Results 171 to 180 of about 1,234,222 (260)

Trained Immunity in Childhood Vaccination

Acta Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Caprine herpes virus-1 reduces cell viability and enhances chemosensitivity in breast cancer cells. [PDF]

Front Oncol
Iannuzzi CA, Pagano F, Tomeo M, Sfera A, Calabrese A, Alfano L, Carmerlingo R, Cocco S, Damiano S, Montagnaro S, Ciarcia R, Giordano A, De Laurentiis M, von Arx C, Forte IM.   +14 more
europepmc   +1 more source

T cells and the regulation of herpes simplex virus latency and reactivation [PDF]

, 2000
Anthony A. Nash, Nash, A A
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

MicroRNA-138 regulation promotes the efficacy of oncolytic herpes virus G47Δ for malignant brain tumor therapy. [PDF]

Mol Ther Oncol
Kanayama S, Haraguchi T, Iba H, Tanaka M, Todo T.   +4 more
europepmc   +1 more source

Human Herpes Virus 6-Associated Meningitis in an Immunocompetent Adult With a History of Plaque Psoriasis: A Case Report. [PDF]

Cureus, 2023
Makhoul Wahbah G, Asogwa N, Ling JC, Agarwal A, Rimsky E, Glaser A.   +5 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

The crystal structure of the herpes virus ICP8 protein in complex with single-stranded DNA reveals the molecular determinants of nucleotide recognition. [PDF]

J Biol Chem
Erlandsen H, Krucinska J, Wilderman PR, Makkay AM, Szczepaniak R, Wright LR, Weller SK, Wright DL.   +7 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Association between B and T lymphocyte attenuator/herpes virus entry mediator immunoregulatory axis and outcome prediction in a mixed critically ill population. [PDF]

Sci Rep
Kokkoris S, Theodorou E, Lotsios NS, Keskinidou C, Vrettou CS, Poupouzas G, Issaris V, Premetis I, Kotanidou A, Dimopoulou I, Vassiliou AG.   +10 more
europepmc   +1 more source