Results 31 to 40 of about 22,166,132 (318)

Everything counts - a method to determine viral suppression among people living with HIV using longitudinal data for the HIV care continuum - results of two large, German, multi-center real-life cohort studies over 20 years (1999–2018)

BMC Public Health, 2021
Background The aim of this study was to develop a standardized method to reconstruct persons’ individual viral load (VL) courses to determine viral suppression and duration of viremia for the HIV care continuum in Germany using longitudinal cohort data ...
Daniel Schmidt, Christian Kollan, Matthias Stoll, Osamah Hamouda, Viviane Bremer, Tobias Kurth, Barbara Bartmeyer, the HIV-1 Seroconverter cohort, the ClinSurv HIV cohort   +8 more
doaj   +1 more source

Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. [PDF]

, 2010
BACKGROUND: Both T-cell activation during early HIV-1 infection and soluble markers of immune activation during chronic infection are predictive of HIV disease progression.
van Loggerenberg, Francois, Passmore, Jo-Ann Shelley., Burgers, Wendy A, Passmore, Jo-Ann S., Loggerenberg, Francois van, Bebell, Lisa M., Roberts, Lindi., Mlisana, Koleka Patience., Burgers, Wendy A., Passmore, Jo-Ann S, Roberts, Lindi, Mlisana, Koleka, Djoba Siawaya, Joel Fleury., Abdool Karim, Salim Safurdeen., Djoba Siawaya, Joel F., Williamson, Carolyn., Little, Francesca., Abdool Karim, Quarraisha, Mlisana, Koleka P., Djoba Siawaya, Joel F, Bebell, Lisa M, Karim, Quarraisha Abdool, Williamson, Carolyn, Walzl, Gerhard, Abdool Karim, Quarraisha., Abdool Karim, Salim, van Loggerenberg, Francois., Karim, Salim S Abdool, Little, Francesca, Walzl, Gerhard.   +29 more
core   +1 more source

The HIV-1 transmission bottleneck [PDF]

Retrovirology, 2017
It is well established that most new systemic infections of HIV-1 can be traced back to one or a limited number of founder viruses. Usually, these founders are more closely related to minor HIV-1 populations in the blood of the presumed donor than to more abundant lineages.
Samuel Mundia Kariuki, Philippe Selhorst, Kevin K. Ariën, Jeffrey R. Dorfman   +3 more
openaire   +4 more sources

Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression [PDF]

, 2010
Background: Previously, we showed that glioma pathogenesis related protein (GliPR) is induced in CEM T cells upon HIV-1 infection in vitro. To examine whether GliPR plays a role as HIV dependency factor (HDF), we tested the effect of GliPR suppression by
Scheuring Urban J, Oliver G Ottmann, Dietrich, Ursula, Capalbo Gianni, Scheuring, Urban J., Ursula Dietrich, Ottmann, Oliver G., Dietrich Ursula, Gianni Capalbo, Urban J Scheuring, Hoelzer, Dieter (Prof. Dr.), Müller-Kuller Thea, Hoelzer Dieter, Ottmann Oliver G, Dieter Hoelzer, Thea Müller-Kuller, Capalbo, Gianni, Müller-Kuller, Thea   +17 more
core   +1 more source

Host mRNA decay proteins influence HIV-1 replication and viral gene expression in primary monocyte-derived macrophages

Retrovirology, 2019
Background Mammalian cells harbour RNA quality control and degradative machineries such as nonsense-mediated mRNA decay that target cellular mRNAs for clearance from the cell to avoid aberrant gene expression.
Shringar Rao, Raquel Amorim, Meijuan Niu, Yann Breton, Michel J. Tremblay, Andrew J. Mouland   +5 more
doaj   +1 more source

Assessment of HIV-1 entry inhibitors by MLV/HIV-1 pseudotyped vectors [PDF]

