Results 211 to 220 of about 1,214,794 (308)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Herpes Simplex Virus Esophagitis in an Immunocompetent Patient: Navigating Diagnostic Challenges and Achieving Effective Treatment. [PDF]

Cureus
Mwengela D, Ather N, Kunesh J.
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Development of a HiFi-LAMP assay for the detection of herpes simplex virus type 1. [PDF]

Sci Rep
Wang Z, Wan Z, Zhao Y, Wang Z, Song S, Song ZG, Li YY, Zhang C.   +7 more
europepmc   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Herpes Simplex Virus 1 Encephalitis in First Trimester of Pregnancy: A Case Report. [PDF]

Case Rep Obstet Gynecol
Furlan M, Lučovnik M, Kmet NG.
europepmc   +1 more source

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

Herpes Simplex Virus 1 in Trigeminal Ganglia of Trafficked Neotropical Primates, Peru, 2024. [PDF]

Emerg Infect Dis
Vilchez-Delgado F, Zhou L, O'Connor S, Colan R, Escobar-Mendoza L, Mendoza AP, Ghersi BM, Andrade R, Talledo-Albújar M, Rosenbaum MH.   +9 more
europepmc   +1 more source

SUMOylation and ubiquitination reciprocally regulate SMCHD1 antiviral activity against herpes simplex virus 1. [PDF]

PLoS Pathog
Tian X, Wang X, Wang S, Zhong Y, Xia Y, Chen Y, He L, Pan D, Lan K, Zhang J.   +9 more
europepmc   +1 more source

Atypical genital-predominant mpox mimicking chancroid and herpes simplex virus infection: a case report and literature synthesis. [PDF]

BMC Infect Dis
Oshodin AE, Unuane AE, Saka SA, Njoku AI.   +3 more
europepmc   +1 more source