Results 1 to 10 of about 26,429 (137)

Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights

open access: yesViruses, 2022
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics. HHVs can induce lytic and latent infections in their host, and most of these viruses are neurotropic, with the capacity to generate severe and chronic neurological ...
Miroslava Šudomová   +5 more
doaj   +1 more source

Detection of Herpesviruses in Wild Bird Casualties in Slovenia

open access: yesFrontiers in Veterinary Science, 2022
The complete host range of avian herpesviruses in wild birds is unknown, and information about nucleotide sequences is available only in limited cases.
Zoran Žlabravec   +7 more
doaj   +1 more source

Herpesvirus late gene expression: a viral-specific Pre-Initiation Complex is key

open access: yesFrontiers in Microbiology, 2016
During their productive cycle, herpesviruses exhibit a strictly regulated temporal cascade of gene expression that can be divided into three general stages: immediate-early (IE), early (E) and late (L).
Henri eGruffat   +14 more
doaj   +1 more source

Post-mortem detection of six human herpesviruses (HSV-1, HSV-2, VZV, EBV, CMV, HHV-6) in trigeminal and facial nerve ganglia by PCR [PDF]

open access: yesPeerJ, 2019
Background Among over 100 types of Herpesviridae viruses, eight can infect humans: herpes simplex viruses (HSV-1, HSV-2), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), and human herpesviruses 6, 7, and 8 (HHV-6, HHV-7 ...
Iwona Ptaszyńska-Sarosiek   +6 more
doaj   +2 more sources

Experimental Justification of Reprofiling of the Drug Maxar® for the Treatment of Viral Infections

open access: yesАнтибиотики и Химиотерапия, 2023
Relevance. The development of highly effective broad-spectrum antiviral agents is one of the priorities in medicine, virology, and pharmacology. The strategy of repurposing (repositioning) registered drugs is of special interest along with significant ...
T. S. Zaporozhets   +7 more
doaj   +1 more source

Prolonged Herpetic Keratitis in Chronic Sinusitis and Tonsillitis: Experience of Practical Solutions

open access: yesOftalʹmologiâ, 2023
Aim: to describe the experience of practical solutions for herpetic keratitis of a protracted course with latent chronic sinusitis and tonsillitis.Material and methods.
G. M. Chernakova   +3 more
doaj   +1 more source

Identification of Amino Acids Essential for Viral Replication in the HCMV Helicase-Primase Complex

open access: yesFrontiers in Microbiology, 2018
Promising new inhibitors that target the viral helicase-primase complex have been reported to block replication of herpes simplex and varicella-zoster viruses, but they have no activity against human cytomegalovirus (HCMV), another herpesvirus.
Gaetan Ligat   +6 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Serological evidence of herpesvirus infection in gibbons

open access: yesBMC Microbiology, 2002
Background Herpesviruses are not only infectious agents of worldwide distribution in humans, but have also been demonstrated in various non-human primates as well.
Ratanakorn Parntep   +4 more
doaj   +1 more source

‘Come together’—The Regulatory Interaction of Herpesviral Nuclear Egress Proteins Comprises Both Essential and Accessory Functions

open access: yesCells, 2022
Herpesviral nuclear egress is a fine-tuned regulatory process that defines the nucleocytoplasmic release of viral capsids. Nuclear capsids are unable to traverse via nuclear pores due to the fact of their large size; therefore, herpesviruses evolved to ...
Sigrun Häge, Manfred Marschall
doaj   +1 more source

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