Development of Genome Editing Approaches against Herpes Simplex Virus Infections
Viruses, 2021 Herpes simplex virus 1 (HSV-1) is a herpesvirus that may cause cold sores or keratitis in healthy or immunocompetent individuals, but can lead to severe and potentially life-threatening complications in immune-immature individuals, such as neonates or ...
Isadora Zhang, Zoe Hsiao, Fenyong Liu
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Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
, 2012 Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B. +2 more
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Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]
, 2011 Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M +60 more
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Human Exposure to Herpesvirus B–Seropositive Macaques, Bali, Indonesia
Emerging Infectious Diseases, 2002 Herpesvirus B (Cercopithecine herpesvirus 1) has been implicated as the cause of approximately 40 cases of meningoencephalitis affecting persons in direct or indirect contact with laboratory macaques. However, the threat of herpesvirus B in nonlaboratory
Gregory A. Engel +6 more
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Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
, 2011 Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
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Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1 [PDF]
, 2008 The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs.
Stewart, James P. +11 more
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The core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo [PDF]
, 2003 peer reviewedThe Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the
Markine-Goriaynoff, N +17 more
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The virus-immune hypothesis for cardiac dilatation [PDF]
Терапевтический архив, 2017 The paper gives an update on the pathogenetic role of viral infection and immune mechanisms in the development of cardiac dilatation at the cellular, ultrastructural, and molecular levels.
M L Kozhevnikov +2 more
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NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
, 2015 Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J +25 more
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Multiple sclerosis and herpesvirus interaction
Arquivos de Neuro-Psiquiatria, 2013 Multiple sclerosis is the most common autoimmune inflammatory demyelinating disease of the central nervous system, and its etiology is believed to have both genetic and environmental components.
Guilherme Sciascia do Olival +10 more
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