Results 81 to 90 of about 178,763 (315)

Comparative proteome analysis of the ligamentum flavum of patients with lumbar spinal canal stenosis

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
This study investigated the pathology of thickened ligamentum flavum in patients with lumbar spinal canal stenosis (LSCS) based on protein expression levels using shotgun proteome analysis. The results showed that tissue repair via fibrosis, chondrometaplasia, and amyloid deposits may be important pathologies that occur in the thickened ligamentum ...
Yutaka Yabe, Yoshihiro Hagiwara, Masahiro Tsuchiya, Takashi Minowa, Taro Takemura, Shinya Hattori, Shinichirou Yoshida, Takahiro Onoki, Keisuke Ishikawa   +8 more
wiley   +1 more source

Abnormal DNA Methylation Profile Suggests the Extension of the Clinical Spectrum of the SETD2‐Related Disorders to a Syndromic Multiple Tumor Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain, Antonio Vitobello, Bekim Sadikovic, Juliette Albuisson, Léa Gaudillat, Martin Chevarin, Julien Maraval, Christel Thauvin‐Robinet, Jennifer Kerkhof, Christophe Philippe, Sophie Nambot, Laurence Faivre   +11 more
wiley   +1 more source

Influence of patient‐specific factors when comparing multifidus fat infiltration between chronic low back pain patients and asymptomatic controls

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
Many studies have attempted to link multifidus fat infiltration with muscle quality and chronic low back pain, but there is no consensus on these relationships. This study suggests that when the presence of fat is not characteristic of an individual's age, sex, and BMI, it may be a back pain risk factor.
Alexander M. Ballatori, Shane Shahrestani, Priya Nyayapati, Vibhu Agarwal, Roland Krug, Misung Han, Aaron J. Fields, Conor O'Neill, Sibel Demir‐Deviren, Jeffrey C. Lotz, Jeannie F. Bailey   +10 more
wiley   +1 more source

PHIMOSIS AND HERNIA. [PDF]

The Lancet, 1904
n ...
openaire   +6 more sources

Tall Stature and Scoliosis Associated With a Novel Homozygous Loss‐of‐Function Missense Variant in NPR3

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT NPR3‐related tall stature is characterized by tall stature, elongated big toes, and additional epiphyses in hand and foot bones. The condition is caused by biallelic loss‐of‐function variants affecting natriuretic peptide receptor 3 (NPR3). Five individuals from four different families have been reported.
Pierre Moffatt, Chantal Janelle, Valancy Miranda, Ghalib Bardai, Frank Rauch   +4 more
wiley   +1 more source

N‐acetylcysteine attenuates oxidative stress‐mediated cell viability loss induced by dimethyl sulfoxide in cryopreservation of human nucleus pulposus cells: A potential solution for mass production

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
N‐acetylcysteine attenuates DMSO induced oxidative stress mediated viability loss in NP cells. Abstract Background Cell therapy is considered a promising strategy for intervertebral disc (IVD) regeneration. However, cell products often require long‐term cryopreservation, which compromises cell viability and potency, thus potentially hindering ...
Shota Tamagawa, Daisuke Sakai, Jordy Schol, Kosuke Sako, Yoshihiko Nakamura, Erika Matsushita, Takayuki Warita, Soma Hazuki, Hidetoshi Nojiri, Masato Sato, Muneaki Ishijima, Masahiko Watanabe   +11 more
wiley   +1 more source

Correlation analysis between the changes in plasma ghrelin level and weight loss after sleeve gastrectomy combined with fundoplication

BMC Surgery
Background Laparoscopic sleeve gastrectomy combined with fundoplication (LSGFD) can significantly control body weight and achieve effective anti-reflux effects.
Xin Li, Aikebaier Aili, Aliyeguli Aipire, Pierdiwasi Maimaitiyusupu, Maimaitiaili Maimaitiming, Kelimu Abudureyimu   +5 more
doaj   +1 more source

Comparison of open and laparoscopic inguinal-hernia repair in octogenarians

Asian Journal of Surgery, 2023
Summary: Introduction: Although the advantages of laparoscopic inguinal hernia repair in the general population have been reported, its role in octogenarians has yet to be elucidated. This retrospective study was designed to compare the outcomes of open
Xiaoqiang Zhu, Zhengni Liu, Jianfeng Shen, Jiajie Liu, Rui Tang   +4 more
doaj  

HERNIA OF THE BLADDER

Annals of Surgery, 1922
n ...
openaire   +3 more sources

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp, Elizabeth A. VanSickle, Julianne Michael, Chad R. Schultz, Kelly Nguyen, Melissa Hoefer, Surender Rajasekaran, André S. Bachmann   +7 more
wiley   +1 more source