Results 41 to 50 of about 99,486 (214)

High heritability is compatible with the broad distribution of set point viral load in HIV carriers. [PDF]

open access: yesPLoS Pathogens, 2015
Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Sebastian Bonhoeffer   +2 more
doaj   +1 more source

SumVg: Total heritability explained by all variants in genome-wide association studies based on summary statistics with standard error estimates [PDF]

open access: yesarXiv, 2023
Genome-wide association studies (GWAS) are commonly employed to study the genetic basis of complex traits and diseases, and a key question is how much heritability could be explained by all variants in GWAS. One widely used approach that relies on summary statistics only is LD score regression (LDSC), however the approach requires certain assumptions ...
arxiv  

SNP-based and pedigree-based estimation of heritability and maternal effect for body weight traits in an F2 intercross between Landrace and Jeju native black pigs

open access: yesJournal of Animal Reproduction and Biotechnology, 2016
Growth traits, such as body weight, directly influence productivity and economic efficiency in the swine industry. In this study, we estimate heritability for body weight traits usinginformation from pedigree and genome-wide single nucleotide ...
Hee-Bok Park   +11 more
doaj   +1 more source

Heritability estimates of body size in fetal life and early childhood. [PDF]

open access: yesPLoS ONE, 2012
The objective was to estimate the heritability for height and weight during fetal life and early childhood in two independent studies, one including parent and singleton offsprings and one of mono- and dizygotic twins.This study was embedded in the ...
Dennis O Mook-Kanamori   +8 more
doaj   +1 more source

Lobular Difference in Heritability of Brain Atrophy among Elderly Japanese: A Twin Study

open access: yesMedicina, 2022
Background and Objectives: Brain atrophy is related to cognitive decline. However, the heritability of brain atrophy has not been fully investigated in the Eastern Asian population.
Soichiro Saeki   +7 more
doaj   +1 more source

Heritability of the limbic networks [PDF]

open access: yesSocial Cognitive and Affective Neuroscience, 2015
Individual differences in cognitive ability and social behaviour are influenced by the variability in the structure and function of the limbic system. A strong heritability of the limbic cortex has been previously reported, but little is known about how genetic factors influence specific limbic networks. We used diffusion tensor imaging tractography to
Budisavljevic   +15 more
openaire   +7 more sources

Heritability in friendship networks [PDF]

open access: yesSSRN Electronic Journal, 2020
AbstractFriendship networks account for a large part of an individual’s economic success or failure in life. Using data from the German TwinLife study, we explore, within a classical twin design, to which extent friendship networks are related to genes.
Selen Yildirim   +2 more
openaire   +3 more sources

Effect of inbreeding on performance and genetic parameters of growth and survival traits in the Pacific oyster Crassostrea gigas at larval stage

open access: yesAquaculture Reports, 2021
The occurrence of inbreeding over generations cannot be avoided in breeding practice because of limited effective population sizes, and inbreeding is expected to decrease the heritability within populations.
Jiafeng Fang, Ziqiang Han, Qi Li
doaj  

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC). [PDF]

open access: yesPLoS ONE, 2015
Blood pressure (BP) is a heritable trait with multiple environmental and genetic contributions, with current heritability estimates from twin and family studies being ~ 40%.
Elias Salfati   +3 more
doaj   +1 more source

Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective

open access: yesFrontiers in Genetics, 2020
Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many ...
Arthur Frouin   +6 more
doaj   +1 more source

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