Results 31 to 40 of about 22,163,553 (318)

Depicting HIV-1 Transcriptional Mechanisms: A Summary of What We Know

Viruses, 2020
Despite the introduction of combinatory antiretroviral therapy (cART), HIV-1 infection cannot be cured and is still one of the major health issues worldwide. Indeed, as soon as cART is interrupted, a rapid rebound of viremia is observed.
Antoine Dutilleul, Anthony Rodari, Carine Van Lint   +2 more
doaj   +1 more source

The HIV-1 Subtype C Epidemic in South America Is Linked to the United Kingdom [PDF]

, 2010
Background: The global spread of HIV-1 has been accompanied by the emergence of genetically distinct viral strains. Over the past two decades subtype C viruses, which predominate in Southern and Eastern Africa, have spread rapidly throughout parts of ...
Gifford, RJ, Gifford Robert J., Pillay Deenan, Pillay, D, Tulio de Oliveira, UK Collaborative Grp HIV Drug Resi, Robert J Gifford, Deenan Pillay, de Oliveira, T, UK Collaborative Group on HIV Drug Resistance, de Oliveira Tulio   +10 more
core   +1 more source

Hiding in plain sight – platelets, the silent carriers of HIV-1

Platelets, 2021
There are approximately 38 million people globally living with Human immunodeficiency virus 1 (HIV-1) and given the tremendous success of combination antiretroviral therapy (cART) this has dramatically reduced mortality and morbidity with prevention ...
Yvonne Baumer, Tina M. Weatherby, Brooks I. Mitchell, Ivo N. SahBandar, Thomas A. Premeaux, D’Antoni Michelle L., Cristhian A. Gutierrez-Huerta, Tiffany M. Powell-Wiley, Timothy R. Brown, William A. Boisvert, Cecilia M. Shikuma, Lishomwa C. Ndhlovu   +11 more
doaj   +1 more source

Molecular monitoring of HIV-1 drug resistance in Ifakara HIV-1 Cohort, Tanzania [PDF]

, 2013
HIV-1 resistance is one of the problems affecting success of antiretroviral therapy programmes worldwide. Many studies on efficacy of ART programmes, specifically on drug resistance, have been conducted in developed countries but not in developing ...
Masimba, Pax Jessey
core   +1 more source

Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]

, 2011
BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton, David A. Ross, Watson-Jones Deborah, Weiss, Helen A, Watson-Jones, Deborah, Helen A Weiss, Richard J. Hayes, Laurent Belec, Tanton, Clare, Le Goff, Jerome, Hayes, Richard J, Deborah Watson-Jones, Le Goff Jerome, Belec Laurent, Baisley, Kathy, Changalucha John, Weiss Helen A., Everett Dean, Ross, David A, Everett, Dean, David A Ross, Kathy Baisley, Changalucha, John, Mary Rusizoka, Jerome Le Goff, Helen A. Weiss, John Changalucha, Tanton Clare, Dean Everett, Richard J Hayes, Baisley Kathy, Ross David A., Rusizoka, Mary, Rusizoka Mary, Hayes Richard J., Belec, Laurent   +35 more
core   +1 more source

Infection with HIV-1 [PDF]

BMJ, 1998
Infection with HIV-1 leading to AIDS has been the greatest biomedical challenge of this century. In December 1997 the World Health Organisation estimated that 11.7 million people had died, more than 30 million were still infected, and 16 000 new infections were occurring each day.
openaire   +2 more sources

Chasing the Infecting HIV-1 [PDF]

Clinical Infectious Diseases, 2011
In the absence of an effective prophylactic vaccine and successful viral eradication strategies, the burden of human immunodeficiency virus type 1 (HIV-1) infection and disease continues to grow worldwide. The events characterizing primary HIV-1 infection and the early stages of the infection have been the focus of extensive research addressing the ...
Kinloch-De Loes, S., Geretti, A. M.
openaire   +4 more sources

Everything counts - a method to determine viral suppression among people living with HIV using longitudinal data for the HIV care continuum - results of two large, German, multi-center real-life cohort studies over 20 years (1999–2018)

BMC Public Health, 2021
Background The aim of this study was to develop a standardized method to reconstruct persons’ individual viral load (VL) courses to determine viral suppression and duration of viremia for the HIV care continuum in Germany using longitudinal cohort data ...
Daniel Schmidt, Christian Kollan, Matthias Stoll, Osamah Hamouda, Viviane Bremer, Tobias Kurth, Barbara Bartmeyer, the HIV-1 Seroconverter cohort, the ClinSurv HIV cohort   +8 more
doaj   +1 more source

Tuberculosis in HIV-negative and HIV-infected patients in a low-incidence country: clinical characteristics and treatment outcomes [PDF]

, 2012
BACKGROUND: In Switzerland and other developed countries, the number of tuberculosis (TB) cases has been decreasing for decades, but HIV-infected patients and migrants remain risk groups.
Thomas Bodmer, Gagneux, Sebastien, Bodmer, Thomas, Swiss HIV Cohort and Molecular Epidemiology of Tuberculosis Study Groups, Schrenzel, J., Bottger, E. C., Schrenzel Jacques, Jean-Paul Janssens (174301), Cavassini Matthias, Matthias Egger, Enos Bernasconi (174329), Jacques Schrenzel, Egger, M., Böttger Erik C., Schrenzel, Jacques, Matthias Egger (24558), Böttger, E.C., Jan Fehr (174310), Fehr Jan, Janssens, J. P., Bodmer Thomas, Bernasconi, E., Gagneux, S., Fenner, Lukas, Egger, Matthias, Enos Bernasconi, Egger Matthias, Hoffmann, Matthias, Erik C. Böttger (174343), Cavassini, M., Matthias Hoffmann, Jacques Schrenzel (22586), Janssens, J.P., Böttger, Erik C, Helbling, Peter, Matthias Cavassini (146654), Gagneux Sebastien, Fenner, L., Matthias Hoffmann (174320), Peter Helbling (174346), Helbling, P., Bernasconi, Enos, Jan Fehr, Erik C Böttger, Thomas Bodmer (174337), Lukas Fenner, Fenner Lukas, Fehr, Jan, for the Swiss HIV Cohort and Molecular Epidemiology of Tuberculo,, Janssens, Jean-Paul, Helbling Peter, Bernasconi Enos, Sebastien Gagneux (149824), Janssens Jean-Paul, Hoffmann, M., Hoffmann Matthias, Sebastien Gagneux, Peter Helbling, Lukas Fenner (149822), Jean-Paul Janssens, Fehr, J., Cavassini, Matthias, Bodmer, T., Matthias Cavassini   +63 more
core   +1 more source

The HIV-1 transmission bottleneck [PDF]

Retrovirology, 2017
It is well established that most new systemic infections of HIV-1 can be traced back to one or a limited number of founder viruses. Usually, these founders are more closely related to minor HIV-1 populations in the blood of the presumed donor than to more abundant lineages.
Samuel Mundia Kariuki, Philippe Selhorst, Kevin K. Ariën, Jeffrey R. Dorfman   +3 more
openaire   +4 more sources