Results 51 to 60 of about 22,166,132 (318)
Breast Milk from Tanzanian Women has Divergent Effects on Cell-Free and Cell-Associated HIV-1 Infection in Vitro. [PDF]
, 2012 Transmission of HIV-1 during breastfeeding is a significant source of new pediatric infections in sub-Saharan Africa. Breast milk from HIV-positive mothers contains both cell-free and cell-associated virus; however, the impact of breast milk on HIV-1 ...Ruth I Connor, Alexandra L Howell, Molly L Housman, Lee, F.V, Housman, M.L., Zain-Ul-Abideen Muhammad, Frederick V Lee, Zain-Ul-Abideen, M., Connor, R.I, Connor Ruth I., Zain-Ul-Abideen, Muhammad, Lyimo, M.A., Howell, Alexandra L, Lyimo, Magdalena A, Magdalena A Lyimo, Howell Alexandra L., Housman, Molly L, Mosi, M.N, Muhammad Zain-Ul-Abideen, Howell, A.L, Lee, Frederick V, Mosi, Matilda Ngarina, Matilda Ngarina Mosi, Connor, Ruth I, Lyimo Magdalena A., Housman Molly L., Mosi Matilda Ngarina, Lee Frederick V. +27 morecore +1 more sourceHIV-1 detection in the olfactory mucosa of HIV-1-infected participants
AIDS, 2019 HIV infection chronically affects the central nervous system (CNS). Olfactory mucosa is a unique site in the respiratory tract that is directly connected to the CNS; thus we wanted to evaluate olfactory mucosa as a surrogate of CNS sampling.We conducted a preliminary study examining HIV populations and susceptible cells in the olfactory mucosa ...Bertero, Luca, Joseph, Sarah Beth, Trunfio, Mattia, Allice, Tiziano, Catera, Sebastiano, Imperiale, Daniele, Cassoni, Paola, Kincer, Laura Pesci, Pirriatore, Veronica, Ghisetti, Valeria, Amasio, Enrica, Zanusso, Gianluigi, Bonora, Stefano, Di Perri, Giovanni, Calcagno, Andrea +14 moreopenaire +4 more sourcesBiophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the Inbar Yosibash, Raya Sorkinwiley +1 more sourceCommon Genetic Variation and the Control of HIV-1 in Humans [PDF]
, 2009 To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects.Cirulli, Elizabeth T, Gunthard, HF, Thomas J. Urban, Andrew J. Mcmichael, Guenthard, Huldrych F., Gumbs, CE, Feng, S, Feng, Sheng, De Luca Andrea, McMichael, A. J, Obel, N., Miró Meda, José M. (José María), 1956-, O'Brien SJ, Haynes BF, Haynes, B. F, Ge, D., Letvin, Norman L., Jeremy J. Martinson, Martinson, J. J, Beckmann, J S, Smith, Jason P., Descombes P, Cozzi-Lepri, A, Jacobson, L P, Margolick, J B, Cirulli, E. T, Shianna, K V, Niels Obel, Ge Dongliang, Simon Mallal, Wolinsky, Steven M, Jacques S Beckmann, Urban TJ, O'Brien, S J, Antonarakis, S.E., Wolinsky, S. M, Bruno Ledergerber, Telenti, A., Urban, T.J., Ge, DL, Detels, R, Javier Martinez-Picado, Günthard, H F, Letvin, NL, Jason P. Smith, Zhang, Kunlin, Cirulli Elizabeth T., Colombo S, Colombo, S, McMichael, AJ, Feng S, McMichael, Andrew J., Joseph B. Margolick, Mussini, C., Cozzi-Lepri Alessandro, Sheng Feng, Descombes Patrick, Letvin NL, Goldstein, DB, Barton F. Haynes, Fellay, J., Jacobson, Lisa, Goldstein, D. B., Feng, S., Martínez Picado, Francisco Javier, Antonella Castagna, Haynes, BF, Telenti, A, Jacobson, L.P., Shianna, K.V., Fellay Jacques, Miro, José M, Antonarakis