Results 31 to 40 of about 1,555 (150)

Genetic evolution of Gallid herpesvirus 2 isolated in China

open access: yesInfection, Genetics and Evolution, 2017
Gallid herpesvirus 2 (GaHV-2), which causes Marek's disease in chickens and has caused extensive economic losses, has recently evolved increased virulence in China. To better understand the genetic basis of the pathogenic characteristics changed and increased virulence, we sequenced the genomes of six new GaHV-2 strains (LCC, LTS, WC/1203, JL/1404, CC ...
Hongchao Lv   +12 more
openaire   +2 more sources

Marek’s Disease Virus (Gallid alphaherpesvirus 2)-Encoded miR-M2-5p Simultaneously Promotes Cell Proliferation and Suppresses Apoptosis Through RBM24 and MYOD1-Mediated Signaling Pathways

open access: yesFrontiers in Microbiology, 2020
MicroRNAs (miRNAs) have been demonstrated for their involvement in virus biology and pathogenesis, including functioning as key determinants of virally-induced cancers.
Zhi-Jian Zhu   +20 more
doaj   +1 more source

PFOS mediates immunomodulation in an avian cell line that can be mitigated via a virus infection

open access: yesBMC Veterinary Research, 2019
Background Per- and polyfluoroalkyl substances (PFASs) are environmentally persistent and bioaccumulative chemicals. Immunomodulation is among the most concerning of toxic effects linked with PFAS exposure in mammalian models. However, no studies had yet
Jose M. Castaño-Ortiz   +2 more
doaj   +1 more source

Marek’s Disease Virus Cluster 3 miRNAs Restrict Virus’ Early Cytolytic Replication and Pathogenesis

open access: yesViruses, 2020
Herpesvirus-encoded microRNAs (miRNAs) have been discovered in infected cells; however, lack of a suitable animal model has hampered functional analyses of viral miRNAs in vivo.
Yifei Liao   +5 more
doaj   +1 more source

Case Report: Esophagitis and pharyngitis associated with avian infectious laryngotracheitis in backyard chickens: 2 cases [PDF]

open access: yes, 2017
Infectious laryngotracheitis (ILT) is a contagious viral respiratory disease of great economic importance for the global poultry industry caused by Gallid herpesvirus 1 (GaHV-1).
Boulianne, Martine   +5 more
core   +1 more source

Common occurrence ofGallid herpesvirus-2with reticuloendotheliosis virus in chickens caused by possible contamination of vaccine stocks [PDF]

open access: yesJournal of Applied Microbiology, 2015
The aim of this study was to investigate the common occurrence of reticuloendotheliosis virus (REV) among Gallid herpesvirus 2 (GaHV-2) infected chickens. The possible cause of this co-occurrence may be linked to contaminated vaccine stocks, which were also examined.The study was conducted on 25 field isolates of GaHV-2 collected between 2007 and 2013 ...
G, Woźniakowski   +2 more
openaire   +2 more sources

Herpes virus infection associated with interstitial nephritis in a beaked whale (Mesoplodon densirostris) [PDF]

open access: yes, 2012
Background The capacity for herpesvirus to cause disease in cetaceans is unclear and may be varied depending on the different conditions of individuals and between different species. Kidney pathology and intralesional virus-associated infection have been
Antonio Fernández   +8 more
core   +2 more sources

A Tiny RNA that Packs a Big Punch: The Critical Role of a Viral miR-155 Ortholog in Lymphomagenesis in Marek’s Disease

open access: yesFrontiers in Microbiology, 2017
MicroRNAs (miRNAs) are small non-coding RNAs that have been identified in animals, plants, and viruses. These small RNAs play important roles in post-transcriptional regulation of various cellular processes, including development, differentiation, and ...
Guoqing Zhuang   +4 more
doaj   +1 more source

In vivo expression patterns of microRNAs of Gallid herpesvirus 2 (GaHV-2) during the virus life cycle and development of Marek’s disease lymphomas [PDF]

open access: yesVirus Genes, 2015
In the past decade, a large number of microRNAs (miRNAs) have been identified in the viral genome of Gallid herpesvirus 2 (GaHV-2), which is historically known as Marek's disease virus type 1. The biological role of most GaHV-2 miRNAs remains unclear. In the present study, we have performed an overall gene expression profile of GaHV-2 miRNAs during the
Zhao, Pu   +8 more
openaire   +2 more sources

An Overview on Marek’s Disease Virus Evolution and Evidence for Increased Virulence in Brazil

open access: yesBrazilian Journal of Poultry Science, 2019
Marek’s disease virus (MDV) has been shown to be evolving to higher virulence. One of the genetic sites involved in virulence which enables such characterization is the 339-amino acid Meq protein encoding gene (meq).
ACD Torres   +3 more
doaj   +1 more source

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