Results 111 to 120 of about 36,154,205 (252)

Epstein‐Barr virus as a driver of lupus: Rethinking triggers in autoimmunity

Rheumatology &Autoimmunity, EarlyView.
Jiekai Tan, Fanlei Hu, Chuanhui Xu
wiley   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes

mBio, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi’s sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes lytic infection of monocytes in
Kurtis M. Host, Sarah R. Jacobs, John A. West, Zhigang Zhang, Lindsey M. Costantini, Charles M. Stopford, Dirk P. Dittmer, Blossom Damania   +7 more
doaj   +1 more source

Human herpesvirus 1 protein US3 induces an inhibition of mitochondrial electron transport

Journal of General Virology, 2006
Previous studies have identified virus proteins that traffic to mitochondria and may affect mitochondrial function. Here, it is reported that Human herpesvirus 1 (HHV-1, herpes simplex virus 1) and influenza virus reduced mitochondrial respiration, whilst Measles virus, cytomegalovirus, coxsackievirus B4 and Feline calicivirus did not.
Mohammad, Derakhshan, Margaret M, Willcocks, Michael A, Salako, George E N, Kass, Michael J, Carter   +4 more
openaire   +2 more sources

Microbiome and Pathobiome Characterization in Farmed Barramundi (Lates calcarifer) During and Post Scale Drop Disease Outbreaks

Journal of Fish Diseases, EarlyView.
ABSTRACT Large‐scale double‐digest RAD sequencing (ddRADseq) datasets generated for genotyping are increasingly available in aquaculture, yet their unmapped reads remain largely unexplored for pathogen surveillance. Here, we evaluated the utility and limitations of repurposing unmapped ddRADseq reads to examine pathogen‐associated and disease ...
Nguyen Thanh Vu, Xueyan Shen, Susan Gibson‐Kueh, Maura Carrai, Celestine Terence, Zhi Weng Josiah Poon, Sarah Priyanka Nelson, Saengchan Senapin, Ha Thanh Dong, Jiun‐Yan Loh, Dean R. Jerry, Jose A. Domingos   +11 more
wiley   +1 more source

CNS INFECTIONS CAUSED BY VIRUSES OF THE HERPESVIRIDAE FAMILY: CASE ANALYSIS IN A TERTIARY INFECTIOUS DISEASES CENTER

Brazilian Journal of Infectious Diseases
Introduction/Objectives: The Herpesviridae family includes viruses with latency capacity, such as HSV-1, HSV-2, VZV, CMV, and Human herpesvirus 6, which can cause neurological manifestations such as meningitis, encephalitis, and encephalomyelitis.
Luís Arthur Brasil Gadelha Farias, Lorena Alves Brito, Bruno Cavalcante Fales de Brito Alves, José Leonardo da Silveira Morais, Osvaldo Mariano Viana Neto, Ednaldo Pereira Lima Sobrinho, Tânia Mara Silva Coelho, Maura Salaroli de Oliveira, Lauro Vieira Perdigão Neto, Antonio Silva Lima Neto   +9 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

ORFeome-based arrays in eukaryotic expression vectors - a new approach to screen for the function of viral proteins [PDF]

, 2005
Since its first description in 1994 by Yuan Chang and Patrick Moore, Kaposi’s sarcoma-associated herpesvirus (KSHV) or Human Herpesvirus 8 (HHV-8) has emerged as a pathogen of international public health importance.
Roupelieva, Maria
core   +1 more source

Herpesvirus-host interactions in neurological diseases: the immunogenetic role of HLA-E

Journal of Virology
Human herpesviruses (HHVs) comprise nine pathogenic members, including herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, human herpesvirus 6A/B, human herpesvirus 7, and Kaposi’s sarcoma ...
Marianne Graninger, Elisabeth Puchhammer-Stöckl, Hannes Vietzen   +2 more
doaj   +1 more source

In Vitro and In Vivo Transactivation of HIV-1 by Human Herpesvirus 6

, 2011
1.1 Latency and reactivation of HIV-1 Since the discovery of human immunodeficiency virus type 1 (HIV-1), there has been a great deal of interest in identifying cofactors that might accelerate the stages of development associated with acquired immunodeficiency syndrome (AIDS).
Ongradi Joseph, Kovesdi Valeria, Nagy Karoly, Matteoli Barbara, Ceccherini-Nelli Luca, Ablashi Dharam   +5 more
openaire   +2 more sources