Results 111 to 120 of about 61,249 (214)

Generalized Stable Population and Agent-Based Models of Phenotypic Transmission in Human Populations, with an Application to Body Size. [PDF]

Hum Hered
Aldea N, García-Aguirre A, Beltrán-Sánchez H, Daza S, Palloni A.   +4 more
europepmc   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, EarlyView.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Prevalence and Risk Factors of Carbohydrate Metabolism Disorders among Pregnant Women in Kyrgyzstan. [PDF]

Iran J Public Health
Sultanalieva R, Zhunusova B, Knyazeva V, Abylova N, Sorokin A.   +4 more
europepmc   +1 more source

review marcatori genetici acquacoltura [PDF]

, 2012
Guarniero, Ilaria
core  

ROWVA: A Structure‐Based Metric for Predicting the Pathogenicity of Protein Variants Using Alphafold2

Cancer Science, EarlyView.
This study investigates whether several AF2‐derived scores can predict functional scores and pathogenicity labels, and suggests that the root mean square deviation between the wild‐type and variant structures predicted by AlphaFold2 (ROWVA) may be the most effective predictor. This approach may also be applicable to other multimeric proteins.
Taiki Furutani, Yuka Okusha, Hiroki Nagami, Hiroko Hanafusa, Shuta Tomida, Ryusuke Sawada, Yasuyuki Hosono, Masahiro Nakatochi   +7 more
wiley   +1 more source

Breeder turnover creates allelic variation in groups of gray wolves. [PDF]

Heredity (Edinb)
Ausband DE.
europepmc   +1 more source

BHCox: Bayesian heredity-constrained Cox proportional hazards models for detecting gene-environment interactions. [PDF]

BMC Bioinformatics
Sun N, Han Q, Wang Y, Sun M, Sun Z, Sun H, Shen Y.   +6 more
europepmc   +1 more source

Extreme weather and economic crisis in the 1430s in England, and the implications for tenurial change

The Economic History Review, EarlyView.
Abstract The 1430s were characterized by extreme weather conditions, food and fodder shortages, and high mortalities among animals and humans, although the severity of events and their consequences in England have received limited attention. The economic downturn and the depressed customary land market in this decade marked the beginning of the Great ...
Mark Bailey
wiley   +1 more source

Potential association of certain microRNA gene polymorphisms with recurrent pregnancy loss susceptibility in Saudi women. [PDF]

PLoS One
Rabaa A, Alkuriji A, Kabbi A, Almalki S, Almasawi Z, Daghestani M, Hakami H, Alzahrani J.   +7 more
europepmc   +1 more source

Redox environment modulates aggregation of ataxin‐3 in vitro — Implications for drug screening of cysteine‐rich proteins

The FEBS Journal, EarlyView.
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak, Martina Sollazzo, Elisa Monaca, Raffaele Sabbatella, Maria Agnese Morando, Oleg Chertkov, Laura Puglisi, Martina Mascellino, Anna Fricano, Sandra Macedo‐Ribeiro, Caterina Alfano   +10 more
wiley   +1 more source