Development of Novel Immunoassays for Varicella Zoster Virus (VZV) Vaccine and Preliminary Study on Functional Domain of ORF7 protein [PDF]
水痘-带状疱疹病毒(Varicella-ZosterVirus,VZV)是水痘和带状疱疹的病原体。VZV具有高度传染性,初次感染可引发水痘,并可潜伏于患者背根神经节,在年老或免疫力低下时可能激活导致带状疱疹,具有严重的危害性。接种疫苗是预防VZV感染的有效方式,但目前使用的VZV减毒活疫苗株v-Oka仍具有感染和潜伏人神经系统的能力,安全隐患不容忽视,因此,亟需研制更为安全有效的新型疫苗。高效、精确的免疫分析技术体系是研制新型疫苗的重要基础。VZV是一种基因组约125Kb,拥有70个ORF ...
刘剑
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Effectiveness of the Recombinant Zoster Vaccine for Herpes Zoster Ophthalmicus in the United States.
Angela Lu +4 more
semanticscholar +1 more source
Background: Currently, the recombinant subunit vaccine and live attenuated vaccine in the prevention of herpes zoster are approved for marketing in China.
Jiaqi Wang +5 more
semanticscholar +1 more source
Preclinical immunogenicity of an adenovirus-vectored vaccine for herpes zoster [PDF]
Marta Ulaszewska +3 more
openalex +1 more source
EE202 Estimating the Public Health Benefits of Preventing Herpes Zoster and Postherpetic Neuralgia in Greece by Zoster Vaccines: A Modelling Study [PDF]
N Kotsopoulos +8 more
openalex +1 more source
A natural experiment on the effect of herpes zoster vaccination on dementia
Neurotropic herpesviruses may be implicated in the development of dementia1, 2, 3, 4–5. Moreover, vaccines may have important off-target immunological effects6, 7, 8–9.
Markus Eyting +5 more
semanticscholar +1 more source
Periorbital cellulitis with Zoster encephalitis: a case report
Herpes Zoster, which commonly affects individuals over 60 years of age, can lead to encephalitis, particularly in elderly or immunocompromised individuals. This case highlights the development of zoster encephalitis following Herpes Zoster ophthalmicus.
Mustafa Usanmaz +4 more
doaj +1 more source
A Dose-Response Study of a Live Attenuated Varicella-Zoster Virus (Oka Strain) Vaccine Administered to Adults 55 Years of Age and Older [PDF]
Decreased cell-mediated immune (CMI) response to varicella-zoster virus (VZV) is correlated with an increased risk of reactivation of latent virus from dorsal root sites, leading to herpes zoster.
Bailleux, Fabrice +5 more
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