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Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Anders Helander, Fredrik Sparring
wiley +1 more source
Background: Heroin is currently contributing to the worst drug addiction epidemic in United States history; recent rates of use, dependence and death have also increased dramatically in parts of Europe.
Christina Marel+5 more
doaj
Understanding the factors driving the opioid epidemic using machine learning [PDF]
In recent years, the US has experienced an opioid epidemic with an unprecedented number of drugs overdose deaths. Research finds such overdose deaths are linked to neighborhood-level traits, thus providing opportunity to identify effective interventions.
arxiv
The SUMMIT trial: a field comparison of buprenorphine versus methadone maintenance treatment. [PDF]
This prospective patient-preference study examined the effectiveness in practice of methadone versus buprenorphine maintenance treatment and the beliefs of subjects regarding these drugs. A total of 361 opiate-dependent individuals (89% of those eligible,
Holland, R+5 more
core +1 more source
Abstract Objective Evaluating the efficacy of an opioid antagonist, naloxone (NLX), to reduce the severity of post‐ictal hypoxemia and immobility after focal to bilateral tonic–clonic seizures (FBTCS). Methods ENALEPSY is a double‐blind placebo (PCB)‐controlled trial conducted in patients with focal epilepsy undergoing long‐term video‐EEG monitoring ...
Sylvain Rheims+71 more
wiley +1 more source
Background Addiction is a relapsing chronic condition in which psychiatric phenomena play a crucial role. Psychopathological symptoms in patients with heroin addiction are generally considered to be part of the drug addict's personality, or else to be ...
Maremmani Icro+8 more
doaj +1 more source
Location inference on social media data for agile monitoring of public health crises: An application to opioid use and abuse during the Covid-19 pandemic [PDF]
The Covid-19 pandemic has intersected with the opioid epidemic to create a unique public health crisis, with the health and economic consequences of the virus and associated lockdowns compounding pre-existing social and economic stressors associated with rising opioid and heroin use and abuse. In order to better understand these interlocking crises, we
arxiv
Resting-state Abnormalities in Heroin-dependent Individuals [PDF]
Drug addiction is a major health problem worldwide. Recent neuroimaging studies have shed light into the underlying mechanisms of drug addiction as well as its consequences to the human brain. The most vulnerable, to heroin addiction, brain regions have been reported to be specific prefrontal, parietal, occipital, and temporal regions, as well as, some
Leda Kovatsi+3 more
openaire +3 more sources
Percolation on networks with weak and heterogeneous dependency [PDF]
In real networks, the dependency between nodes is ubiquitous; however, the dependency is not always complete and homogeneous. In this paper, we propose a percolation model with weak and heterogeneous dependency; i.e., dependency strengths could be different between different nodes. We find that the heterogeneous dependency strength will make the system
arxiv +1 more source
Modeling Policy and Agricultural Decisions in Afghanistan [PDF]
Afghanistan is responsible for the majority of the world's supply of poppy crops, which are often used to produce illegal narcotics like heroin. This paper presents an agent-based model that simulates policy scenarios to characterize how the production of poppy can be dampened and replaced with licit crops over time.
arxiv +1 more source