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Current Drugs to Treat Infections with Herpes Simplex Viruses-1 and -2

open access: yesViruses, 2021
Herpes simplex viruses-1 and -2 (HSV-1 and -2) are two of the three human alphaherpesviruses that cause infections worldwide. Since both viruses can be acquired in the absence of visible signs and symptoms, yet still result in lifelong infection, it is ...
Lauren A. Sadowski   +3 more
doaj   +1 more source

The World of Antiherpetic Vaccines and Drugs, 2022

open access: yesViruses, 2022
The world of antiherpetics has grown by leaps and bounds since the discovery of what would become the first antiherpetic drug in 1964 [...]
Barry J. Margulies
doaj   +1 more source

Pioneer factors in viral infection

open access: yesFrontiers in Immunology, 2023
Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their importance during embryonic development, for instance, in inducing
Eva Neugebauer   +9 more
doaj   +1 more source

Towards a comprehensive view of the herpes B virus

open access: yesFrontiers in Immunology, 2023
Herpes B virus is a biosafety level 4 pathogen and widespread in its natural host species, macaques. Although most infected monkeys show asymptomatic or mild symptoms, human infections with this virus can cause serious neurological symptoms or fatal ...
Jiangling Lu   +10 more
doaj   +1 more source

Seroprevalence of Herpes Simplex Virus type-1antibodies (IgM,IgG) in smokers in Kirkuk city-Iraq

open access: yesTikrit Journal of Pure Science, 2023
Herpes Simplex Virus type-1 (HSV-1) is classified in the α-herpes virus group of the Herpesviridae and HSV-1 infections are very common in the human population. The objective of this study is to determine the prevalence of anti-herpes simplex virus type-
Lezan Medhat Mohammed Zangana
doaj   +1 more source

Herpes B virus: History, zoonotic potential, and public health implications

open access: yesBiosafety and Health, 2022
Recently, death from herpes B virus (Cercopithecine Herpesvirus 1) infection was reported in China, reminding us to be alert to the risk of transmission and infection with herpes B virus.
Geng Hu   +4 more
doaj   +1 more source

Chronic Pediatric Immune Thrombocytopenia Is Not Associated With Herpes Virus Infection Status

open access: yesFrontiers in Pediatrics, 2021
Background: Immune thrombocytopenia (ITP) is characterized by non-chronic (transient, <12 months) and chronic (≥12 months) decline in the number of platelets.
Tao Li   +11 more
doaj   +1 more source

Incursions by severe acute respiratory syndrome coronavirus-2 on the host anti-viral immunity during mild, moderate, and severe coronavirus disease 2019 disease

open access: yesExploration of Immunology, 2022
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the human host can lead to various clinical manifestations, from symptomless carriers to mild to moderate to severe/critical illness.
Nitin Saksena   +3 more
doaj   +1 more source

RNA interference inhibits herpes simplex virus type 1 isolated from saliva samples and mucocutaneous lesions

open access: yesBrazilian Journal of Infectious Diseases, 2014
The aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex virus type-1 replication in vitro. For herpes simplex virus type-1 gene silencing, three different small interfering RNAs (siRNAs) targeting the herpes simplex ...
Amanda Perse da Silva   +2 more
doaj   +1 more source

The impact of chronic herpes virus infection on the bone system in children

open access: yesДетские инфекции (Москва), 2023
Herpes virus infections currently are urgent problem in infectology, pediatrics and therapy. The feature of these diseases is the possibility of direct and indirect effects of the virus on various organs and systems: immune, nervous, endocrine, bone, in ...
M. A. Telesh   +2 more
doaj   +1 more source

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