High heritability is compatible with the broad distribution of set point viral load in HIV carriers. [PDF]
PLoS Pathogens, 2015 Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Sebastian Bonhoeffer +2 more
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What does heritability of Alzheimer's disease represent?
PLoS ONE, 2023 IntroductionBoth late-onset Alzheimer's disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains to be discovered is debated.
Emily Baker +14 more
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Overall heritability in popcorn estimated by meta-analysis
Acta Scientiarum: Agronomy, 2021 The objective of this study was to conduct a meta-analysis and test its efficiency in summarizing the heterogeneous data of heritability estimates for the traits of grain yield (GY) and popping expansion (PE), and to provide reliable estimates of ...
Luiz Rafael Clóvis +6 more
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Optimal population size to detect quantitative trait loci in Korean native chicken: a simulation study [PDF]
Animal Bioscience, 2022 Objective A genomic region associated with a particular phenotype is called quantitative trait loci (QTL). To detect the optimal F2 population size associated with QTLs in native chicken, we performed a simulation study on F2 population derived from ...
Chiemela Peter Nwogwugwu +6 more
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BMI heritability and its relationship with puberty in 6 – 18-year-old twins
Zhongguo gonggong weisheng, 2023 ObjectiveTo analyze the heritability of body mass index (BMI) and the impact of puberty on the heritability among twins aged 6 – 18 years in Shandong province.
Tingting GUO, Yunjie BAI, Aiping FAN
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Heritability estimation of osteoarthritis in the pig-tailed macaque (Macaca nemestrina) with a look toward future data collection [PDF]
PeerJ, 2014 We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC).
Peter B. Chi +3 more
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BMC Bioinformatics, 2021 Background Heritability is a central measure in genetics quantifying how much of the variability observed in a trait is attributable to genetic differences.
The Tien Mai +2 more
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Cancer cell lines show high heritability for motility but not generation time [PDF]
, 2020 Tumour evolution depends on heritable differences between cells in traits affecting cell survival or replication. It is well established that cancer cells are genetically and phenotypically heterogeneous; however, the extent to which this phenotypic ...
Butler, George +4 more
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Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. [PDF]
PLoS Genetics, 2013 Important knowledge about the determinants of complex human phenotypes can be obtained from the estimation of heritability, the fraction of phenotypic variation in a population that is determined by genetic factors.
Noah Zaitlen +6 more
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Genomic Heritability of Bovine Growth Using a Mixed Model [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 This study investigated heritability for bovine growth estimated with genomewide single nucleotide polymorphism (SNP) information obtained from a DNA microarray chip.
Jihye Ryu, Chaeyoung Lee
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