Results 291 to 300 of about 413,028 (398)

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

What is chronic urinary tract infection? A systematic review

BJU International, Volume 136, Issue 1, Page 12-18, July 2025.
Objective To define ‘chronic’ urinary tract infection (UTI) by reviewing current published research that employs this term. Methods We systematically searched Medline and Embase for studies covering all aspects of human UTI. For comparison, current urological and infectious disease guidelines were also reviewed.
Janni Søvsø Hjelmager, Karin Andersen, Thomas Emil Andersen, Kristian Stærk   +3 more
wiley   +1 more source

Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics Analysis

Brain and Behavior, Volume 15, Issue 6, June 2025.
MR analysis evaluates the bidirectional causal relationships between 91 circulating inflammatory proteins and NDDs, contingent upon three critical hypotheses: (1) Correlation hypothesis: SNPs must be strongly correlated with the exposure; (2) Independence hypothesis: SNPs should not be associated with any potential confounding factors; (3) Exclusivity ...
Ziwei Gong, Rong Cao, Hong Zhu
wiley   +1 more source

Unveiling the clinical spectrum of herpes simplex virus CNS infections in adults: a systematic review. [PDF]

Syst Rev
Grzonka P, Mosimann T, Berger S, Amacher SA, Baumann SM, Gebhard CE, De Marchis GM, Dittrich TD, Sutter R.   +8 more
europepmc   +1 more source

Higher risk behaviours and STD rates in Tanzania compared to Uganda - contribution to different outcomes of STD treatment trials? [abstract] [PDF]

, 2001
Grosskurth, H, Habbema, JDF, Hayes, RJ, Kamali, A, Korenromp, EL, Orroth, KK, Serwadda, D, Sewankambo, NK, White, RG, Whitworth, JAG   +9 more
core  

Fibrotic Fortresses and Therapeutic Frontiers: Pancreatic Stellate Cells and the Extracellular Matrix in Pancreatic Cancer

Cancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by a unique tumor microenvironment (TME) that plays pivotal roles in cancer progression, angiogenesis, metastasis, and drug resistance. This complex and dynamic ecosystem comprises cancer cells, stromal cells, and extracellular matrix (ECM) components, which interact ...
Sila Sigirli, Didem Karakas
wiley   +1 more source

Assessment of IL28 (rs12980275) and (rs8099917) Frequency in Recurrent Ocular Herpes Simplex Virus (HSV) Infection. [PDF]

Life (Basel)
Savic B, Savic B, Kalezic T, Dacic-Krnjaja B, Milosevic V, Petrovic Pajic S, Maric V, Petrovic T, Stanojlovic S.   +8 more
europepmc   +1 more source

Effective Treatment of Livedoid Vasculopathy With Oral Tofacitinib

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT We present a woman with severe refractory livedoid vasculopathy who was successfully treated with tofacitinib (5 mg twice a day). The ulcers gradually healed over a period of 2–3 months without experiencing any adverse events over a 1‐year follow‐up period.
Parvin Mansouri, Nikoo Mozafari
wiley   +1 more source

A novel approach utilizing spirocyclic thiopyrimidinone compounds against herpes simplex virus with underlying antiviral mechanisms of action. [PDF]

Virol J
Manie EA, Elzayat EM, Ragab SS, Sweed AM, Ibrahim H, Nasser S, Allayeh AK.   +6 more
europepmc   +1 more source