Results 1 to 10 of about 22,163,553 (318)

Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection [PDF]

Open Biology, 2016
The majority of T cells encountered by HIV-1 are non-activated and do not readily allow productive infection. HIV-1 Vpr is highly abundant in progeny virions, and induces signalling and HIV-1 LTR transcription.
Kristin Höhne, Ramona Businger, Anouk van Nuffel, Sebastian Bolduan, Herwig Koppensteiner, Ann Baeyens, Jolien Vermeire, Eva Malatinkova, Bruno Verhasselt, Michael Schindler   +9 more
doaj   +1 more source

HIV Stigma and Missed Medications in HIV-Positive People in Five African Countries. [PDF]

, 2009
The availability of antiretroviral medications has transformed living with HIV infection into a manageable chronic illness, and high levels of adherence are necessary. Stigma has been identified as one reason for missing medication doses.
Dlamini, Priscilla S., Mullan, Joseph, Holzemer, William L., Kohi, Thecla W, Chirwa, M., Wantland, Dean, Makoae, L.N, Naidoo, J., Makoae, Lucy N., Dlamini, Priscilla S, Makoae, Lucy N, Dlamini, P.S, Holzemer, W.L, Uys, L.R, Wantland, D., Greeff, M., Chirwa, Maureen, Mullan, J., Kohi, Thecla W., Naidoo, Joanne, Uys, Leana R, Holzemer, William L, Greeff, Minrie, Uys, Leana R., Kohi, T.W   +24 more
core   +1 more source

HIV-1 provirus transcription and translation in macrophages differs from pre-integrated cDNA complexes and requires E2F transcriptional programs

Virulence, 2022
HIV-1 cDNA pre-integration complexes persist for weeks in macrophages and remain transcriptionally active. While previous work has focused on the transcription of HIV-1 genes; our understanding of the cellular milieu that accompanies viral production is ...
Albebson L. Lim, Philip Moos, Christopher D. Pond, Erica C. Larson, Laura J. Martins, Matthew A. Szaniawski, Vicente Planelles, Louis R. Barrows   +7 more
doaj   +1 more source

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report

, 2010
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G, Wolf, Timo, Schnierle Barbara S, Schnierle, Barbara S, Thielen, A., Krause, B., Werner, A., Schnierle, Barbara, Christel Kamp, Bravo, I., Winskowsky, Gudrun, Albrecht Werner, Neumann, B., Thielen, Alexander, Werner Albrecht, Krause Birgit, Kamp Christel, Timo Wolf, Wolf, T., Thielen Alexander, Winskowsky, G., Kraus, Benjamin, Wolf Timo, Werner, Albrecht, Gudrun Winskowsky, Alexander Thielen, Neumann, Britta, Birgit Krause, Bravo, Ignacio G., Neumann Britta, Kraus, B., Kamp, Christel, Kamp, C., Ignacio G Bravo, Barbara S Schnierle, Krause, Birgit, Bravo, Ignacio G, Winskowsky Gudrun, Kraus Benjamin, Britta Neumann, Schnierle, B., Benjamin Kraus   +41 more
core   +1 more source

Immune reconstruction effectiveness of combination antiretroviral therapy for HIV-1 CRF01_AE cluster 1 and 2 infected individuals

Emerging Microbes and Infections, 2022
There are great disparities of the results in immune reconstruction (IR) of the HIV-1 infected patients during combined antiretroviral therapy (cART), due to both host polymorphisms and viral genetic subtypes.
Kang Li, Huanhuan Chen, Jianjun Li, Yi Feng, Guanghua Lan, Shujia Liang, Meiliang Liu, Abdur Rashid, Hui Xing, Zhiyong Shen, Yiming Shao   +10 more
doaj   +1 more source

Transmission of HIV-1 infection in sub-Saharan Africa and effect of elimination of unsafe injections [PDF]

, 2004
During the past year, a group has argued that unsafe injections are a major if not the main mode of HIV-1 transmission\ud in sub-Saharan Africa. We review the main arguments used to question the epidemiological interpretations on the lead\ud role of ...
Heimer, R., Kapiga, S. H., De Cock, Kevin M, Williams, B. G., Hayes, R. J., Kapiga, H.Said, Calleja, Jesus Garcia, Ghys, P. D., Garnett, Geoff P, Hayes, Richard J, Buve, Anne, Boerma, J.Ties, Schmid, G. P., Garnet, P.Geoff, Cock, M.De Kevin, Schmid, George P, Garnet, G. P., Whitworth, James A, Calleja, J. G., Kapiga, Saidi H, Mugyenyi, Peter, Zaba, B., Whitworth, J. A., Ghys, D.Peter, Buvé, A., De Cock, K. M., Williams, G.Brian, Zaba, Basia, Hankins, C., Boerma, J Ties, Schmid, P.George, Heimer, Robert, Mugyenyi, P., Williams, Brian G, Hankins, Catherine, Hayes, J.TRichard, Boerma, J. T., Ghys, Peter D, Whitworth, A.James   +38 more
core   +1 more source

Landelijke database Stichting hiv monitoring

, 2023
Door de minister van VWS zijn in totaal 24 erkende hiv-behandelcentra of sub-centra aangewezen die samenwerken met Stichting hiv monitoring (SHM) om data te verzamelen van mensen  met hiv en in zorg zijn in een hiv-behandelcentrum in Nederland. Daarnaast
Stichting hiv monitoring (SHM)
core  

Cell-free (RNA) and cell-associated (DNA) HIV-1 and postnatal transmission through breastfeeding [PDF]

, 2012
<p>Introduction - Transmission through breastfeeding remains important for mother-to-child transmission (MTCT) in resource-limited settings. We quantify the relationship between cell-free (RNA) and cell-associated (DNA) shedding of HIV-1 virus in ...
Van de Perre, P, James Ndirangu, Ndirangu James, Ruth M. Bland, Van de Perre Philippe, Ruth M Bland, Thorne, C., Danaviah, S, Thorne Claire, Newell Marie-Louise, Newell, M.-L., Viljoen, J., Ndirangu, J., Newell, M-L, Thorne, C, Van de Perre, P., Danaviah Siva, Bland, R.M., Philippe Van de Perre, Viljoen, J, Marie-Louise Newell, Ndirangu, J, Claire Thorne, Bland, RM, Danaviah, S., Siva Danaviah, Viljoen Johannes, Bland Ruth M., Johannes Viljoen   +28 more
core   +1 more source

The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Lens-epithelium-derived growth-factor (LEDGF/p75)-binding site on HIV-1 integrase (IN), is an attractive target for antiviral chemotherapy. Small-molecule compounds binding to this site are referred as LEDGF-IN inhibitors (LEDGINs).
Da-Wei Zhang, Hao-Li Yan, Xiao-Shuang Xu, Lei Xu, Zhi-Hui Yin, Shan Chang, Heng Luo   +6 more
doaj   +1 more source

Mapping Transmission Dynamics and Drug Resistance Surveillance in the Cyprus HIV-1 Epidemic (2017–2021)

Viruses
The human immunodeficiency virus type 1 (HIV-1) epidemic has been a major public health threat on a global scale since the early 1980s. Despite the introduction of combination antiretroviral therapy (cART), the incidence of new HIV-1 infections continues
Cicek Topcu, Bram Vrancken, Johana Hezka Rodosthenous, David van de Vijver, Georgios Siakallis, Philippe Lemey, Leondios G. Kostrikis   +6 more
doaj   +1 more source