Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies
Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, Volume 13, Issue 35, 24 June 2026.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Aggregate, Volume 7, Issue 6, June 2026.Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
A Mechanistic Model of rAAV Production in Synthetic Cell Lines
Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1684-1694, June 2026.ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan +5 more
wiley +1 more source
[High seroprevalence of syphilis and genital herpes in migrants in transit in Chiapas, MexicoAlta soroprevalência de sífilis e herpes genital em migrantes em trânsito por Chiapas, México]. [PDF]
Rev Panam Salud Publica, 2023 Sánchez-Alemán MA +6 more
europepmc +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Ramsay Hunt syndrome, caused by varicella‐zoster virus reactivation, presents with facial paralysis, otalgia, and auricular vesicles. A Tanzanian woman with Grade VI facial palsy was treated with acyclovir and prednisolone, recovering to Grade II within 2 weeks.
Jacob Henry Kitundu +4 more
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‘BJUI Clinical Dilemma’: Recurrent high‐grade non‐muscle‐invasive bladder cancer in 2026
BJU International, Volume 138, Issue 1, Page 14-21, July 2026.
Vignesh T. Packiam +10 more
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Fibromyalgia in the Setting of Prior Epstein–Barr Virus Infection: A Case Report
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Accurate diagnosis of fibromyalgia requires careful consideration of overlapping conditions. This case underscores the role of Epstein–Barr virus (EBV) serology in patients with persistent fatigue and pain, while illustrating the challenges of diagnosing fibromyalgia amid concurrent health problems.
Saachi Bhattessa, Tirth Dave, Priti Modi
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Neonatal Herpes Simplex Virus Keratitis: Bitter Lessons from a Case Report
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Neonatal herpes simplex virus (HSV) infection is an uncommon but potentially devastating condition. Ocular involvement, particularly herpetic keratitis, can cause significant morbidity if not promptly recognized and treated. We present a case of isolated HSV‐1 keratitis in a 25‐day‐old neonate successfully managed with intravenous acyclovir ...
Mohammad Saeid Sasan, Amin Saeidinia
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