Results 91 to 100 of about 13,090 (254)

Auto‐inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter

Immunology &Cell Biology, EarlyView.
The NR4A1 promoter is a compact auto‐inducible promoter to drive CAR expression in T cells. Compared with EF1α, or existing synthetic antigen‐inducible promoters, NR4A1 is more compact and ensures that resting CAR T cells express reduced baseline CAR. NR4A1 allows rapid induction upon antigen encounter with reduced T‐cell exhaustion.
Samuel WJ Smith‐Bell, Joshua C Halpin, Phillip K Darcy, Thiloma Liyanage, Lachlan J Dobson, Alexander D McLellan   +5 more
wiley   +1 more source

Infección bucal por el virus herpes simple tipo 1

Correo Científico Médico, 2012
Se describieron las principales características de la infección por el virus herpes simple tipo 1, sobre todo a nivel de la boca, se enfatizó en la replicación viral, la patogénesis, las manifestaciones clínicas, los mecanismos inmunitarios, las vías de ...
Sarah Negreira León, Yesenia Rodríguez Gago, Maria Julia Rosales Concepción   +2 more
doaj  

Apresentação atípica da ceratite herpética em lactente [PDF]

Revista Brasileira de Oftalmologia
RESUMO Este relato de caso descreve a apresentação clínica e o manejo de um lactente de 38 dias de vida, encaminhado ao Serviço de Oftalmologia para avaliação de hiperemia conjuntival, opacidade corneana e edema palpebral no olho esquerdo.
Bruno Frujuelli de Melo, Mathias Andre Kunde, Renato Sztern Queiroz, Guilherme Thomé de Carvalho, Annamaria Ciminelli Barbosa, Mario Martins dos Santos Motta   +5 more
doaj   +1 more source

Herpes simples : revisão da literatura

, 2020
Herpes simplex is a very important cause of infection in humans. The aim of this review was to describe its clinical features, drugs indicated for its treatments and its prevention. The prevalence of infection is very high, specially in HSV, type 1. Usually, HSV infection is mild and self-limitaded, but in imunodepressed patients, young children with a
Azambuja, Tais Weber Furlanetto de, Bercini, Francesca, Furlanetto, Tania Weber   +2 more
openaire   +1 more source

Self-reported genital warts among sexually-active university students: A cross-sectional study [PDF]

, 2018
Background: Genital warts are one of the most common forms of sexually-transmitted disease, but their epidemiology has yet to be thoroughly elucidated. The present study was designed to shed light on the prevalence of clinically-confirmed, self-reported ...
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Cocchio, Silvia, Majori, Silvia   +5 more
core   +3 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Dermatoses Específicas da Gravidez [PDF]

, 2013
During pregnancy immunological, metabolic, hormonal and vascular changes occur, and can cause specific skin diseases. The specific dermatoses of pregnancy have undergone numerous changes in nomenclature and classification, partly due to advances in the ...
Coutinho, I, Gameiro, R, Gonçalo, Margarida, Teixieira, V, Vieira, R   +4 more
core  

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Paralisia facial bilateral Bilateral facial paralysis: a case report

Arquivos de Neuro-Psiquiatria, 1976
É apresentado um caso de diplegia facial surgida após meningite meningocócica e infecção por herpes simples. Depois de discutir as diversas condições que o fenômeno pode apresentar-se, o autor inclina-se por uma etiologia herpética.A case of bilateral ...
J. Fortes-Rego
doaj  

Factores para herpes simple: Revisión de literatura

, 2022
Herpes simplex virus, after the first infection, can remain dormant in the lymph nodes and reactivate at any time due to certain factors and/or stimuli causing effects in the patient. The purpose of this literature review is to update scientific information on the factors that predispose to the reactivation of herpes simplex virus.
Begazo, Lisette, Morante, Alysson, Espinoza Montes, Carlos   +2 more
openaire   +1 more source