Results 111 to 120 of about 22,299 (230)

Prevalence of Active HCV Infection in Spain in 2022 Using Multiparameter Evidence Synthesis

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 4, April 2026.
ABSTRACT Hepatitis C virus (HCV) remains a major public health concern worldwide. Spain has implemented large‐scale direct‐acting antiviral (DAA) treatment programs, yet the prevalence of active HCV infection (aHCV) and its trends over time remain incompletely characterised.
Christos Thomadakis   +27 more
wiley   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao   +4 more
wiley   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 869-878, March 2026.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

Olanzapine Attenuates the Morphine‐Induced Conditioned Place Preference: The Involvement of the D2‐Like Dopamine Receptors

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
The results of this study demonstrated that olanzapine can inhibit morphine‐induced CPP behavior during the acquisition, expression, and extinction phases. These effects are likely mediated by the inhibition of dopamine receptors and a reduction in D2R protein expression in the HIP.
Farkhondeh Rzazzaghi‐ Firozjaei   +6 more
wiley   +1 more source

The Mediating Role of Emotion Dysregulation in the Association Between Impulsivity and Severity of Substance Dependence

open access: yesClinical Psychology &Psychotherapy, Volume 33, Issue 2, March/April 2026.
ABSTRACT Substance use disorders (SUDs) are among the leading causes of morbidity and mortality globally. Identification of aetiological factors related to the severity of substance use can offer targets for therapeutic interventions. Role of impulsivity and emotion dysregulation in SUDs is well established.
Giovanni Mansueto   +4 more
wiley   +1 more source

Phenomenological research in the field of Infant Mental Health and Early Childhood (IECMH) ‐A mapping review

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 47, Issue 2, March 2026.
Abstract Infant Mental Health and Early Childhood (IECMH) is a field of study of infants and the developing relationship and the optimal development between infants and their caregivers. Phenomenological research within the well‐being of infants and caregivers has core importance in the comprehension of the subjectivity of the infant and the attachment
Minna Sorsa, Bente Dahl, Idun Røseth
wiley   +1 more source

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