Stylianos E., Mcmichael, Andrew, David B Goldstein, Gumbs, C. E, Jacobson, Lisa P., Miro, José M., Jason P Smith, Miro, J.M., Cirulli, Elizabeth T., Antonarakis SE, Shianna, Kevin V, Easterbrook, P, Martinson, Jeremy J, Stylianos E Antonarakis, Gumbs, Curtis E, O'Brien, Stephen J, Mary Carrington, Mallal, S, Zhang, K, Curtis E. Gumbs, Castagna, A., Martinson, J J, Detels, Roger, Wolinsky SM, Easterbrook, Philippa, Haynes, Barton F, Letvin, N L, Letvin, N. L, Colombo, Sara, Martinez Picado J, Gumbs CE, Cozzi Lepri A, Haynes, B F, Smith, J P, Letvin, Norman L, Jacques Fellay, Ledergerber B, Telenti, Amalio, Carrington M, Dalmau, J., Mallal, Simon, De Luca, Andrea, Easterbrook Philippa, Martinez-Picado Javier, Wolinsky, Steven, Dalmau J, Beckmann, Jacques, Jacobson, L. P, O'Brien, S. J, Margolick, Joseph B, NIAID Center for HIV/AIDS Vaccine Immunology, Amalio Telenti* David B. Goldstein, Miro, J. M, Dongliang Ge, Margolick JB, Shianna, K. V, Cozzi-Lepri, Alessandro, Smith, J. P., Elizabeth T Cirulli, Amalio Telenti, Jacobson Lisa P., Carrington Mary, Goldstein, David B, Huldrych F. Günthard, Gumbs Curtis E., De, Luca A., Feng Sheng, Urban, TJ, Carrington, M, Antonarakis, Stylianos E, Kevin V Shianna, Ledergerber, B., Martinson Jeremy J., Martinson, Jeremy J., Goldstein, David B., Urban, T J, Urban Thomas J., Günthard, H. F, Margolick Joseph B., Cristina Mussini, Elizabeth T, Ge, Dongliang, Urban, Thomas J., Stylianos E. Antonarakis, Günthard, H.F., McMichael AJ, Wolinsky Steven M., Telenti Amalio, Martinez-Picado, J, Miro, J M, Cirulli ET, Huldrych F Günthard, Urban, Thomas J, Stephen J O'Brien, Martinez-Picado, Javier, Steven M. Wolinsky, Zhang K, Easterbrook P, Cirulli, Elisabeth T., Curtis E Gumbs, José M Miro, Shianna Kevin V., Jacobson, Lisa P, Wolinsky, S M, Lisa P. Jacobson, Günthard HF, Martinson, J.J., Norman L Letvin, Mallal Simon, Ledergerber, B, McMichael, A.J., McMichael, Andrew J, Smith, J.P., Gumbs, Curtis E., Günthard, Huldrych F., Smith, JP, Fellay, Jacques, Beckmann, Jacques S., Antonarakis, SE, Miro JM, Ledergerber, Bruno, Telenti A, Lisa P Jacobson, Wolinsky, Steven M., Roger Detels, Antonarakis, S E, Urban, T. J, Mallal, S., Günthard, Huldrych F, Obel, N, Cirulli, E T, Martinson JJ, Patrick Descombes, Ledergerber Bruno, Haynes Barton F., Mussini, C, Philippa Easterbrook, Descombes, P, Fellay J, Goldstein David B., Fellay, J, Margolick, Joseph B., Goldstein, D B, Steven M Wolinsky, Zhang Kunlin, Castagna A, Smith, Jason P, Descombes, Patrick, Gumbs, C E, Letvin Norman L., Goldstein, D.B., Margolick, JB, Smith JP, Smith, J. P, Beckmann, J. S, Wolinsky, S.M., Beckmann, Jacques S, Andrew J McMichael, Andrea De Luca, Beckmann, J.S., Jeremy J Martinson, Beckmann JS, NIAID Ctr HIV AIDS Vaccine Immunol, Shianna, KV, Haynes, Barton F., Gumbs, C.E., Jacques S. Beckmann, Ge D, McCarthy, M.I., Ge, D, McMichael Andrew J., Cirulli, ET, O'Brien, Stephen J., Norman L. Letvin, O\u27Brien, Stephen J., Dalmau Judith, Cozzi-Lepri, A., Haynes, B.F., Detels R, Ro Cozzi-lepri, Smith Jason P., Margolick, J.B., Günthard Huldrych