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On Negative Heritability and Negative Estimates of Heritability [PDF]
Genetics, 2017 Abstract We consider the problem of interpreting negative maximum likelihood estimates of heritability that sometimes arise from popular statistical models of additive genetic variation. These may result from random noise acting on estimates of genuinely positive heritability, but we argue that they may also arise from misspecification ...
Steinsaltz, David +2 more
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From the trajectory of heritability to the heritability of trajectories
Behavioral and Brain Sciences, 2021 Abstract Although compelling and insightful, the proposal by Uchiyama et al. largely neglects within-person change over time, arguably the central topic of interest within their framework. Longitudinal behavioural genetics modelling suggests that the heritability of trajectories is low, in contrast to high and increasing cross-sectional heritability
Rogier A. Kievit +2 more
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The heritability of attractiveness [PDF]
Current Biology, 2007 SummarySexual selection is responsible for the evolution of numerous conspicuous and extravagant displays observed in nature — from cricket choruses to peacock's tails. A key assumption of many models of sexual selection is that attractive males father attractive sons1.
Taylor, Michelle L. +2 more
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Cancer cell lines show high heritability for motility but not generation time [PDF]
, 2020 Tumour evolution depends on heritable differences between cells in traits affecting cell survival or replication. It is well established that cancer cells are genetically and phenotypically heterogeneous; however, the extent to which this phenotypic ...
Butler, George +4 more
core +2 more sources
Is Cladogenesis Heritable? [PDF]
Systematic Biology, 2002 The heritability of speciation rates and extinction risks is a crucial parameter in models of macroevolution, but little direct evidence has been available to assess the occurrence, strength, or generality of this heritability. We tested for heritability using correlations between ancestral and descendent branch lengths in phylogenetic trees, an ...
Arne Ø. Mooers +4 more
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Heritability of endometriosis [PDF]
Fertility and Sterility, 2015 To estimate the relative contribution of genetic influences and prevalence on endometriosis.Analysis of self-reported data from a nationwide population-based twin registry.Not applicable.A total of 28,370 women, female monozygotic (MZ) or dizygotic (DZ) twins, who participated in either of two surveys (1998-2002 or 2005-2006).None.Self-reported ...
Pia Svedberg +7 more
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Common DNA markers can account for more than half of the genetic influence on cognitive abilities [PDF]
, 2013 For nearly a century, twin and adoption studies have yielded substantial estimates of heritability for cognitive abilities, although it has proved difficult for genomewide-association studies to identify the genetic variants that account for this ...
Davis, OS +5 more
core +2 more sources
High Heritability Is Compatible with the Broad Distribution of Set Point Viral Load in HIV Carriers. [PDF]
, 2015 Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Bonhoeffer, S, Fraser, C, Leventhal, GE
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Estimates of genetic parameters of distal limb fracture and superficial digital flexor tendon injury in UK Thoroughbred racehorses [PDF]
, 2014 A retrospective cohort study of distal limb fracture and superficial digital flexor tendon (SDFT) injury in Thoroughbred racehorses was conducted using health records generated by the British Horseracing Authority (BHA) between 2000 and 2010.
Blott, Sarah C. +5 more
core +1 more source
Effect of body composition methodology on heritability estimation of body fatness [PDF]
, 2012 Heritability estimates of human body fatness vary widely and the contribution of body composition methodology to this variability is unknown. The effect of body composition methodology on estimations of genetic and environmental contributions to body ...
Bouchard, Thomas J. +11 more
core +1 more source