Results 231 to 240 of about 375,473 (301)
Abstract Children born to mothers with opioid use disorder (OUD) are at increased risk of maltreatment and out‐of‐home care (OOHC) placement. This study examines the parent‐child interaction quality and home environments of 92 New Zealand children with prenatal opioid exposure (OE) and 106 non‐opioid‐exposed (NE) children.
Samantha J. Lee+2 more
wiley +1 more source
Abstract Introduction National surveillance data in Malaysia has observed a marked reduction in the number of new HIV cases among people who inject drugs (PWID) in the past decade. This study sought to estimate the current prevalence and associated risk factors of HIV and hepatitis C virus (HCV) among PWID in suburban areas of Klang Valley, Malaysia ...
Joselyn Pang+5 more
wiley +1 more source
GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie+10 more
wiley +1 more source
Abstract Background and Aims Substance use disorders (SUD) lead to a high burden of disease, yet treatment options are limited. Cannabidiol (CBD) is being investigated as a potential therapeutic target due to its pharmacological properties and mode of action in the endocannabinoid system.
Bertrand Redonnet+4 more
wiley +1 more source
Sleep disturbance and its associations with severity of dependence, depression and quality of life among heroin-dependent patients: a cross-sectional descriptive study [PDF]
Vincent Chin‐Hung Chen+4 more
openalex +1 more source
'Loss of control' in alcoholism and drug addiction:A neuroscientific interpretation [PDF]
Lyvers, M.
core +1 more source
Abstract Aims This study aimed to describe clinical features and outcomes of patients presenting to the emergency department with analytically confirmed methamphetamine intoxication, to determine the blood concentration of methamphetamine and to test its association with clinical findings.
David McCutcheon+7 more
wiley +1 more source
Abstract Background and aims Substance use (SU) is prevalent among individuals in the criminal justice system (CJS). However, there is often poor access to treatment. We aimed to assess the effectiveness of two medications, extended‐release naltrexone (XR‐NTX) and extended‐release buprenorphine (XR‐BUP) for the prison population.
Amelia Woods+7 more
wiley +1 more source
Abstract Background and Objectives Existing opioid agonist therapy (OAT) guidelines are far from sufficient to address rising opioid tolerances and potency of the unregulated opioid market in North America. Inadequate starting doses of OAT are a universally recognized barrier for people who use fentanyl.
Pouya Azar+11 more
wiley +1 more source
In October 2018, Canada legalized and regulated its entire recreational cannabis supply chain via the Cannabis Act. One of the objectives of this new policy was to take revenue away from organized crime groups. Five years after the Cannabis Act went into effect, we address the following question: what do we know about the impacts of cannabis regulation
Martin Bouchard+2 more
wiley +1 more source