Results 11 to 20 of about 3,748 (212)

First‐in‐human, randomized, double‐blind, placebo‐controlled, dose escalation trial of the anti‐herpes simplex virus monoclonal antibody HDIT101 in healthy volunteers

Clinical and Translational Science, Volume 15, Issue 10, Page 2366-2377, October 2022., 2022
Abstract HDIT101 is a first‐in‐class humanized monoclonal antibody recognizing a conserved epitope in glycoprotein B, a target present on the surface of herpes simplex virus 1 (HSV‐1) and HSV‐2 particles as well as on virus‐infected cells. This was a first‐in‐human, single‐center, double‐blind, placebo‐controlled trial in 24 healthy volunteers ...
Antje Blank, Nicolas Hohmann, Marlen Dettmer, Anette Manka‐Stuhlik, Gerd Mikus, Felicitas Stoll, Marlies Stützle‐Schnetz, Daniel Thomas, Evelyn Exner, Beate Schmitt‐Bormann, Torsten Schaller, Rico Laage, Oliver Schönborn‐Kellenberger, Michaela Arndt, Walter E. Haefeli, Jürgen Krauss   +15 more
wiley   +1 more source

Infektionen mit Herpes‐simplex‐ und Varizella‐zoster‐Virus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 10, Page 1327-1353, October 2022., 2022
Zusammenfassung Humane Herpesviren gehören zu den DNA‐Viren und zählen zu den häufigsten Erregern viraler Infektionen beim Menschen. Nach der Primärinfektion mit einem dieser Viren kommt es typischerweise zur Latenz mit dem Potenzial späterer Reaktivierungen, die häufiger symptomatisch sind und zum Arztbesuch führen als die Primärinfektion.
Larissa Wilms, Katharina Weßollek, Theresa Barbara Peeters, Amir Sadegh Yazdi   +3 more
wiley   +1 more source

Hypopigmented penile fixed drug eruption

Clinical Case Reports, Volume 10, Issue 9, September 2022., 2022
Residual hypopigmentation can occur in FDE. Epithelial hyperplasia is a histopathologic feature of chronic lesions. Refractory period can influence response to oral DPT; thus, patient may need to be observed longer than the recommended 7 days. Chronic recurring FDE of the glans penis and meatal area can cause meatal stenosis.
Perpetua U. Ibekwe, Hafees O. Ajibola, Zainabb Babba, Grace Otokpa, Raphael Solomon, Bob A. Ukonu   +5 more
wiley   +1 more source

Sexually Transmitted Dermatophyte Infections-A Scoping Review. [PDF]

Mycoses
ABSTRACT Sexually transmitted dermatophyte infections are an emerging public health concern, with increasing incidence reported across multiple countries. These infections are mainly spread through direct skin‐to‐skin contact during sexual activity and are more commonly found in individuals with high‐risk sexual practices.
Gupta AK, Liddy A, Megal L, Kaplan B, Shemer A, Saunte DML, Wang T.   +6 more
europepmc   +2 more sources

Comprehensive clinical and virological characterization of three cases of fulminant liver failure owing to HSV1 primary infection

Liver International, Volume 42, Issue 5, Page 1005-1011, May 2022., 2022
Abstract Herpes simplex virus 1 (HSV‐1) is a frequently unrecognized, yet deadly cause of acute liver failure (ALF). We, therefore, analysed three cases of fatal HSV‐1‐induced ALF. All patients shared clinical (extremely elevated transaminases, LDH and AST/LDH ratio < 1) and virological characteristics (ratio of viral load in plasma versus throat swabs:
Stephan Spahn, Reimer Riessen, Christoph P. Berg, Nisar P. Malek, Marzena H. Emrich, Kristina Lohrengel, Tina Ganzenmueller, Thomas Iftner, Gerald Kleymann, Klaus Hamprecht   +9 more
wiley   +1 more source

Kenntnisse bayerischer Schüler zu sexuell übertragbaren Infektionen: eine Querschnittsstudie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 2, Page 169-176, February 2022., 2022
Zusammenfassung Hintergrund und Ziele Trotz zahlreicher Informationsquellen und Kampagnen zu sexuell übertragbaren Infektionen (STI) haben diese Krankheiten in Deutschland in den letzten Jahren zugenommen. Ziel war es, das Bewusstsein und den Wissensstand junger Schüler in Bayern zu sexuell übertragbaren Krankheiten (STI) mit Schwerpunkt auf humane ...
Marcel Rummel, Benjamin M. Clanner‐Engelshofen, Tobias Nellessen, Stefan Zippel, Barbara Schuster, Lars E. French, Markus Reinholz   +6 more
wiley   +1 more source

Efficacy and Safety of Clinacanthus nutans Lindau Cream vs. Podophyllin for the Treatment of Adults with Condyloma Acuminata

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Human papillomavirus (HPV) infection causes condyloma acuminata (CA). Podophyllin is the standard treatment. Clinacanthus nutans Lindau (C. nutans), a medicinal plant, has potent anti‐inflammatory and antiviral effects. C. nutans cream is widely used in Thailand to treat the herpes simplex virus. We proposed that C.
Sukhum Jiamton, Pattriya Chanyachailert, Yanisorn Nanchaipruek, Nuttagarn Jantanapornchai, Poramin Patthamalai, Pichaya Limphoka, Ya-Nin Nokdhes, Jiraporn Jantaravinid, Maan B. Rokaya   +8 more
wiley   +1 more source

Emphysematous Pyelonephritis Caused by E.Coli and Candida Albicans with Oral Candidiasis and Herpes Genitalis: A Dreaded Infection [PDF]

Journal of Clinical and Diagnostic Research, 2018
Emphysematous Pyelonephritis (EPN) is a rare, potentially fatal necrotising pyelonephritis, with rising trend in diabetic patients (95%). E.coli is the most common uropathogen whereas Candida albicans is extremely rare.
Shyam Lal, Ankit Kaura, Pradhuman Yadav, Isha   +3 more
doaj   +1 more source

Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression

Case Reports in Obstetrics and Gynecology, Volume 2022, Issue 1, 2022., 2022
Background. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV‐2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation.
Daniel York, Pavan Patel, Smera Saikumar, Seung-Yup Ku   +3 more
wiley   +1 more source

Vegetative chronic genital herpes with satisfactory response to imiquimod [PDF]

Anais Brasileiros de Dermatologia, 2019
Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus.
Stella Meireles Siqueira, Bruna Barroso Gonçalves, Julia Bozetti Loss, Rogerio Ribeiro Estrella   +3 more
doaj   +2 more sources