Results 91 to 100 of about 637,219 (198)

Co‐Delivery of Varicella Zoster Virus gE and gI Dual‐Antigen mRNA Vaccine With CpG‐ODN Elicits Robust Immunity

MedComm, Volume 7, Issue 11, November 2026.
The gE+gI Lmix+CpG‐ODN 1018 vaccine was formulated by combining gE and gI mRNA/LNPs with the TLR9 agonist adjuvant CpG‐ODN 1018. This formulation induces robust humoral and cellular immunity while maintaining a favorable safety profile and physiological stability in mice.
Lingyan Cui, Sibo Zhang, Wenhui Xue, Hongjing Liu, Hong Wang, Hai Li, Yarong Zeng, Huizheng Zhang, Yaohan Li, Minqing Hong, Lin Chen, Jun Zhang, Ying Gu, Shaowei Li, Tingting Li, Ningshao Xia   +15 more
wiley   +1 more source

Active herpesviruses are associated with intensive care unit (ICU) admission in patients pulmonary infection and alter the respiratory microbiome

Frontiers in Microbiology
BackgroundThe Herpesviridae family contains several human-related viruses, which are able to establish colonizing and latency in the human body, posing a significant threat to the prognosis of patients.
Zhiguang Liu, Chun-jian Qi, Yujia Shi, Tianyu Li, Yuan Fang, Qian Zhang, Qian Zhang   +6 more
doaj   +1 more source

Inflammatory Pseudotumour in Common Seal (Phoca vitulina): A Case Report

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A 19‐year‐old intact male common seal (Phoca vitulina) diagnosed with a chronic ulcer. Microbiology identified Vibrio alginolyticus. Radiography noted phalanx alterations. Macroscopic, histopathological, and immunohistochemical examinations revealed a neoplastic origin with a myofibroblastic phenotype. This report describes the first documented case of
Javier M. De Pablo‐Moreno, Rocío Canales, Mireia Mainez, Nicolás Aradilla, Blanca Chinchilla, Néstor Porras, Ignacio Vargas‐Castro, Antonio Rodríguez‐Bertos   +7 more
wiley   +1 more source

Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection

EMBO Reports
To globally profile circRNAs, we employ RNA-Sequencing paired with chimeric junction analysis for alpha-, beta-, and gamma-herpesvirus infection. We find circRNAs are, as a population, resistant to host shutoff. We validate this observation using ectopic
Sarah E Dremel, Takanobu Tagawa, Vishal N Koparde, Carmen Hernandez-Perez, Jesse H Arbuckle, Thomas M Kristie, Laurie T Krug, Joseph M Ziegelbauer   +7 more
doaj   +1 more source

Generation, characterization, and application of caprine herpesvirus 1 secreted glycoprotein D

Microbiology Spectrum
Caprine herpesvirus 1 (CpHV-1), a member of the Herpesvirales order, Herpesviridae family, Alphaherpesvirinae subfamily, and Simplexvirus genus, is classically associated with two distinct clinical syndromes.
Sergio Minesso, Amienwanlen Eugene Odigie, Valentina Franceschi, Simone Taddei, Vittorio Madia, Maria Tempesta, Gaetano Donofrio   +6 more
doaj   +1 more source

Key insights into biosecurity risks, communication preferences and behaviour change drivers among livestock transporters in Australia

Australian Veterinary Journal, Volume 104, Issue 11, Page 755-765, November 2026.
The transportation of livestock poses an increased risk of disease transmission, with transportation vehicles acting as vectors for disease. Biosecurity management within the livestock industry is therefore critical to reduce the risk of disease transmission. This study investigated the current biosecurity practices of stakeholders within the livestock
M Hernandez‐Jover, L Hayes, J Manyweathers, J Bond   +3 more
wiley   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1601-1609, November 2026.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

Reactivation of latent human immunodeficiency virus 1 by human herpesvirus 6 infection.

Acta virologica, 2007
Infection of the ACH-2 line of human leukemic T cells carrying latent Human immunodeficiency virus 1 (HIV-1) with Human herpesvirus 6 (HHV-6) resulted in an increase in reverse transcriptase (RT) activity, a marker of HIV-1 activation, in the culture supernatant. A similar effect was obtained with 12-O-tetradecanoyl-phorbol-13-acetate (TPA).
Y, Isegawa, J, Katahira, K, Yamanishi, N, Sugimoto   +3 more
openaire   +1 more source

Ecology driven patterns of herpesvirus spread in cervids in Poland

Scientific Reports
Cervids are considered as a potential hosts for various human and animal pathogens but studies on herpesvirus infections among these species remain limited.
Wojciech Socha, Artur Jabłoński, Michał K. Krzysiak, Piotr Kubiś, George Russell, Magdalena Larska   +5 more
doaj   +1 more source

Use of bidirectional Mendelian randomization to unveil the association between antibody-mediated immune responses to infectious agents and allergic rhinitis

Human Vaccines & Immunotherapeutics
Allergic rhinitis (AR) is increasingly prevalent, yet diagnostic and therapeutic approaches remain inadequate. Recent studies show links between infectious diseases and noninfectious disorders, but the underlying mechanisms are largely unknown.
Wencan Cao, Xiaxuan Chen, Xinrong Li, Yuxian Wang   +3 more
doaj   +1 more source