Results 141 to 150 of about 1,856,095 (286)

Felid Herpesvirus Type 1 Infection in Cats: A Natural Host Model for Alphaherpesvirus Pathogenesis

ISRN Veterinary Science, 2012
Feline herpesvirus 1 (FeHV-1) is an alphaherpesvirus that causes feline viral rhinotracheitis, an important viral disease of cats on a worldwide basis. Acute FeHV-1 infection is associated with both upper respiratory and ocular signs. Following the acute
R. Maes
semanticscholar   +1 more source

Incidence of HHV‐6 Reactivation in Drug Reaction With Eosinophilia and Systemic Symptoms and Correlation With RegiSCAR Score: A Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
Allison Holt, Baraa Hijaz, Joseph Ebriani, Bethany Brumbaugh, Mike Westmeijer, Madeline E. DeWane, Michael Stephens, John Trinidad, Kevin Sheng‐Kai Ma, Steven T. Chen   +9 more
wiley   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source

The Infectious Etiology of Alzheimer’s Disease

Current Neuropharmacology, 2017
Background: Inflammation is a part of the first line of defense of the body against invasive pathogens, and plays a crucial role in tissue regeneration and repair.
M. Sochocka, K. Zwolińska, J. Leszek
semanticscholar   +1 more source

Parvovirus B19‐associated myocarditis in children: A systematic review of clinical features, management and outcomes

European Journal of Clinical Investigation, EarlyView.
This systematic review summarizes clinical features, diagnostic strategies and outcomes of paediatric myocarditis associated with Parvovirus B19. Affected children are typically under 3 years old and often present with fulminant symptoms, severe cardiac dysfunction and a high need for ICU‐level support or mechanical circulatory assistance.
Giacomo Veronese, Giada Colombo, Andrea Garascia, Rachele Adorisio, Ezio Bonanomi, Enrico Ammirati   +5 more
wiley   +1 more source

Use of Staged Molecular Analysis to Determine Causes of Unexplained Central Nervous System Infections

Emerging Infectious Diseases, 2013
No agent is implicated in most central nervous system (CNS) infections. To investigate cerebrospinal fluid samples from patients with CNS infections of unknown cause in 1 hospital in Taiwan, we used a staged molecular approach, incorporating techniques ...
Chien-Chin Hsu, Rafal Tokarz, Thomas Briese, Hung-Chin Tsai, Phenix-Lan Quan, W. Ian Lipkin   +5 more
doaj   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source

Pathogenic, Molecular, and Immunological Properties of a Virus Associated with Sea Turtle Fibropapillomatosis. Phase II : Viral Pathogenesis and Development of Diagnostic Assays [PDF]

, 2000
Research conducted under this RWO from July 1, 1997 through June 30, 2000 has provided important new information about the pathogenesis, virology, and immunology of marine turtle fibropapillomatosis. In particular, we have provided strong evidence for
Bjorndal, Karen A., Bolten, Alan, Brown, Daniel R., Coberley, Sadie, Ehrhart, Llewellyn, Herbst, Lawrence H., Klein, Paul A., Lackovich, Joel K., Moretti, Ritchie H.   +8 more
core  

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source