Microsatellite Markers Associated with Resistance to Marek’s Disease in Commercial Layer Chickens [PDF]
The objective of the current study was to identify QTL conferring resistance to Marek\u27s disease (MD) in commercial layer chickens. To generate the resource population, 2 partially inbred lines that differed in MD-caused mortality were intermated to ...
Cheng, H. H. +10 more
core +3 more sources
Transcriptome Analysis in Spleen Reveals Differential Regulation of Response to Newcastle Disease Virus in Two Chicken Lines. [PDF]
Enhancing genetic resistance of chickens to Newcastle Disease Virus (NDV) provides a promising way to improve poultry health, and to alleviate poverty and food insecurity in developing countries.
Bunn, David A +8 more
core +3 more sources
Isolation and analysis of a very virulent Marek’s disease virus strain in China [PDF]
BACKGROUND: A severe MD was broken out at a farm in Shandong, China, despite FC126 vaccination of the chickens at 1-day-old. The mortality of the flocks reached up to 38.3%.
Hongchao Ma +6 more
core +1 more source
A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America [PDF]
Virulence determines the impact a pathogen has on the fitness of its host, yet current understanding of the evolutionary origins and causes of virulence of many pathogens is surprisingly incomplete. Here, we explore the evolution of Marek's disease virus
Groenke, Nicole +8 more
core +1 more source
A full UL13 open reading frame in Marek’s disease virus (MDV) is dispensable for tumor formation and feather follicle tropism and cannot restore horizontal virus transmission of rRB-1B in vivo [PDF]
peer reviewedMarek’s disease virus (MDV) is an oncogenic alphaherpesvirus that is highly contagious in poultry. Recombinant RB-1B (rRB-1B) reconstituted from an infectious genome cloned as a bacterial artificial chromosome (BAC) is unable to spread ...
Beaumont, Catherine +6 more
core +4 more sources
Figure S1. Histogram plot of MD incidence (%) rate. MD resistance in chickens is generally evaluated with MD incidence (induced gross tumors by MDV) and survival day post MDV challenge, and the extent of resistance is dependent of the virulence of challenge viruses and other factors. Figure S2.
Xu, Lingyang +7 more
openaire +1 more source
Integrated Genomic Approaches to Enhance Genetic Resistance in Chickens [PDF]
The chicken has led the way among agricultural animal species in infectious disease control and, in particular, selection for genetic resistance. The generation of the chicken genome sequence and the availability of other empowering tools and resources ...
Cheng, Hans +3 more
core +3 more sources
Table S1. Primer sets of five candidate lncRNAs and IGF-I used in quantitative PCR analysis; QPCR gel picture of five candidate lncRNAs; (DOCX 729 kb)
You, Zhen +5 more
openaire +1 more source
Genotype-Dependent Tumor Regression in Marek’s Disease Mediated at the Level of Tumor Immunity [PDF]
Research Article published by SpringerMarek’s disease (MD) of chickens is a unique natural model of Hodgkin’s and Non Hodgkin’s lymphomas in which the neoplastically-transformed cells over-express CD30 (CD30hi) antigen.
Shyamesh Kumar +45 more
core +1 more source
Figure S2. Heatmaps of DE lncRNAs between the tumorous spleens and noninfected spleens. a the expression level of DE putative lncRNAs in each individual from the tumorous spleens and noninfected spleens. b DE known lncRNAs in each individual from the tumorous spleens and noninfected spleens. (PDF 57 kb)
You, Zhen +5 more
openaire +1 more source

