Results 21 to 30 of about 108,348 (283)

Genetics of callous-unemotional behavior in children.

PLoS ONE, 2013
Callous-unemotional behavior (CU) is currently under consideration as a subtyping index for conduct disorder diagnosis. Twin studies routinely estimate the heritability of CU as greater than 50%. It is now possible to estimate genetic influence using DNA
Essi Viding, Thomas S Price, Sara R Jaffee, Maciej Trzaskowski, Oliver S P Davis, Emma L Meaburn, Claire M A Haworth, Robert Plomin   +7 more
doaj   +1 more source

Trait heritability in major transitions

BMC Biology, 2018
Background Increases in biological complexity and the origins of life’s hierarchical organization are described by the “major transitions” framework.
Matthew D. Herron, Seyed A. Zamani-Dahaj, William C. Ratcliff   +2 more
doaj   +1 more source

Heritability of plant height and head diameter in sunflower (Helianthus annuus L.) [PDF]

Ratarstvo i Povrtarstvo, 2013
Purpose of this study was to estimate heritability, in broad and narrow sense, for sunflower plant height and head diameter in order to evaluate success of selection of these traits. Fifteen sunflower populations were evaluated.
Jocković Milan, Jocić Siniša, Marinković Radovan, Prodanović Slaven, Čanak Petar, Ćirić Mihajlo, Mitrović Petar   +6 more
doaj   +1 more source

Heritability Estimated Using 50K SNPs Indicates Missing Heritability Problem in Holstein Breeding [PDF]

Genomics & Informatics, 2015
Previous studies in Holstein have shown 35% to 51.8% heritability in milk production traits, such as milk yield, fat, and protein, using pedigree data.
Donghyun Shin, Kyoung-Do Park, Sojoeng Ka, Heebal Kim, Kwang-hyeon Cho   +4 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Heritability of apolipoprotein (a) traits in two-generational African-American and Caucasian families[S]

Journal of Lipid Research, 2019
Heritability of LPA allele, apo(a) isoform sizes, and isoform-associated lipoprotein(a) [Lp(a)] levels was studied in 82 Caucasian and African-American families with two parents and two children (age: 6–74 years).
Byambaa Enkhmaa, Erdembileg Anuurad, Wei Zhang, Kyoungmi Kim, Lars Berglund   +4 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Heritability of Personality

Psychological Topics, 2017
The aim of this study is to simplify the issue of the concept of heritability, to give an introduction to the behavioral genetic theory and methods, as well as to give an overview of the current knowledge about heritability of personality and the ...
Denis Bratko, Ana Butković, Tena Vukasović Hlupić   +2 more
doaj   +2 more sources

Lobular Difference in Heritability of Brain Atrophy among Elderly Japanese: A Twin Study

Medicina, 2022
Background and Objectives: Brain atrophy is related to cognitive decline. However, the heritability of brain atrophy has not been fully investigated in the Eastern Asian population.
Soichiro Saeki, Helga Szabo, Rie Tomizawa, Adam D. Tarnoki, David L. Tarnoki, Yoshiyuki Watanabe, Osaka Twin Research Group, Chika Honda   +7 more
doaj   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source