Omics GWAS: A Multi‐Omics Integrative Analysis Platform for Genome‐Wide Association Studies
Med Research, EarlyView.ABSTRACT With the rapid advancement of genome‐wide association studies (GWAS), downstream analyses of GWAS data have become essential for elucidating the genetic mechanisms that underlie complex diseases. However, current post‐GWAS analyses face numerous challenges, including heterogeneous data formats, challenges in multi‐omics integration, and ...
Xu Zhang +8 more
wiley +1 more source
Heritability of the <i>Pinus radiata</i> root microbiome. [PDF]
Front Plant SciGraham NJ +4 more
europepmc +1 more source
SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy
Movement Disorders, EarlyView.Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley +1 more source
Genetic modulation of yield and phenotypic plasticity of yield in winter wheat. [PDF]
J Exp BotGiordano N +16 more
europepmc +1 more source
Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome
Neurourology and Urodynamics, EarlyView.ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari +5 more
wiley +1 more source
Genetic influences on accelerometer-measured physical activity and sedentary time in children: sex-specific patterns from a Swedish twin study. [PDF]
Sci RepHelgadóttir B +5 more
europepmc +1 more source
Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley +1 more source
Genomic selection accuracy and bias using imputed genotypes on growth, welfare and fitness traits in two Pekin duck lines. [PDF]
BMC GenomicsMatika O +7 more
europepmc +1 more source
Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports
Pediatric Anesthesia, EarlyView.ABSTRACT Background Genetic mitochondrial diseases (GMDs) are a large group of genetically and clinically heterogeneous disorders caused by defects in genes encoding mitochondrial components. GMDs are grouped into named syndromes based on clinical presentation, for example, Leigh syndrome (LS).
Brittany M. Johnson, Simon C. Johnson
wiley +1 more source
People and Nature, EarlyView.Abstract Noise pollution is an environmental stressor negatively affecting humans and biodiversity. Noise pollution is often measured and regulated according to loudness, but in this study, we assessed noise pollution based on human perceptions of soundscapes.
Caren B. Cooper +3 more
wiley +1 more source