F., Gumbs, Curtis, Zhang, KL, Colombo, S., Margolick, Joseph, De Luca A, Margolick, J. B, Beckmann Jacques S., O'Brien, Stephen, Shianna, Kevin V., Barton F Haynes, Dalmau, J, Kevin V. Shianna, Jacobson, LP, Wolinsky, SM, Martinez-Picado, J., Antonarakis, S. E, Mallal S, Carrington, Mary, Colombo Sara, Zhang, K., Letvin, N.L., Castagna, A, Obel, Niels, Mussini, Cristina, Detels Roger, O'Brien, S.J., Carrington, M., Obel Niels, Cirulli, E.T., Antonarakis, Stylianos E., Goldstein DB, Thomas J Urban, Descombes, P., Castagna, Antonella, Jose ́ M. Miro, Miro, JM, Sara Colombo, Judith Dalmau, O'Brien Stephen J., De Luca, A., Kunlin Zhang, Castagna Antonella, De Luca, A, Beckmann, JS, Stephen J. O’brien, Mussini Cristina, Easterbrook, P., Jacobson LP, Miro José M., Martinson, JJ, NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI), Obel N, O'Brien, SJ, Shianna KV, Dalmau, Judith, McMichael, A J, Letvin, Norman Lee, Joseph B Margolick, Detels, R., Alessandro Cozzi-Lepri +314 morecore +1 more sourceSensor Sensibility—HIV-1 and the Innate Immune Response
Cells, 2020 Innate immunity represents the human immune system’s first line of defense against a pathogenic intruder and is initiated by the recognition of conserved molecular structures known as pathogen-associated molecular patterns (PAMPs) by specialized ...Xin Yin, Simon Langer, Zeli Zhang, Kristina M. Herbert, Sunnie Yoh, Renate König, Sumit K. Chanda +6 moredoaj +1 more sourceThe Role of HIV-1 DNA as an Additional Marker of HIV-1 Infection
Current HIV Research, 2009 After the infusion of HIV-1 virus into a host cell, RNA is reverse transcribed to dsDNA, which persists intracellular to the infected cell in a variety of forms. Numerous in-house assays have been developed for the quantification of the different cellular HIV-1 DNA forms; these implement conventional or real-time PCR methodology.Beloukas, A., Paraskevis, D., Psichogiou, M., Hatzakis, A. +3 moreopenaire +3 more sourcesPhosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind +9 morewiley +1 more sourceCost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. [PDF]
, 2000 Background Access to HIV-1 voluntary counseling and testing (VCT) is severely limited in less-developed countries. We undertook a multisite trial of HIV-1 VCT to assess its impact, cost, and cost-effectiveness in less-developed country settings.\ud ...Sangiwa , G, Balmer, D, Sweat , M, Furlonge , C, Coates , T, Kamenga , C, Gregorich , S, Grinstead, O +7 morecore Severe acute respiratory syndrome coronavirus 2-specific T-cell responses are induced in people living with human immunodeficiency virus after booster vaccination
Chinese Medical Journal.
Background:. T-cell-mediated immunity is crucial for the effective clearance of viral infection, but the T-cell-mediated immune responses that are induced by booster doses of inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...Xiuwen Wang, Yongzheng Li, Junyan Jin, Xiaoran Chai, Zhenglai Ma, Junyi Duan, Guanghui Zhang, Tao Huang, Xin Zhang, Tong Zhang, Hao Wu, Yunlong Cao, Bin Su, Yanjie Yin +13 moredoaj +1 more source