Results 231 to 240 of about 375,473 (301)

Early parent‐child interaction and home environments of children exposed prenatally to opioids: A comparison of biological mothers and out‐of‐home caregivers

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 46, Issue 3, Page 343-358, May 2025.
Abstract Children born to mothers with opioid use disorder (OUD) are at increased risk of maltreatment and out‐of‐home care (OOHC) placement. This study examines the parent‐child interaction quality and home environments of 92 New Zealand children with prenatal opioid exposure (OE) and 106 non‐opioid‐exposed (NE) children.
Samantha J. Lee   +2 more
wiley   +1 more source

Current drug use patterns and HIV and HCV prevalence among people who inject drugs in suburban areas of Malaysia

open access: yesJournal of the International AIDS Society, Volume 28, Issue 5, May 2025.
Abstract Introduction National surveillance data in Malaysia has observed a marked reduction in the number of new HIV cases among people who inject drugs (PWID) in the past decade. This study sought to estimate the current prevalence and associated risk factors of HIV and hepatitis C virus (HCV) among PWID in suburban areas of Klang Valley, Malaysia ...
Joselyn Pang   +5 more
wiley   +1 more source

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie   +10 more
wiley   +1 more source

Efficacy of cannabidiol alone or in combination with Δ‐9‐tetrahydrocannabinol for the management of substance use disorders: An umbrella review of the evidence

open access: yesAddiction, Volume 120, Issue 5, Page 813-834, May 2025.
Abstract Background and Aims Substance use disorders (SUD) lead to a high burden of disease, yet treatment options are limited. Cannabidiol (CBD) is being investigated as a potential therapeutic target due to its pharmacological properties and mode of action in the endocannabinoid system.
Bertrand Redonnet   +4 more
wiley   +1 more source

Is methamphetamine blood concentration in emergency department patients associated with the clinical picture?

open access: yesAddiction, Volume 120, Issue 5, Page 1007-1015, May 2025.
Abstract Aims This study aimed to describe clinical features and outcomes of patients presenting to the emergency department with analytically confirmed methamphetamine intoxication, to determine the blood concentration of methamphetamine and to test its association with clinical findings.
David McCutcheon   +7 more
wiley   +1 more source

Extended‐release pharmacotherapies for substance use disorders in incarcerated populations: A systematic review

open access: yesAddiction, Volume 120, Issue 5, Page 835-859, May 2025.
Abstract Background and aims Substance use (SU) is prevalent among individuals in the criminal justice system (CJS). However, there is often poor access to treatment. We aimed to assess the effectiveness of two medications, extended‐release naltrexone (XR‐NTX) and extended‐release buprenorphine (XR‐BUP) for the prison population.
Amelia Woods   +7 more
wiley   +1 more source

Case series: Symptom‐inhibited fentanyl induction (SIFI) onto treatment‐dose opioid agonist therapy in a community setting

open access: yesThe American Journal on Addictions, Volume 34, Issue 3, Page 355-360, May 2025.
Abstract Background and Objectives Existing opioid agonist therapy (OAT) guidelines are far from sufficient to address rising opioid tolerances and potency of the unregulated opioid market in North America. Inadequate starting doses of OAT are a universally recognized barrier for people who use fentanyl.
Pouya Azar   +11 more
wiley   +1 more source

Cannabis Legalization and its Effects on Organized Crime: Lessons and Research Recommendations from Canada

open access: yesSociological Inquiry, Volume 95, Issue 2, Page 394-414, May 2025.
In October 2018, Canada legalized and regulated its entire recreational cannabis supply chain via the Cannabis Act. One of the objectives of this new policy was to take revenue away from organized crime groups. Five years after the Cannabis Act went into effect, we address the following question: what do we know about the impacts of cannabis regulation
Martin Bouchard   +2 more
wiley   +1 more source

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