Results 91 to 100 of about 108,460,457 (303)

Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials.

open access: yes, 2010
Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcer disease and is a cofactor for HIV-1 acquisition and transmission. We analyzed specimens from three separate phase III trials of acyclovir (ACV) for prevention of HIV-1 ...
Kathy Baisley   +23 more
core   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang   +3 more
wiley   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell   +6 more
wiley   +1 more source

Characterization of the murine cytomegalovirus genes encoding the major DNA binding protein and the ICP18.5 homolog [PDF]

open access: yes, 1992
In several herpesviruses the genes for the major DNA binding protein (MDBP), a putative assembly protein, the glycoprotein B (gB), and the viral DNA polymerase (pol) coliocate.
Koszinowski, Ulrich H.   +3 more
core   +2 more sources

Prevalence of anti-herpes simplex virus type 1 among dental students of Birjand University of Medical Sciences, Iran, 2017-2018: Short Communication

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2021
Herpes simplex virus is considered one of the most common human infections in most parts of the world, among which, herpes simplex virus 1 (HSV-1) is one of the most important human pathogenic viruses that cause numerous skin and oral lesions ...
Parvin Parvaie   +4 more
doaj  

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

open access: yesJPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder   +3 more
wiley   +1 more source

Effect of Blended Learning Program on Awareness of Parents’ Caring for Children with Herpes Simplex [PDF]

open access: yesEgyptian Journal of Health Care
Background: Infection with the Herpes Simplex Viruses (HSV) type 1 and 2 is fairly frequent.  While HSV-1 infections have traditionally been linked with oral lesions and HSV-2 infections with genital illness, both virus serotypes can infect either region.
Fatma Abdellah Mohamed   +2 more
doaj   +1 more source

Herpes simplex virus 1 rhombencephalitis in a patient with chromosomally integrated human herpesvirus-6A

open access: yesIDCases, 2020
Central nervous system infection caused by Herpes simplex virus 1 remains a significant cause of morbidity and mortality in transplant patients. Additionally, the clinical implications of the recently discovered Human herpesvirus 6A are still under ...
Raquel Silva   +3 more
doaj   +1 more source

Ultrasound findings associated with neonatal acute liver failure secondary to gestational alloimmune liver disease: A case series

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Gestational alloimmune liver disease is the leading cause of neonatal acute liver failure, hypothesized to emerge from maternal exposure to an antigen that is expressed on fetal hepatocytes, resulting in maternal‐fetal alloimmune attack and activation of the complement cascade.
Naseem Ravanbakhsh   +6 more
wiley   +1 more source

Antiviral Activity of Crataegus azarolus Extract Against Herpes Simplex Virus Type 1

open access: yesBiology, Medicine & Natural Product Chemistry
Background: due to the spread of infections caused by the herpes simplex virus and the occurrence of antiviral resistance, many studies are conducted to obtain alternative treatments with better performance and fewer side effects.
Zhang Ming, Chen Yu, Liu Fang
doaj   +1 more source

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