, 2005
Background: Murine leukemia virus (MLV) vector particles can be pseudotyped with a truncated variant of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) and selectively target gene transfer to human cells expressing both CD4 and an ...
Sandra Siegert, Barbara S Schnierle, Schnierle Barbara S, Wagner Ralf, Ralf Wagner, Thaler Sonja, Siegert, Sandra, Schnierle, Barbara, Siegert Sandra, Thaler, Sonja, Wagner, Ralf, Sonja Thaler   +11 more
core   +1 more source

Anaemia in acute HIV-1 subtype C infection. [PDF]

, 2007
BACKGROUND: The high prevalence of anaemia and the increased morbidity and mortality associated with anaemia during AIDS has been well described yet there has been little information about anaemia and changes in haemoglobin levels during acute and early ...
Auld, Sara C, van Loggerenberg, Francois, Auld Sara C., Loggerenberg, Francois van, Sobieszczyk Magdalena E., Abdool Karim Salim S., Grobler Anneke, Grobler, Anneke, Anneke Grobler, Auld, Sara C., Itua Iriogbe, Mlisana, Koleka Patience., Iriogbe, Itua, Sobieszczyk, Magdalena E, van Loggerenberg, F, Mlisana, K, Iriogbe, Itua., Salim S Abdool Karim, Mlisana, Koleka, Auld, SC, Abdool Karim, Salim Safurdeen., Sobieszczyk, ME, Grobler, A, Magdalena E Sobieszczyk, Williamson, Carolyn., Carolyn Williamson, Francois van Loggerenberg, Abdool Karim, Salim S, Sobieszczyk, Magdalena E., Iriogbe, I, Williamson Carolyn, Abdool Karim, SS, Sara C Auld, Team, for the CAPRISA Acute Infection Study, Williamson, Carolyn, Williamson, C, Grobler, Anna Christina., van Loggerenberg, Francois., van Loggerenberg Francois, Karim, Salim S Abdool, Koleka Mlisana, Iriogbe Itua, Mlisana Koleka, CAPRISA Acute Infection Study Team   +43 more
core   +1 more source

Acute HIV-1 Infection [PDF]

New England Journal of Medicine, 2011
In 2009, the United Nations estimated that 33.2 million people worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6 million people had been newly infected.1 The need for effective HIV-1 prevention has never been greater.
Cohen, MS, Shaw, G, Mcmichael, A, Haynes, B   +3 more
openaire   +3 more sources

Genetic diversity and drug resistance mutations of HIV-1 in Leningrad Region

Журнал микробиологии, эпидемиологии и иммунобиологии, 2022
Introduction. The spread of the human immunodeficiency virus type 1 (HIV-1) has become a global concern and has approached the pandemic status. St.
A. N. Shchemelev, A. V. Semenov, Yu. V. Ostankova, E. B. Zueva, D. E. Valutite, D. A. Semenova, V. S. Davydenko, A. A. Totolian   +7 more
doaj   +1 more source

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report [PDF]

, 2010
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G, Wolf, Timo, Schnierle Barbara S, Schnierle, Barbara S, Thielen, A., Krause, B., Werner, A., Schnierle, Barbara, Christel Kamp, Bravo, I., Winskowsky, Gudrun, Albrecht Werner, Neumann, B., Thielen, Alexander, Werner Albrecht, Krause Birgit, Kamp Christel, Timo Wolf, Wolf, T., Thielen Alexander, Winskowsky, G., Kraus, Benjamin, Wolf Timo, Werner, Albrecht, Gudrun Winskowsky, Alexander Thielen, Neumann, Britta, Birgit Krause, Bravo, Ignacio G., Neumann Britta, Kraus, B., Kamp, Christel, Kamp, C., Ignacio G Bravo, Barbara S Schnierle, Krause, Birgit, Bravo, Ignacio G, Winskowsky Gudrun, Kraus Benjamin, Britta Neumann, Schnierle, B., Benjamin Kraus   +41 more
core   +1 more source