Results 61 to 70 of about 36,154,205 (252)

Reciprocal Regulatory Interaction between Human Herpesvirus 8 and Human Immunodeficiency Virus Type 1 [PDF]

Journal of Biological Chemistry, 2001
Human herpesvirus 8 (HHV8) is the primary viral etiologic agent in Kaposi's sarcoma (KS). However, individuals dually infected with both HHV8 and human immunodeficiency virus type 1 (HIV-1) show an enhanced prevalence of KS when compared with those singularly infected with HHV8.
Huang, LM, Chao, MF, Chen, MY, Shih, HM, Chiang, YP, Chuang, CY, Lee, CY   +6 more
openaire   +2 more sources

Identification and localization of the structural proteins of anguillid herpesvirus 1 [PDF]

, 2011
peer ...
Leroy, B, Vervoort Jacques JM, Dep Infectieziekten Immunologie, Vanderplasschen, A.F., Ruddy Wattiez, Alain F Vanderplasschen, Boeren, S., Vervoort, J, Engelsma, M, van Beurden, S.J., Van Beurden, Steven, Haenen, O, Leroy Baptiste, Leroy, B., Wattiez, R, van Beurden Steven J, Engelsma Marc Y, Boeren, S, Vanderplasschen Alain F, Beurden, S.J., van, Olga LM Haenen, Peeters, B, Rottier, P, Boeren Sjef, Vervoort, J.M., Vanderplasschen, Alain, Baptiste Leroy, Marc Y Engelsma, Haenen Olga LM, Leroy, B.P., Rottier Peter JM, Rottier, P.J.M., Wattiez, R., Peeters Ben PH, Peter JM Rottier, Peeters, B.P.H., Sjef Boeren, Strategic Infection Biology, Haenen, O.L.M., Engelsma, M.Y., Vanderplasschen, A., Jacques JM Vervoort, Steven J van Beurden, Ben PH Peeters, Wattiez Ruddy, Vervoort, J.J.M.   +45 more
core   +2 more sources

CASTOR1 regulates humoral immune responses and contributes to the pathogenesis of systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objectives CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda, Toshihiko Komai, Takahiro Itamiya, Tatsuki Abe, Tomohisa Okamura, Keishi Fujio   +5 more
wiley   +1 more source

Tumorigenesis by Human Herpesvirus 8 vGPCR Is Accelerated by Human Immuodeficiency Virus Type 1 Tat [PDF]

Journal of Virology, 2004
ABSTRACTHuman herpesvirus 8 (HHV-8), also called Kaposi's sarcoma (KS) herpesvirus, can cause KS but is inefficient. Untreated human immunodeficiency virus type 1 (HIV-1) coinfection is a powerful risk factor. The HHV-8 chemokine receptor, vGPCR (ORF74), activates NF-κB and NF-AT, and their levels of activation are synergistically increased by HIV-1 ...
Hong-Guang, Guo, Shibani, Pati, Mariola, Sadowska, Man, Charurat, Marvin, Reitz   +4 more
openaire   +2 more sources

Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1 [PDF]

, 2008
The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs.
Stewart, James P., Russell, George C, Inglis, Neil F, Imrie, Lisa, Dry, Inga, Haig, David M   +5 more
core  

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

EBV induced loss of sperm quality

Urology Research and Practice, 2021
Objective: To analyze the presence of Epstein–Barr-virus (EBV) in sperm samples from patients diagnosed with some impairment of the fertility parameters evaluated using seminogram and to observe if there is any difference with the normozoospermic samples.
Manuel Huerta, Jennifer Thönnisen, Barbara Köditz, Jan Herden, Johan Denil, Pia Paffenholz, Axel Heidenreich, Melanie von Brandenstein   +7 more
doaj   +1 more source

Human herpesvirus 6 inhibits human immunodeficiency virus type 1 replication in cell culture [PDF]

Journal of Clinical Microbiology, 1990
The SF strain of human herpesvirus 6 (HHV-6SF) isolated from the saliva of a human immunodeficiency virus (HIV)-infected individual was shown to inhibit HIV type 1 (HIV-1) replication in both peripheral blood mononuclear cells and purified CD4+ lymphocytes. This suppression of HIV-1 replication led to decreased cytopathic effects of HIV-1 and prolonged
J A, Levy, A, Landay, E T, Lennette
openaire   +2 more sources

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]

, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J, Baquero, B, Jennifer J Wood, Adrian Whitehouse, Belinda Baquero-Pérez (706834), Hughes, DJ, David J Hughes, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Hughes, David John, Jackson, Brian R, Belinda Baquero-Pérez, Adrian Whitehouse (179093), Brian R Jackson, Brian R. Jackson (233567), Wood, JJ, Jennifer J. Wood (706833), David J. Hughes (167294), Baquero-Pérez, Belinda   +19 more
core   +1 more source

Purification and concentration of model viruses using single‐pass tangential flow filtration

Biotechnology Progress, EarlyView.
Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano, Lynn Manchester, Grace Wallis, Kan Wang, Bruce P. Lee, Michael Betenbaugh, Caryn L. Heldt   +6 more
wiley   +1 more source