Results 171 to 180 of about 61,249 (214)

Pediatric obesity and the risk of multiple sclerosis: a nationwide prospective cohort study. [PDF]

Int J Obes (Lond)
Hagman E, Putri RR, Danielsson P, Marcus C.   +3 more
europepmc   +1 more source

Why we age

Biological Reviews, Volume 101, Issue 2, Page 911-925, April 2026.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

Individuality Through Ecology: Rethinking the Evolution of Complex Life From an Externalist Perspective. [PDF]

Ecol Evol
Bourrat P, Takacs P, Doulcier G, Nitschke MC, Black AJ, Hammerschmidt K, Rainey PB.   +6 more
europepmc   +1 more source

Adverse Effects of Low Serum HDL‐C Levels on Prognosis and Tumor Immune Microenvironment in Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Disorders of lipid metabolism contribute to the occurrence and progression of hematological malignancies, including chronic lymp hocytic leukemia (CLL). The objective of this study was to investigate the association between serum lipid levels and prognosis in patients with CLL.
Weiran Lv, Shutong Liu, Jiangtao Song, Zhijian Liang, Huaze Liao, Qianqian Huang, Ziang Zhu, Zhoupei Mo, Yun Wang, Yang Liang   +9 more
wiley   +1 more source

Detection of positive selection on depression-associated genes. [PDF]

Heredity (Edinb)
Yang S, Zheng C, Xia C, Kang J, Gu L.
europepmc   +1 more source

Aicardi‐Goutières Syndrome Type 6: Case Report and Structural Prediction Supporting a Dominant‐Negative Effect of the ADAR1 c.3019G>A Variant

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Aicardi–Goutières syndrome type 6 (AGS6) is a genetically determined autoinflammatory disorder, classically inherited in an autosomal recessive manner. We report a Czech child with a heterozygous ADAR1 NM_001111.5:c.3019G>A variant causing AGS6.
Katerina Turan, Petra Pokorna, Kamila Rihova, Jana Kubatova, Katerina Kozelkova, Eliska Hlouskova, Pavlina Danhofer, Petr Jabandziev, Jiri Damborsky, Regina Demlova, Ondrej Slaby, Katerina Slaba   +11 more
wiley   +1 more source

A Family with Meester-Loeys Syndrome Caused by a Novel Missense Variant in the <i>BGN</i> Gene. [PDF]

Int J Mol Sci
Riancho JA, Vega AI, Del Real A, Sañudo C, Pérez-Castrillón JL, García-López R, Puente N, Nistal JF, Fernández-Luna JL.   +8 more
europepmc   +1 more source

PRKD3 Overexpression May Improve Survival and Suppresses Proliferation in Colorectal Cancer

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Objective The study aimed to explore PRKD3 protein expression in colorectal cancer and its clinical implications. Methods PRKD3 expression was assessed in 189 paired colorectal cancer tissues and their corresponding adjacent non‐cancerous counterparts using tissue microarray‐based immunohistochemistry. The associations of PRKD3 expression with
Bin Zhang, Chen Chang, Jingli Chen, Yue Cao, Yu Chang, Lele Liu, Wensheng Li, Guorong Wang   +7 more
wiley   +1 more source

Current status and advances in research on the impact and mechanisms of atmospheric pollutants on gastric cancer: a narrative review. [PDF]

Transl Cancer Res
Zhang C, Shao Q, Liu J, Zhang F, Li Y, Huang Z.   +5 more
europepmc   +1 more source

The Brain‐Gut Axis in Parkinson's Disease Pathology

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Exposure to environmental toxins induces gut dysbiosis, increases intestinal epithelial barrier permeability, immune activation, and oxidative stress, promoting α‐syn misfolding and propagation. Brainstem DMV neurons exhibit α‐syn pathology, dysregulating neuronal excitability and vagal control of GI functions.
Kudret Selin Ozkaya, Kirsteen N. Browning   +1 more
wiley   +1 more source