Results 91 to 100 of about 262,851 (250)

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

Herpes simples : revisão da literatura

, 2020
Herpes simplex is a very important cause of infection in humans. The aim of this review was to describe its clinical features, drugs indicated for its treatments and its prevention. The prevalence of infection is very high, specially in HSV, type 1. Usually, HSV infection is mild and self-limitaded, but in imunodepressed patients, young children with a
Azambuja, Tais Weber Furlanetto de, Bercini, Francesca, Furlanetto, Tania Weber   +2 more
openaire   +1 more source

Special papers Herpes progenitalis – prevention of herpes simplex virus infections

, 2015
Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucosal erosions and ulcerations in the genital area.
Ewelina Biało-Wójcicka, Sławomir Majewski, Katarzyna Łoza   +2 more
core   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Alterações de comportamento na encefalite herpética: um caso polimórfico e de difícil manejo

Jornal Brasileiro de Psiquiatria, 2015
RESUMO A encefalite herpética é uma doença de alta mortalidade que deve ser diagnosticada e tratada rapidamente. Cefaleia, febre e alteração de comportamento compõem a tríade clássica.
Gustavo Carvalho de Oliveira, Moema de Carvalho Madeira, Margareth Diniz Celmer   +2 more
doaj   +1 more source

Herpes simple zosteriforme en lactante

Medimay, 2010
Se presentó el caso clínico de un lactante de 9 meses de nacido, con herpes simple zosteriforme recidivante, que siguió el trayecto del nervio facial, y secundariamente se infectó por bacterias. El paciente tiene antecedentes patológicos personales de atopia y familiares de herpes simple labial, ambas de importancia para la enfermedad.
Elisa Ruiz Hernández, Alicia Bravo Hernández   +1 more
openaire   +3 more sources

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

International Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo, Isotta Giunipero di Corteranzo, Pietro Quaglino, Simone Ribero, Francois Rosset   +4 more
wiley   +1 more source

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Herpes genital

DST, 1989
Os vírus da família Herpesviridae caracterizam-se pela habilidade de se tornarem latentes e produzirem infecções recorrentes. Os vírus herpes simples (HSV) com dois sorotipos distintos, HSV-1 e HSV-2, têm como reservatório natural os seres humanos. [...]
Ledy do Horto dos Santos Oliveira
doaj