Results 111 to 120 of about 1,032 (159)
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The Socioeconomics of Heroin Dependency
New England Journal of Medicine, 1972Abstract The present production and sale of heroin is an enterprise with gross profits that rivals many industries. Ten kilograms of opium grown in Asia and sold at $25 per kilogram will produce 1 kg of uncut heroin worth $20,000 in the United States. The ultimate aggregate worth of the same kilogram of heroin may be as much as $400,000.
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The Effect Of Heroin Dependence On Resumption Of Heroin Self-Administration In Rats
Drug and Alcohol Dependence, 2014It has been proposed that relapse vulnerability in previously dependent individuals results from augmentation of drug-induced reinforcement due to repeated associations between the interoceptive properties of the drug and reduction of acute withdrawal distress.To test this hypothesis, male Sprague-Dawley rats self-administered 0.05 mg/kg/inf heroin on ...
Meenu Minhas, Francesco Leri
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JAMA: The Journal of the American Medical Association, 1974
To the Editor.— The problem of treating heroin addicts continues to go unresolved. The supporters and detractors of methadone maintenance programs produce more and more evidence to support their divergent views. The sobering fact remains that we are no nearer success in the treatment of heroin addiction than we were a decade ago.
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To the Editor.— The problem of treating heroin addicts continues to go unresolved. The supporters and detractors of methadone maintenance programs produce more and more evidence to support their divergent views. The sobering fact remains that we are no nearer success in the treatment of heroin addiction than we were a decade ago.
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Prescription of Heroin for the Management of Heroin Dependence
CNS Drugs, 2009The prescription of heroin (diamorphine) for the management of heroin dependence is a controversial treatment approach that was limited to Britain until the 1990s. Since then a number of countries have embarked upon clinical trials of this approach, and it is currently licensed and available in several European countries.
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Heroin reward is dependent on a dopaminergic substrate
Life Sciences, 1981Abstract The rewarding property of heroin was blocked by pretreatment with either naloxone or pimozide, suggesting that this opiate-receptor mediated effect is dependent on a dopaminergic substrate. The involvement of a dopaminergic mechanism in this effect supports the notion that opiates and other sources of reward activate a similar neural ...
Michael A. Bozarth, Roy A. Wise
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Outpatient Methadone Withdrawal for Heroin Dependence
The American Journal of Drug and Alcohol Abuse, 1980The outcome of outpatient methadone withdrawal reported in 20 published studies during the 1970s varied widely: none to 62% of the patients completed withdrawal, none to 35% became abstinent at termination of withdrawal, and none to 38% were abstinent at follow-up.
Moses Esquivel +2 more
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Pharmacologic Treatment of Heroin-Dependent Patients
Annals of Internal Medicine, 2000Patients with heroin dependence frequently present to internists and other physicians for heroin-related medical, psychiatric, and behavioral health problems and often seek help with reducing their heroin use. Thus, physicians should be familiar with the identification and diagnosis of heroin dependence in their patients and be able to initiate ...
David A. Fiellin, Patrick G. O'Connor
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Heroin dependence and HIV infection in Malaysia
Drug and Alcohol Dependence, 2006Malaysia is experiencing severe problems with heroin dependence and HIV infection. This, study evaluated drug use and other HIV risk behaviors and their association with HIV and other infectious diseases in heroin-dependent subjects enrolled in a clinical trial of drug abuse treatment in Muar, Malaysia.Baseline assessment of treatment-seeking subjects (
Marek C. Chawarski +2 more
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The current status of heroin prescription treatment for heroin dependence
Expert Opinion on Drug Safety, 2005Heroin prescription (HP) to treat severe heroin dependence has been available to few patients in the UK for several decades with limited, but generally favourable, evaluation. In the last decade, large trials have been reported from two countries, are presently underway in three other countries and under consideration in several other countries.
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Hopelessness in alcohol - and heroin-dependent women
Journal of Clinical Psychology, 1984Administered the Beck Hopelessness Scale to 20 alcoholic and 20 heroin-addicted women. A Weighted G analysis then was performed with the 20 dichotomous items of this scale to determine whether specific items differentiated between the two types of women.
Robert A. Steer +2 more
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