Results 41 to 50 of about 169,399 (309)

The management of recurrent hiatal hernia: a single-center retrospective study

BMC Surgery
Purpose Hiatal hernia (HH), characterized by gastric mucosa displacement > 2 cm above the diaphragm, presents significant challenges with recurrence rates ranging from 10 to 60%.
Minxian Zhao, Xiaoli Liu, Haiyun Li, Yusheng Nie, Lei Guan, Ruotong Zheng, Yingmo Shen, Huiqi Yang   +7 more
doaj   +1 more source

Appendix in Inguinal Hernia—Amyand’s Hernia [PDF]

Indian Journal of Surgery, 2013
Inguinal hernia containing vermiform appendix as its content is termed as Amyand's hernia. Though an unusual condition, however it is important for the radiologists as well as the surgeons to be aware of this entity especially if the herniated appendix is inflamed so as to avoid delay in treatment and decrease the associated morbidity and mortality.
Aastha, Sagar, Jyoti, Sureka
openaire   +2 more sources

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Modified technique of extraperitoneal colostomy without incision of the posterior rectus sheath

Scientific Reports, 2021
Extraperitoneal colostomy is a widely used technique during abdominoperineal resection (APR) operation for lower rectal cancer. This technique has been reported to be effective to prevent the postoperative parastomal hernia in some retrospective studies,
Tao Zhang, Daye Yang, Gongping Sun, Dewei Zhang   +3 more
doaj   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

Analysis of operation procedure and effect for emergency surgery in general hospital during novel coronavirus pneumonia period

BMC Surgery, 2020
Background Novel coronavirus pneumonia (NCP) outbreak in Wuhan, China in early 2020, resulted in over 80 thousand infections in China. At present, NCP has an explosive growth in the world.
Yuchen Liu, Minggang Wang, Yingmo Shen, Jie Chen   +3 more
doaj   +1 more source

A protocol for developing core outcome sets for laparoscopic hiatal hernia repair

Trials, 2022
Background Hiatal hernias negatively damage patients’ health and life quality. Laparoscopic hiatal hernia repair is currently the gold standard for the treatment of hiatal hernia (LHHR).
Xiaoli Liu, Qiuyue Ma, Jie Chen, Huiqi Yang   +3 more
doaj   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Comparison of open and laparoscopic inguinal-hernia repair in octogenarians

Asian Journal of Surgery, 2023
Summary: Introduction: Although the advantages of laparoscopic inguinal hernia repair in the general population have been reported, its role in octogenarians has yet to be elucidated. This retrospective study was designed to compare the outcomes of open
Xiaoqiang Zhu, Zhengni Liu, Jianfeng Shen, Jiajie Liu, Rui Tang   +4 more
doaj   +1 more source

Essential Updates 2024–2026: Advances in Colorectal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Surgical innovation in colorectal cancer is increasingly judged not by technical feasibility alone, but by whether it improves oncological outcomes, preserves function, reduces morbidity, or makes difficult procedures more reproducible. This structured narrative review examines major surgical studies published from January 2024 through July ...
Hiroyasu Kagawa, Yusuke Kinugasa
wiley   +1 more source