Results 1 to 10 of about 2,840 (146)

Surveillance and Molecular Characterization of Marek’s Disease Virus (MDV) Strains Circulating in Tanzania [PDF]

Viruses
Marek’s disease (MD) is a highly contagious and oncogenic viral disease of poultry, causing significant economic losses due to mortality and reduced performance. The rapid evolution of Marek’s disease virus (MDV) has been reported in poultry farms, often
Augustino Alfred Chengula, Herbertha Mpete, Ramadhani Juma Makasali   +2 more
doaj   +2 more sources

Two distinct polymorphisms in the basic region of Meq protein of marek’s disease virus alter pathological progression and clinical manifestations [PDF]

Virology Journal
Background Marek’s disease virus (MDV) causes Marek’s disease (MD) in chickens, which is characterized by malignant lymphomas and neurological disorders.
Jumpei Sato, Aoi Kurokawa, Yoshinosuke Motai, Shunsuke Yamagami, Shwe Yee Win, Fumiya Horio, Hikaru Saeki, Naoya Maekawa, Tomohiro Okagawa, Benedikt B. Kaufer, Nikolaus Osterrieder, Mark S. Parcells, Satoru Konnai, Kazuhiko Ohashi, Shiro Murata   +14 more
doaj   +2 more sources

Updating of epidemiological and pathological features of Marek's disease in laying hens and broilers [PDF]

Veterinární Medicína, 2023
Marek's disease (MD) is a huge problem for researchers due to the significant losses in bird flocks, but more importantly, the virus's mutagenic potential.
M Zeghdoudi, M Latifa, M Seloua, S Rima, T Mardja, L Aoun   +5 more
doaj   +2 more sources

The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus [PDF]

Scientific Reports, 2023
Genetically resistant or susceptible chickens to Marek’s disease (MD) have been widely used models to identify the molecular determinants of these phenotypes.
Wesley C. Warren, Edward S. Rice, Ashley Meyer, Cari J. Hearn, Alec Steep, Henry D. Hunt, Melissa S. Monson, Susan J. Lamont, Hans H. Cheng   +8 more
doaj   +2 more sources

Comparative transcriptomic analysis of chicken immune organs affected by Marek’s disease virus infection at latency phases [PDF]

Frontiers in Physiology
Over the past decades, MDV has dramatically evolved towards more virulent strains and remains a persistent threat to the world’s poultry industry.
Yi Ding, John Dunn, Huanmin Zhang, Keji Zhao, Jiuzhou Song   +4 more
doaj   +2 more sources

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Viruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato, Shiro Murata, Zhiyuan Yang, Benedikt B. Kaufer, Sotaro Fujisawa, Hikari Seo, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Nikolaus Osterrieder, Mark S. Parcells, Kazuhiko Ohashi   +11 more
doaj   +1 more source

Outbreak of Marek’s Disease in Chicken Flocks with Uncommon Pattern of Gross Lesions [PDF]

Journal of Veterinary and Animal Sciences, 2023
Marek’s disease is one of the highly contagious and oncogenic diseases of poultry that remains as a threat to the fast-growing poultry sector, even after proper vaccination.
R. Geethanjali , M. Pradeep, P. Hamza, R. Rajasekhar, A.J. George   +4 more
doaj   +1 more source

A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021

Animals, 2022
Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key
Baolin Song, Jehan Zeb, Sabir Hussain, Muhammad Umair Aziz, Elena Circella, Gaia Casalino, Antonio Camarda, Guan Yang, Nicolas Buchon, Olivier Sparagano   +9 more
doaj   +1 more source

B cells do not play a role in vaccine-mediated immunity against Marek’s disease

Vaccine: X, 2022
Background: Marek’s disease virus (MDV), a highly oncogenic α-herpesvirus, is the etiological agent of Marek’s disease (MD) in chickens. The antiviral activity of vaccine-induced immunity against MD reduces the level of early cytolytic infection ...
Mohammad Heidari, Huanmin Zhang, Cari Hearn, Lakshmi Sunkara   +3 more
doaj   +1 more source

The Regulatory Microenvironment in Feathers of Chickens Infected with Very Virulent Marek’s Disease Virus

Viruses, 2022
Vaccines against Marek’s disease can protect chickens against clinical disease; however, infected chickens continue to propagate the Marek’s disease virus (MDV) in feather follicles and can shed the virus into the environment.
Jegarubee Bavananthasivam, Nadiyah Alqazlan, Mohammadali Alizadeh, Ayumi Matsuyama-Kato, Jake Astill, Raveendra R. Kulkarni, Shayan Sharif   +6 more
doaj   +1 more source