Rep
Bruno R, Donatelli S, Mastropasqua L, Nubile M.   +3 more
europepmc   +1 more source

An Unusual Case of Hereditary Tyrosinemia Type 1 and Bronchomalasia

The Journal of Tepecik Education and Research Hospital, 2007
Bülent Karapınar, Cem Karadeniz, Yasin Bulut, Esen Demir, Ayten Egemen, Mahmut Çoker   +5 more
openaire   +2 more sources

The Unique Spectrum of Mutations in Patients with Hereditary Tyrosinemia Type 1 in Different Regions of the Russian Federation. [PDF]

JIMD Rep, 2019
Baydakova GV, Ivanova TA, Mikhaylova SV, Saydaeva DK, Dzhudinova LL, Akhlakova AI, Gamzatova AI, Bychkov IO, Zakharova EY.   +8 more
europepmc   +1 more source

Hereditary Tyrosinemia Type 1 and Living Donor Liver Transplantation: Timing-Patient Selection-Complications

Turkiye Klinikleri Journal of Pediatrics, 2021
Altan ALİM, Mehmet Burak DAL, Yalçın ERDOĞAN, Ertuğrul KIYKIM, Necdet GÜLER, Ayşe Çiğdem AKTUĞLU ZEYBEK, Koray ACARLI   +6 more
openaire   +1 more source

In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1. [PDF]

Genetics
Rivest JF, Carter S, Goupil C, Antérieux P, Cyr D, Ung RV, Dal Soglio D, Mac-Way F, Waters PJ, Paganelli M, Doyon Y.   +10 more
europepmc   +1 more source