Results 51 to 60 of about 586,499 (386)
Pathogen burden and cortisol profiles over the day [PDF]
Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood.
Bergstrom, S +4 more
core +1 more source
Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease
Strong evidence has emerged recently for the concept that herpes simplex virus type 1 (HSV1) is a major risk for Alzheimer’s disease (AD). This concept proposes that latent HSV1 in brain of carriers of the type 4 allele of the apolipoprotein E gene (APOE-
R. Itzhaki
semanticscholar +1 more source
Immunization with nucleoside-modified mRNA encoding herpes glycoproteins C, D, and E protects against genital herpes. Hinting at a herpes vaccine Currently, a vaccine for genital herpes does not exist despite the prevalence of this sexually transmitted ...
Sita Awasthi +8 more
semanticscholar +1 more source
Actin in Herpesvirus Infection
Actin is important for a variety of cellular processes, including uptake of extracellular material and intracellular transport. Several emerging lines of evidence indicate that herpesviruses exploit actin and actin-associated myosin motors for viral ...
Joel D. Baines, Kari L. Roberts
doaj +1 more source
A complex network of processes inside the human immune system provides resistance against a wide range of pathologies. These defenses form an innate and adaptive immunity, in which certain immune components work together to counteract infections.
Andrea Ricci, Giovanni N. Roviello
doaj +1 more source
Herpes simplex virus-type1 (HSV-1) impairs DNA repair in cortical neurons [PDF]
Several findings suggest that Herpes simplex virus-1 (HSV-1) infection plays a role in the neurodegenerative processes that characterize Alzheimer's disease (AD), but the underlying mechanisms have yet to be fully elucidated.
Alessio Cardinale +12 more
core +2 more sources
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor +4 more
core +1 more source
Herpes gestationis, also known as pemphigoidgestationis (PG) is an extremely rare autoimmune bullous dermatosis of the gestation and postpartum period. The disease was originally named herpes gestationis on the basis of the morphological herpetiform feature of the blisters.
Ivelina Yordanova +4 more
openaire +2 more sources
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source

