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Spatially Dense 3D Facial Heritability and Modules of Co-heritability in a Father-Offspring Design
Introduction: The human face is a complex trait displaying a strong genetic component as illustrated by various studies on facial heritability. Most of these start from sparse descriptions of facial shape using a limited set of landmarks.
Hanne Hoskens +15 more
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A twin study design was used to examine the the genetic validity of attention deficit hypoeractivity disorder (ADHD)-related phenotypes.
J Gordon Millichap
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Estimating the heritability of psychological measures in the Human Connectome Project dataset.
The Human Connectome Project (HCP) is a large structural and functional MRI dataset with a rich array of behavioral and genotypic measures, as well as a biologically verified family structure. This makes it a valuable resource for investigating questions
Yanting Han, Ralph Adolphs
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Heritability of scoliosis [PDF]
To estimate the heritability of scoliosis in the Swedish Twin Registry.Self-reported data on scoliosis from 64,578 twins in the Swedish Twin Registry were analysed. Prevalence, pair- and probandwise concordances and tetrachoric correlations in mono- and dizygotic same-sex twins were calculated. The relative importance of genetic variance, i.e.
Anna, Grauers +2 more
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On the heritability of geographic range sizes [PDF]
Within taxonomic groups, most species are restricted in their geographic range sizes, with only a few being widespread. The possibility that species-level selection on range sizes contributes to the characteristic form of such speciesrange size ...
Gaston, K.J., Webb, T.J.
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Genomic Heritability of Bovine Growth Using a Mixed Model [PDF]
This study investigated heritability for bovine growth estimated with genomewide single nucleotide polymorphism (SNP) information obtained from a DNA microarray chip.
Jihye Ryu, Chaeyoung Lee
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Introduction Depression shows a moderate heritability of 37-42%, which can be up to 75% in severely depressed samples 75%. At the same time SNP-based heritability of depression in GWAS-s is around 8-9%.
X. Gonda +6 more
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Depigmented wing patch size is a condition-dependent indicator of viability in male collared flycatchers [PDF]
Honesty of sexual advertisement is thought to be the result of signalling costs. Because production costs of depigmented plumage patches are probably very low, their role as honest signals of individual quality has been questioned. Costs of bearing these
Garamszegi, László Zsolt +2 more
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Multiple testing correction in linear mixed models. [PDF]
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar +3 more
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Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.
For most complex traits, results from genome-wide association studies show that the proportion of the phenotypic variance attributable to the additive effects of individual SNPs, that is, the heritability explained by the SNPs, is substantially less than
Sven Stringer +4 more
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