Results 1 to 10 of about 99,486 (214)
Boosting heritability: estimating the genetic component of phenotypic variation with multiple sample splitting [PDF]
BMC Bioinformatics, 2021 Background Heritability is a central measure in genetics quantifying how much of the variability observed in a trait is attributable to genetic differences.
The Tien Mai +2 more
doaj +2 more sources
Heritability curves: a local measure of heritability [PDF]
arXiv, 2020 This paper introduces a new measure of heritability which relaxes the classical assumption that the degree of heritability of a continuous trait can be summarized by a single number.This measure can be used in situations where the trait dependence structure between family members is nonlinear, in which case traditional mixed effects models and ...
Berentsen, Geir D. +4 more
arxiv +3 more sources
Heritability of Personality [PDF]
Psychological Topics, 2017 The aim of this study is to simplify the issue of the concept of heritability, to give an introduction to the behavioral genetic theory and methods, as well as to give an overview of the current knowledge about heritability of personality and the ...
Denis Bratko +2 more
doaj +6 more sources
Pediatric Neurology Briefs, 2000 A twin study design was used to examine the the genetic validity of attention deficit hypoeractivity disorder (ADHD)-related phenotypes.
J Gordon Millichap
doaj +3 more sources
Heritability in frontotemporal tauopathies
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019 Introduction Exploring the degree of heritability in a large cohort of frontotemporal lobar degeneration with tau‐immunopositive inclusions (FTLD‐tau) and determining if different FTLD‐tau subtypes are associated with stronger heritability will provide ...
Shelley L. Forrest +9 more
doaj +4 more sources
Optimal population size to detect quantitative trait loci in Korean native chicken: a simulation study [PDF]
Animal Bioscience, 2022 Objective A genomic region associated with a particular phenotype is called quantitative trait loci (QTL). To detect the optimal F2 population size associated with QTLs in native chicken, we performed a simulation study on F2 population derived from ...
Chiemela Peter Nwogwugwu +6 more
doaj +1 more source
Overall heritability in popcorn estimated by meta-analysis
Acta Scientiarum: Agronomy, 2021 The objective of this study was to conduct a meta-analysis and test its efficiency in summarizing the heterogeneous data of heritability estimates for the traits of grain yield (GY) and popping expansion (PE), and to provide reliable estimates of ...
Luiz Rafael Clóvis +6 more
doaj +1 more source
What does heritability of Alzheimer's disease represent?
PLoS ONE, 2023 IntroductionBoth late-onset Alzheimer's disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains to be discovered is debated.
Emily Baker +14 more
doaj +1 more source
Heritability estimation of osteoarthritis in the pig-tailed macaque (Macaca nemestrina) with a look toward future data collection [PDF]
PeerJ, 2014 We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC).
Peter B. Chi +3 more
doaj +2 more sources
On Negative Heritability and Negative Estimates of Heritability [PDF]
Genetics, 2017 Abstract We consider the problem of interpreting negative maximum likelihood estimates of heritability that sometimes arise from popular statistical models of additive genetic variation. These may result from random noise acting on estimates of genuinely positive heritability, but we argue that they may also arise from misspecification ...
Steinsaltz, David +2 more
openaire +6 more sources