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Herpes simplex encephalitis: an autopsy case with isolation of type 1 herpes simplex virus

Acta Neuropathologica, 1977
An adult case of herpes simplex encephalitis was studied after autopsy. Postmortem examination revealed necrotizing encephalitis associated with Cowdry type A intranuclear inclusion bodies in glial cells. Herper simplex virus type 1 was isolated from the removed brain.
S, Miyake   +5 more
openaire   +2 more sources

Herpes simplex virus type 1 and Alzheimer’s disease

Neurobiology of Aging, 1999
Until recently, the only risk factors implicated in noninherited cases of Alzheimer's disease were increasing age, Down's syndrome, and probably, head injury. Having found that herpes simplex type 1 virus (HSV1) is present in the brain of many elderly people, we discovered that it is a risk factor for Alzheimer's disease when in the central nervous ...
Dobson, CB; id_orcid 0000-0002-6483-4608   +1 more
openaire   +3 more sources

Herpes simplex virus-1–associated congenital cataract

American Journal of Ophthalmology, 2004
To report association of herpes simplex virus-type 1 (HSV-1) in four cases of congenital cataract.Prospective interventional case series.Four infants younger than 12 months, presenting with unilateral or bilateral congenital cataract, were included. The cases were clinically evaluated by the pediatric ophthalmologist.
Raghu, Hari   +5 more
openaire   +3 more sources

Herpes simplex virus type 1 replication and recombination

Biochimie, 1995
Herpesviruses are a very interesting model for studying DNA replication in eukaryotic systems since they encode most of the proteins required for this process. These include a protein that specifically binds to the virus origin of DNA synthesis, a single-stranded DNA binding protein, an heterotrimeric helicase-primase and an heterodimeric DNA ...
D, Bataille, A L, Epstein
openaire   +2 more sources

Congenital Infection with Herpes Simplex Virus Type 1

Pediatric Dermatology, 1987
Abstract: We treated a newborn who had congenital herpes simplex virus (HSV) type 1 infection in which extensive skin lesions occurred with no evidence of involvement of other ograns. The correct diagnosis was not made until the fifth day of life, but after effective treatment with intravenous acyclovir this child has remained in perfect health.
M T, Glover, D J, Atherton
openaire   +2 more sources

Shedding of herpes simplex virus Type 1 into saliva

Journal of Oral Pathology & Medicine, 1988
The shedding of herpes simplex virus Type 1 (HSV‐1) into saliva was studied in 110 healthy individuals, 55 patients who were undergoing oral surgery, and 21 immunocompromised patients in an asymptomatic Japanese population. Specimens were collected regularly for up to 2 months from each individual. Virus was recovered on at least one occasion from 4.5%
T, Kameyama   +4 more
openaire   +2 more sources

The transcriptome of herpes simplex virus 1

2016
Herpes simplex virus 1 (HSV-1) is an intensively studied human pathogen for a number of years, however many of its biological properties remain unknown. Although, several HSV-1 strains have been completely sequenced, and partial transcriptomes of the virus have been assigned, the exact transcriptional activity of the virus is yet to be elucidated ...
Zubković, Andreja   +8 more
openaire   +2 more sources

Viral MicroRNAs in Herpes Simplex Virus 1 Pathobiology

Current Pharmaceutical Design
Abstract: Simplexvirus humanalpha1 (Herpes simplex virus type 1 [HSV-1]) infects millions of people globally, manifesting as vesiculo-ulcerative lesions of the oral or genital mucosa. After primary infection, the virus establishes latency in the peripheral neurons and reactivates sporadically in response to various environmental and genetic factors. A
Raza Ali Naqvi   +6 more
openaire   +2 more sources

Herpes simplex virus type 1 meningitis

The Pediatric Infectious Disease Journal, 1996
M H, Rathore, K, Mercurio, D, Halstead
openaire   +2 more sources

The heterogenous regions in herpes simplex virus 1 DNA.

Microbiologica, 1983
Restriction endonuclease analyses of herpes simplex virus (HSV-1) DNAs revealed variability in the electrophoretic migration of specific Bam HI and Kpn I fragments. The variable regions of the genome map at the ends and near the ends of both L and S components, near the L-S junction region and in middle of the S component.
TOGNON, Mauro   +3 more
openaire   +2 more sources

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