Results 41 to 50 of about 22,166,132 (318)

Temporal trends and clinical outcomes of antiretroviral therapy initiation and regimens in treatment-naive people with HIV: A real-world study at a tertiary specialist hospital in Beijing, China

Infectious Diseases & Immunity
. Background:. The WHO and international treatment guidelines recommend rapid initiation of antiretroviral therapy (ART) for all treatment-naive (TN) people living with human immunodeficiency virus (HIV) (PLWH).
Jiantao Fu, Ying Liu, Yifan Guo, Jing Chen, Hongxin Zhao, Haijuan Wang   +5 more
doaj   +1 more source

Concurrent sexual partnerships and HIV prevalence in five urban communities of sub-Saharan Africa. [PDF]

, 2001
OBJECTIVE: To estimate parameters of concurrent sexual partnerships in five urban populations in sub-Saharan Africa and to assess their association with levels of HIV infection and other sexually transmitted infections (STI).
Lagarde, E., Ferry, B., N'Doye, I., Sukwa, T, Buvé, A, Laourou, M, Akam, E, Sukwa, T., Chege, J, N'Doye, I, Auvert, B, Maury, B, Morison, L., Caraël, M, Maury, E., Lagarde, E, Auvert, B., Chege, J., Buvé, A., Study Group on Heterogeneity of HIV Epidemics in African Cities, Caraël, M., Akam, E., Laourou, M., Ferry, B, Morison, L   +24 more
core   +1 more source

Study of the specific toxic effects of the substance 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil, the original non-nucleoside inhibitor of human immunodeficiency virus type 1 (Retroviridae; Orthoretrovirinae; Lentivirus: Human immunodeficiency virus 1) reverse transcriptase

Вопросы вирусологии, 2021
Introduction. Combination antiretroviral therapy is currently the main component of treatment for human immunodeficiency virus (HIV) infected patients.
E. A. Gaidai, K. L. Kryshen, E. A. Jain (Korsakova), D. V. Demchenko, D. R. Kargopol’tseva, A. E. Katel’nikova, D. S. Gaidai, V. Yu. Balabanyan   +7 more
doaj   +1 more source

Landelijke database Stichting hiv monitoring [PDF]

, 2023
Door de minister van VWS zijn in totaal 24 erkende hiv-behandelcentra of sub-centra aangewezen die samenwerken met Stichting hiv monitoring (SHM) om data te verzamelen van mensen  met hiv en in zorg zijn in een hiv-behandelcentrum in Nederland. Daarnaast
Stichting hiv monitoring (SHM)
core  

HIV-1 Nef: at the crossroads [PDF]

Retrovirology, 2008
The development of anti-virals has blunted the AIDS epidemic in the Western world but globally the epidemic has not been curtailed. Standard vaccines have not worked, and attenuated vaccines are not being developed because of safety concerns. Interest in attenuated vaccines has centered on isolated cases of patients infected with HIV-1 containing a ...
Garcia J Victor, Foster John L
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Outcomes for efavirenz versus nevirapine-containing regimens for treatment of HIV-1 infection: a systematic review and meta-analysis. [PDF]

, 2013
INTRODUCTION: There is conflicting evidence and practice regarding the use of the non-nucleoside reverse transcriptase inhibitors (NNRTI) efavirenz (EFV) and nevirapine (NVP) in first-line antiretroviral therapy (ART). METHODS: We systematically reviewed
Pillay, Prinitha, Prinitha Pillay (435496), Pillay Prinitha, Prinitha Pillay, Ford Nathan, Shubber Zara, Shubber, Zara, Ford, Nathan, Rashida A. Ferrand, Ferrand Rashida A., Nathan Ford, Ferrand, Rashida A, Nathan Ford (59436), Zara Shubber (279389), Rashida A. Ferrand (253679), Rashida A Ferrand, Zara Shubber   +16 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Characteristics, Immunological Response & Treatment Outcomes of HIV-2 Compared with HIV-1 & Dual Infections (HIV 1/2) in Mumbai [PDF]

, 2010
Information available on HIV-2 and dual infection (HIV-1/2) is limited. This study was carried out among HIV positive individuals in an urban referral clinic in Khar, Mumbai, India, to report on relative proportions of HIV-1, HIV-2 and HIV-1/2 and ...
Manzi, M, Harries, AD, Rony, Zachariah, Ladomirska, Joanna, Harries, A D, Wilson, N, Bhanumati, Varghese, Alaka, Deshpande, Homa, Mansoor, Chiara, Montaldo   +9 more
core   +1 more source