Results 81 to 90 of about 942 (103)

Role of the multiple telomeric repeat arrays in integration, persistence, and efficacy of the commercial CVI988 vaccine. [PDF]

open access: yesmSphere
Bertzbach LD   +7 more
europepmc   +1 more source

Extracellular vesicles released from Marek's disease virus-transformed T-cells impact immune cell proliferation. [PDF]

open access: yesJ Gen Virol
Trapp-Fragnet L   +5 more
europepmc   +1 more source
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Marek's disease: Genetic regulation of gallid herpesvirus 2 infection and latency

The Veterinary Journal, 2015
Gallid herpesvirus-2 (GaHV-2) is an oncogenic α-herpesvirus that causes Marek's disease (MD), a T cell lymphosarcoma (lymphoma) of domestic fowl (chickens). The GaHV-2 genome integrates by homologous recombination into the host genome and, by modulating expression of viral and cellular genes, induces transformation of latently infected cells.
Gennart, Isabelle   +5 more
openaire   +5 more sources

Sequence determination of variable regions within the genomes of gallid herpesvirus-2 pathotypes

Archives of Virology, 2007
Comparative genomic studies of attenuated and virulent strains of Gallid herpesvirus 2 (GaHV-2) have identified 6 regions of sequence variability. These regions include the open reading frames (ORFs) encoding UL36 and UL49 and regions devoid of large ORFs (132-bp repeats, a-like sequences and the junctions flanking the unique short region).
S J, Spatz, R F, Silva
openaire   +2 more sources

Comparative study on biological material for molecular diagnosis of Gallid herpesvirus 2

Indian Journal of Animal Research, 2018
The present study was intended to investigate the sensitivity of different tissues of tumorous and non-tumorous birds to the polymerize chain reaction-baseddiagnosis of Marek’s disease. Tissue samples were collected from spleen, sciatic nerve, feather follicles and tumour parts (if any)of chickens during the routine necropsy examination.
Venkataramireddy Balena   +2 more
openaire   +1 more source

Gallid herpesvirus 1 (infectious laryngotracheitis virus): cloning and physical maps of the SA-2 strain

Archives of Virology, 1991
Clones representing 90% of the genome of Gallid herpesvirus 1 (infectious laryngotracheitis virus; ILTV) were obtained and used in hybridization experiments to construct EcoRI, KpnI amd SmaI physical maps. The genome was 155 kilobase pairs (kbp) and comprised of a long unique sequence (120 kbp) and a short unique sequence (17 kbp) bounded by repeat ...
M A, Johnson   +4 more
openaire   +2 more sources

Characterization of a Gallid herpesvirus 2 strain with novel reticuloendotheliosis virus long terminal repeat inserts

Virus Genes, 2017
A bacterial artificial chromosome clone, designated LCY, was constructed from a Gallid herpesvirus 2 (GaHV-2) isolate from a GaHV-2 and reticuloendotheliosis virus co-infected clinical sample. The LCY GaHV-2 insert was sequenced and found to consist of 175,319 nucleotides.
Yan-Ping, Zhang   +7 more
openaire   +2 more sources

Sequence determination of a mildly virulent strain (CU-2) of Gallid herpesvirus type 2 using 454 pyrosequencing

Virus Genes, 2008
The complete DNA sequence of the mildly virulent Gallid herpesvirus type 2 strain CU-2 was determined and consists of 176,922 bp with an overall gene organization typical of class E herpesviruses. Phylogenetically, this strain partitions in its own branch between the virulent strains RB-1B, Md11, and Md5, and the vaccine strain CVI988.
Stephen J, Spatz, Cary A, Rue
openaire   +2 more sources

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