Results 11 to 20 of about 31,026,669 (309)

Characteristics, immunological response & treatment outcomes of HIV-2 compared with HIV-1 & dual infections (HIV 1/2) in Mumbai. [PDF]

, 2010
BACKGROUND AND OBJECTIVES: Information available on HIV-2 and dual infection (HIV-1/2) is limited. This study was carried out among HIV positive individuals in an urban referral clinic in Khar, Mumbai, India, to report on relative proportions of HIV-1 ...
Manzi, M, Harries, AD, Rony, Zachariah, Ladomirska, Joanna, Wilson, N, Bhanumati, Varghese, Alaka, Deshpande, Homa, Mansoor, Chiara, Montaldo   +8 more
core   +6 more sources

HIV-1 Prevention for HIV-1 Serodiscordant Couples [PDF]

Current HIV/AIDS Reports, 2012
A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling ...
Curran, K, Baeten, JM, Coates, TJ, Kurth, A, Mugo, NR, Celum, C   +5 more
openaire   +2 more sources

HIV-1 transmission and acute HIV-1 infection [PDF]

British Medical Bulletin, 2001
An understanding of the central events in the transmission of HIV-1 infection is critical to the development of effective strategies to prevent infection. Although the main routes of transmission have been known for some time, surprisingly little is known about the factors that influence the likelihood of transmitting or acquiring HIV-1 infection. Once
Hansasuta, P, Rowland-Jones, S
openaire   +2 more sources

Attomolar Detection of HIV-1 With Label-Free RCA-rCRISPR on Smartphone. [PDF]

Adv Sci (Weinh)
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Mohammad N, Steksova A, Tang Y, Huang L, Velayati A, Zhang S, Dey Poonam A, Jamalzadegan S, Breen M, Chen H, Bagi M, Jiang G, Wei Q.   +12 more
europepmc   +2 more sources

Validation of replicative phenotyping to detect and assign HIV-1 resistance in clinical specimens [PDF]

, 2009
The ability of HIV-1 to develop resistance to antiretroviral drugs has limited the overall efficacy of combination therapy to suppress viral replication.
Louvel, Séverine
core   +1 more source

HIV-1 at 25 [PDF]

Cell, 2008
In 1981, the acquired immunodeficiency syndrome (AIDS) appeared insidiously and mystified doctors and scientists alike. No one could have predicted then that it would become, arguably, the worst plague in human history. Today, 33 million persons are living with infection by the human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS ...
Ho, David D., Bieniasz, Paul D.
openaire   +2 more sources

Similar But Different: Integrated Phylogenetic Analysis of Austrian and Swiss HIV-1 Sequences Reveal Differences in Transmission Patterns of the Local HIV-1 Epidemics [PDF]

, 2022
OBJECTIVES Phylogenetic analyses of two or more countries allow to detect differences in transmission dynamics of local HIV-1 epidemics beyond differences in demographic characteristics.
Klimkait, Thomas; https://orcid.org/, Alexander Egle, Perreau, M., Egle, Alexander, Huber, Michael; https://orcid.org/, Chaudron, S.E., Swiss HIV Cohort Study,, Battegay, M., Hirsch, Hans, Jürg Böni, Calmy, Alexandra, Chaudron, Sandra E; https://orcid.org/, Nguyen, H., Swiss HIV Cohort Study, Günthard, Huldrych F., Calmy, Alexandra; https://orcid.org/, Huyen Nguyen, Ramette, A., Schmid, P., Angela Öllinger, Kouyos, R.D., Öllinger, Angela, Yerly, S., Zangerle, Robert, Scherrer, A., Huber, Michael, Patrick Schmid, Calmy, A., Enos Bernasconi, Günthard, Huldrych F, Kouyos, Roger D., Cavassini, M., Kouyos, R. D., Bernhard Haas, Böni, Jürg, Thomas Klimkait, Böni, Jürg; https://orcid.org/, Sarcletti, M., Chaudron, S. E., Bernasconi, Enos, Austrian HIV Cohort Study, Alexandra Scherrer, Gunthard, H. F., Kusejko, K., Günthard, Huldrych F; https://orcid.org/, Baharak Babouee Flury, Katharina Kusejko, Ramette, Alban; https://orcid.org/, Ramette, Alban, Cavassini, Matthias; https://orcid.org/, Kusejko, Katharina, Klimkait, T., Katharina Grabmeier-Pfistershammer, Perreau, Matthieu, Nguyen, Huyen; https://orcid.org/, Mario Sarcletti, Sandra E. Chaudron, Cavassini, Matthias, Battegay, Manuel, Yerly, Sabine, Roger D. Kouyos, Nguyen, Huyen, Yerly, Sabine; https://orcid.org/, Bernasconi, Enos; https://orcid.org/, Battegay, Manuel; https://orcid.org/, Hans Hirsch, Flury, Baharak Babouee, Schmid, Patrick, Zangerle, Robert; https://orcid.org/, Alexandra Calmy, Klimkait, Thomas, Haas, B., Matthieu Perreau, Grabmeier-Pfistershammer, Katharina, Tschumi, N., Robert Zangerle, Babouee Flury, B., Nadine Tschumi, Yerly Ferrillo, Sabine, Alban Ramette, Kusejko, Katharina; https://orcid.org/, Tschumi, Nadine, Tschumi, Nadine; https://orcid.org/, Bernasconi, E., Scherrer, Alexandra, Huber, M., Hirsch, H., Chaudron, Sandra E, Zangerle, R., Michael Huber, Chaudron, Sandra E., Öllinger, A., Hirsch, Hans H; https://orcid.org/, Haas, Bernhard, Huldrych F. Günthard, Kouyos, Roger D, Grabmeier-Pfistershammer, K., Sabine Yerly, Kouyos, Roger D; https://orcid.org/, Günthard, H.F., Manuel Battegay, Boni, J., Flury, B.B., Sarcletti, Mario, Austrian HIV Cohort Study,, Matthias Cavassini, Egle, A.   +106 more
core   +2 more sources

Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription [PDF]

Retrovirology, 2006
Abstract Background Transcription of HIV-1 genes is activated by HIV-1 Tat protein, which induces phosphorylation of RNA polymerase II (RNAPII) C-terminal domain (CTD) by CDK9/cyclin T1. Earlier we showed that CDK2/cyclin E phosphorylates HIV-1 Tat in vitro.
Gordeuk Victor R, Southerland William, Klase Zachary, Charles Sharroya, Jackson Angela, Jerebtsova Marina, Berro Reem, Ammosova Tatyana, Kashanchi Fatah, Nekhai Sergei   +9 more
openaire   +3 more sources

Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway

Viruses, 2016
The mammalian target of rapamycin (mTOR) is a central regulator of gene expression, translation and various metabolic processes. Multiple extracellular (growth factors) and intracellular (energy status) molecular signals as well as a variety of stressors
Valerie Le Sage, Alessandro Cinti, Raquel Amorim, Andrew J. Mouland   +3 more
doaj   +1 more source

Durable natural killer cell response after three doses of SARS-CoV-2 inactivated vaccine in HIV-infected individuals

Chinese Medical Journal, 2023
. Background:. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine can induce a potent cellular and humoral immune response to protect against SARS-CoV-2 infection.
Xiaodong Yang, Xiuwen Wang, Xin Zhang, Haifeng Ding, Hu Wang, Tao Huang, Guanghui Zhang, Junyi Duan, Wei Xia, Bin Su, Cong Jin, Hao Wu, Tong Zhang, Sihan Zhou, Xiuyuan Hao   +14 more
doaj   +1 more source