Molecular characterization of Marek's Disease virus reveals reticuloendotheliosis virus-long terminal repeat integration in the genome of the field isolates in Egypt. [PDF]
Emad A, El-Kenawy AA, El-Tholoth M.
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Epidemiology of Marek's Disease Virus Type 2 and the Molecular and Pathology Characterization of Virus Isolates in China (2015-2024). [PDF]
Lin Y +13 more
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Comprehensive Analysis of Liver Transcriptome and Metabolome Response to Oncogenic Marek's Disease Virus Infection in Wenchang Chickens. [PDF]
Zhi L +7 more
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Fatal tracheal collapse and ossification in an osteopenic captive Indian blue peafowl in California. [PDF]
Gornatti-Churria CD +4 more
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A meta-analysis for prevalence of infectious laryngotracheitis in chickens in mainland China in 1981-2022. [PDF]
Hong X +4 more
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Marek's disease: Genetic regulation of gallid herpesvirus 2 infection and latency
Veterinary Journal, 2015Gallid herpesvirus-2 (GaHV-2) is an oncogenic α-herpesvirus that causes Marek's disease (MD), a T cell lymphosarcoma (lymphoma) of domestic fowl (chickens). The GaHV-2 genome integrates by homologous recombination into the host genome and, by modulating expression of viral and cellular genes, induces transformation of latently infected cells.
Damien Coupeau +2 more
exaly +6 more sources
Previous studies demonstrated that telomerase RNAs possess functions that promote tumor development independent of the telomerase complex. vTR is a herpesvirus-encoded telomerase RNA subunit that plays a crucial role in virus-induced tumorigenesis and is expressed by a robust viral promoter that is highly regulated by the c-Myc oncoprotein binding to ...
Benoit Muylkens +2 more
exaly +3 more sources
Sequence determination of variable regions within the genomes of gallid herpesvirus-2 pathotypes
Archives of Virology, 2007Comparative genomic studies of attenuated and virulent strains of Gallid herpesvirus 2 (GaHV-2) have identified 6 regions of sequence variability. These regions include the open reading frames (ORFs) encoding UL36 and UL49 and regions devoid of large ORFs (132-bp repeats, a-like sequences and the junctions flanking the unique short region).
R F Silva
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Phylogeny and recombination history of gallid herpesvirus 2 (Marek's disease virus) genomes [PDF]
Phylogenetic analyses based on concatenated amino acid sequences from orthologous loci from eight genomes of alpha herpesviruses infecting birds provided strong support for the following hypotheses: (1) gallid HV3 is a sister taxon to gallid HV2 but gallid HV1 is not closely related to the other two chicken herpesviruses; (2) meleagrid HV1 is closer to
Austin L, Hughes, Pierre, Rivailler
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A bacterial artificial chromosome clone, designated LCY, was constructed from a Gallid herpesvirus 2 (GaHV-2) isolate from a GaHV-2 and reticuloendotheliosis virus co-infected clinical sample. The LCY GaHV-2 insert was sequenced and found to consist of 175,319 nucleotides.
Hong-Yu Cui +2 more
exaly +3 more sources

