Results 11 to 20 of about 26,429 (137)

Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics

open access: yesFrontiers in Microbiology, 2015
Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts.
Charlotte J Houldcroft   +2 more
exaly   +3 more sources

Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases?

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of their lives. The relationship of immunocompetent healthy host with herpesviruses may sometime be considered as harmonious.
Sharvan Sehrawat   +2 more
exaly   +3 more sources

Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposi’s Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell-Specific Manner

open access: yesmBio, 2021
The interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral proteins that inhibit the entry of enveloped viruses. We analyzed the effect of IFITMs on the gamma-2 herpesviruses Kaposi’s sarcoma-associated herpesvirus (KSHV) and the
Bojan F. Hörnich   +4 more
doaj   +1 more source

Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins

open access: yesViruses, 2023
Foamy viruses (FVs) are naturally found in many different animals and also in primates with the notable exception of humans, but zoonotic infections are common. In several species, two different envelope (env) gene sequence clades or genotypes exist.
Thomas Fricke   +7 more
doaj   +1 more source

Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms

open access: yesViruses, 2022
Kaposi’s sarcoma herpesvirus (KSHV) is associated with a significant disease burden, in particular in Sub-Sahara Africa. A KSHV vaccine would be highly desirable, but the mechanisms underlying neutralizing antibody responses against KSHV remain largely ...
Thomas Fricke   +4 more
doaj   +1 more source

Significance of herpesvirus infections in the etiology of bronchopulmonary complications in patients undergoing heart transplantation [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2023
Objective. To study significance of herpesviruses in the development of infectious complications in patients after heart transplantation based on the detection of markers of herpesvirus infections. Materials and Methods.
Karazhas N.V.   +9 more
doaj   +1 more source

Genetic and Functional Characterization of Congenital HCMV Clinical Strains in Ex Vivo First Trimester Placental Model

open access: yesPathogens, 2023
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, leading to a variety of symptoms in the unborn child that range from asymptomatic to death in utero.
Deborah Andouard   +8 more
doaj   +1 more source

Anti-CMV therapy, what next? A systematic review

open access: yesFrontiers in Microbiology, 2023
Human cytomegalovirus (HCMV) is one of the main causes of serious complications in immunocompromised patients and after congenital infection. There are currently drugs available to treat HCMV infection, targeting viral polymerase, whose use is ...
Claire Gourin   +4 more
doaj   +1 more source

Investigation on colorectal cancer and human herpesvirus infection among Algerian patients

open access: yesJournal of Infection in Developing Countries, 2023
Introduction: Herpesviruses are a widespread family of double-stranded DNA viruses that establish life-long persistent infection in their hosts. Cumulative evidence tends to argue for the association of human herpesviruses, such as Kaposi's sarcoma ...
Amina Bouchemal   +7 more
doaj   +1 more source

The impact of viral infections on the results of hemopoietic stem cell transplantation in patients with hematologic malignancies

open access: yesЖурнал инфектологии, 2021
Study Objective: to assess the impact of herpesviruses infections reactivation and concomitant chronic hepatitis C infection (CHC) on complications and one-year survival after hemopoietic stem cell transplantation (HSCT) in patients with hematologic ...
T. V. Antonova   +4 more
doaj   +1 more source

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